New US Report MMR Vaccine Causes Serious Conditions – Says US Institute of Medicine – Measles, Seizures, Anaphylaxis & Many More

NaturalNews has published an article reviewing the recent US Institute of Medicine [IOM] Report on MMR vaccines.  You can download and view the report yourself: Adverse Effects of Vaccines Evidence Causality

The full NaturalNews article can be read here:

Institute of Medicine adverse reactions report admits MMR vaccines cause measles, seizures, anaphylaxis and other health problems Sunday, August 28, 2011 by Mike Adams, the Health Ranger Editor of NaturalNews.com

The IOM conclusion that “vaccines do not cause autism” is erroneous.  Someone should tell them US Government agencies, officials and medical experts do not agree:

Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines

And the IOM did not interview any parent of an autistic child nor conduct a medical review of any autistic children.

___________

“The Institute of Medicine ……. has issued a report that declares the MMR vaccine is not linked to autism.  This is now being widely reported in the conventional (controlled) media, which isn’t telling you the real story.

That this IOM report now confirms that vaccines cause measles, febrile seizures, anaphylactic shock and other potentially fatal side effects. It also admits that other vaccines are linked to a wide range of side effects, including skin lesions, difficulty breathing and live virus infections (see complete list, below).

Conclusions of the Institute of Medicine report on vaccine adverse reactions

Here are some of the conclusions of the IOM’s report not reported in the media:

MMR vaccine is “convincingly” linked to causing measles. (Just as we told you here on NaturalNews, the vaccine is what’s causing the disease.)

MMR vaccine is “convincingly” linked to causing febrile seizure, just as we also reported here on NaturalNews.

MMR vaccine is “convincingly” linked to causing anaphylaxis, a life-threatening allergic reaction that can result in death within minutes. This is what kills many young children who are injected with MMR vaccines.

MMR vaccine is likely linked to causing transient arthralgia in women and children.

Varicella vaccine is “convincingly” linked to causing Disseminated Oka VZV, a viral disease (Varicella Zoster Virus) which causes skin lesions and can also infect the lungs and brain. The fact that this vaccine is causing VZV infections is proof that the vaccines contain live viruses!

Varicella vaccine is “convincingly” linked to causing Vaccine Strain Viral Reactivation, meaning the vaccine contains live viruses that are reactivated in the human host, multiplying and causing widespread infections.

Varicella vaccine is “convincingly” linked to causing anaphylaxis, the life-threatening allergic reaction mentioned above.

The influenza vaccine is “convincingly” linked to causing anaphylaxis

The influenza vaccine likely causes Oculorespiratory Syndrome, a vaccine reaction described as causing “bilateral conjunctivitis, facial edema, and upper respiratory symptoms.

The Hepatitis B vaccine is “convincingly” linked to causing anaphylaxis.

The HPV vaccine (for cervical cancer) is also likely linked to causing anaphylaxis.

The TT (Tetanus Toxoid) vaccine is also likely linked to causing anaphylaxis.

The Meningo-Coccal vaccine is “convincingly” linked to causing anaphylaxis.

Vaccine injections (of all kinds) are “convincingly” linked to causing Deltoid Bursitis (severe pain and swelling at the injection site) and Syncope (loss of consciousness). 

What the IOM report on vaccines also reveals

 The IoM study admits vaccines cause infectious disease!

The IoM report confirms that MMR vaccines cause measles. It describes the evidence as “convincingly supports” and says the mechanistic assessment is “strong.”

The IoM report dismissed any link between vaccines and a list of conditions based on a “lack of sufficient evidence“. 

[ED: But if you read these CHS articles you can judge for yourself the value of this list:

US Government Concedes Hep B Vaccine Causes Systemic Lupus Erythematosus Posted on April 25, 2011,

UK Government Caught Lying On Baby Hep B Vax Safety Posted on April 13, 2009 by childhealthsafety

Hepatitis B vaccine has been shown in many peer reviewed research papers [including from Harvard University – detailed references at end] to be associated with numerous infant deaths in the USA and Europe, multiple sclerosis and numerous chronic auto-immune disorders.  These latter include Guillain-Barre syndrome, lupus, rheumatism, blood disorders and chronic fatigue.  ].

