Antibodies in Mom Linked to Autism in Kids Jul 10, 2013 By Salynn Boyles, Contributing Writer, MedPage Today [Reviewed by Zalman S. Agus, MD; Emeritus Professor, Perelman School of Medicine at the University of Pennsylvania and Dorothy Caputo, MA, BSN, RN, Nurse Planner].
Maternal autoantibodies that target key proteins in the fetal brain could explain almost one in four cases of autism, according to two studies published online this week in the journal Translational Psychiatry.
In one study, researchers from the University of California, Davis MIND Institute identified seven antigens specific to autism and then showed that the antibodies to these antigens were present in the blood of 23% of mothers who had children with the disorder and less than 1% of mothers with normally developing children.
In a second study, female rhesus monkeys exposed while pregnant to the autism-specific antibodies from the blood of mothers of children with autism gave birth to offspring that displayed behavioral traits consistent with the disorder. Male monkeys, but not females, born to the antibody-exposed mothers also had brain growth patterns consistent with male children with autism, seen in neuroimaging studies.
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Antibodies in Mom Linked to Autism in Kids Jul 10, 2013 By Salynn Boyles, Contributing Writer, MedPage Today
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