This is what the IOM say are not caused by vaccines:-

Guillain-Barre Syndrome
Multiple Sclerosis
Chronic Inflammatory Disseminated Polyneuropathy
Asthma Exacerbation
Autism
Lupus
Type-1 diabetes
Rheumatoid arthritis
Autoimmune hepatitis
Chronic Fatigue Syndrome
Fibromyalgia
Meningitis
Myocardial Infarction
Infantile spasms
Optic neuritis
Bell’s Palsy
Arthropathy
Encephalopathy
Transverse myelitis
Sudden Infant Death Syndrome

The IOM admits it did not consider the “benefits” of vaccines

We were not charged with assessing the benefits of vaccines, with weighing benefits and costs, or with deciding how, when, and to whom vaccines should be administered. The committee was not charged with making vaccine policy,” says Ellen Wright Clayton of the Chair Committee to Review Adverse Effects of Vaccines.

The report says:

The 2009 H1N1 influenza vaccine is covered by the Countermeasures Injury Compensation Program, and evidence about its safety is not covered in this report.”

The IoM admits it did not have accurate data

In the introduction to the report, the IoM admits it doesn’t have enough data to accurately assess the totality of vaccine adverse reactions.

…we learned some lessons that may be of value for future efforts to evaluate vaccine safety. One is that some issues simply cannot be resolved with currently available epidemiologic data…”

The IoM effectively admits that many vaccine side effects are blamed on the “natural infection.”

Some adverse events caused by vaccines are also caused by the natural infection. These effects often cannot be detected by epidemiologic methods, which typically cannot distinguish between the adverse events that are caused by the vaccine itself and the decrease in adverse events due to the decreased rate of natural infection.”

The IoM admits it threw out all data covering long-term adverse events

All the conclusions of the IoM are based on short-term adverse reactions from single vaccines. The IoM’s report did not consider long-term adverse reactions or the cumulative effects of multiple vaccines compromising the immune system or nervous system.

The IoM admits:

Case descriptions that did not have the three basic elements described above were not considered in the mechanistic weight-of-evidence assessments.”

One of those three elements was a “specified and reasonable time interval (i.e., temporality or latency) between vaccination and symptoms.” But the IoM failed to define this “temporality” stating that “What constitutes reasonable latency will vary across vaccines and across adverse events.

The Institute of Medicine

The IoM declared Agent Orange was safe for U.S. veterans who fought in Vietnam.

The IoM  was directly involved in the unlawful medical experiments conducted on Guatemalan prisoners, a “dark chapter” of conventional medical history that came to light in late 2010.

When these experiments became known President Obama was forced to issue a public apology and organize an investigation.  He appointed the Institute of Medicine to lead the investigation.

But the IoM had to recuse itself, admitting that some of its own people conducted the illegal medical experiments. The Guatemalan medical experiments were a U.S. government funded operation conducted under the NIH.  The IoM has strong financial ties to the government, receiving as much as 64.9% of its funding from government sources (details on that to be published on NaturalNews shortly).

This was all admitted in a published paper called “U.S. reviews human trial participant protections.” (The Lancet, Volume 376, Issue 9757, Pages 1975 – 1976, Dec. 11, 2010).

This paper declares, “In a sign of just how thoroughly enmeshed in medical establishment approval the Guatemala study was, the IoM had to decline the assignment, citing “overlapping appointments” in the 1940s between individuals on an IoM subcommittee and the NIH Study Section on Syphilis. The fact-finding task has now been transferred to the bioethics committee.”

The IOM is an organization that promotes nutritional deficiencies, ignores the science on disease prevention with nutrition, and that was so involved in the illegal, government-run medical experiments on Guatemalan prisoners that it had to remove itself from the bioethics investigative committee appointed to investigate the matter.

The IoM is also largely funded by both military government interests (including funds from the Department of Defense, which we will explain later), pharmaceutical interests (it takes money from all the top Big Pharma companies) and top global elitists like Bill Gates who are openly calling for the use of vaccines to “reduce world population by 10 to 15 percent.”

New Survey Shows Unvaccinated Children Vastly Healthier – Far Lower Rates of Chronic Conditions and Autism

A new survey of 7724 participants shows unvaccinated children are healthier and have vastly fewer chronic conditions than the vaccinated. 

UPDATE 8 March 2012:

The survey is continually updated so we recommend you visit the source site [links below] if you want to see the updated data.  There is also a summary chart comparing vaccinated to unvaccinated children for various conditions on the site on the page found here.  Today numbers in the survey are 10921 participants.

What follows is the original text of this post on 26th August 2011.

You can find the up-to-date results of illnesses and diseases in unvaccinated children here in the results of the survey.

Full details of the survey appear below with graphs.  The results are subdivided into different age groups. Information about country, gender, age, age distribution, breastfeeding, preferred treatment can be found here

This is excellent work from an independent source.  The survey is conducted by www.impfschaden.info and the English version www.vaccineinjury.info.  The survey is originally published here The Health of Unvaccinated Children, Survey Results.

About twenty years ago in 1992 a survey by the New Zealand Immunisation Awareness Society found also that unvaccinated children are healthier than the vaccinated: Unvaccinated Children Are Healthier.

It is interesting neither the US National Institutes of Health [US$30.5 billion annual budget on medical research] nor the US Centers for Disease Control [US$11 billion budget annually] could find the time or money to fund this kind of research but instead waste US tax dollars on a great deal of pointless medical research and promotion of iatrogenic [man made] disease causing agents [modern drug company “treatments”].  Hardly surprising then that an extraordinary 115 page review was published in June 2007 by the US Senate on the US Centers for Disease Control:-

A review of how an agency tasked with fighting and preventing disease has spent hundreds of millions of tax dollars for failed prevention efforts, international junkets, and lavish facilities, but cannot demonstrate it is controlling disease.”  “CDC OFF CENTER“- The United States Senate Subcommittee on Federal Financial Management, Government Information and International Security, Minority Office , Under the Direction of Senator Tom Coburn, Ranking Minority Member, June 2007.

Oddly the anti-vaccine-safety lobby not only will not carry out studies of the health of unvaccinated children but they just don’t want the studies done. Which should be a strange thing because they all insist the vaccines are safe and effective.  But in the CHS article linked at the end of this paragraph we show they actively sabotage this kind of work for sport at the expense of vaccine injured children.  This shows anti-vaccine-safety blogger Dr David Gorski’s self-admitted “minions” openly boasting on his blog about sabotaging this new study.  That is a fraud by these cyber thugs and bullies on all the parents who provided genuine information and tells you all you need to know about the anti-vaccine-safety lobby.  These animals are nasty, just nasty [Text added 2nd Sept 2011 @1240 EDT & updated 20 Sept 2011 @ 06:40 EDT]:-  Unvaccinated Kids Healthier Study – Gorski & His Internet Bullies Admit Sabotage

The Health of Unvaccinated Children

Survey Results

The results of our survey with 7724 participants show that unvaccinated children are far less affected by common diseases. Due to the fact that the majority of children in the survey are between 0 and 2 years of age and some diseases generally do not appear in this age group, the results are subdivided into different age groups (click on the graphic). Information about country, gender, age, age distribution, breastfeeding, preferred treatment can be found here.

Atopic diseases among unvaccinated children

Asthma, hay fever and neurodermatitis are seen very frequently today. A recent German study with 17461 children between 0-17 years of age (KIGGS) showed that 4.7% of these children suffer from asthma, 10.7% of these children from hay fever and 13.2% from neurodermatitis. These numbers differ in western countries, i.e. the prevalence of asthma among children in the US is 6% whereas it is 14-16% in Australia (Australia’s Health 2004, AIHW).

The prevalence of asthma among  unvaccinated children in our study is 0.2%, hay fever 1.5% and neurodermatitis 2%.

According to the KIGGS study more than 40% of children between the ages of 3 and 17 years were sensitized against at least one allergen tested (20 common allergens were tested) and 22.9% had an allergic disease. Although we did not perform a blood test, less than 10% stated that their children had an allergy.

By clicking on the graphic you can see the age distribution of the selected diseases.

Click here to see graph in new window or to save the graph

ADS, Hyperactivity, Autism, Sleeping problems, concentration problems and migraine

ADS and Hyperactivity was only 1 and 2 %, the prevalence of ADHD in Germany is 7,9% and another 5,9% which were not yet diagnosed, but were borderline cases(KIGGS).

By clicking on the graphic you can see the age distribution of the selected diseases.

Click here to see graph in new window or to save the graph

There are also autism cases in unvaccinated children. However over 80% stated, that it is only a mild form or a high functioning form of autism. Among all participants there were 4 severe autism cases. .

Of these 4 children one tested very high for metals(mercury, aluminum, arsenic), in another case the mother was tested very high for mercury.

Otitis media, Sinusitis, Herpes, Warts, Polyps and fungal infections

KIGGS showed that 12.8% of the children in Germany had herpes and 11% suffer from otitis media (an inflammation of the middle ear). If you compare this to unvaccinated children you can see that herpes among unvaccinated children is very rare (less than 0.5%).

The prevalence of sinusitis in young children has gone up as high as 32% (Albegger KW. Banale Entzüngen der Nase und der Nasennebenhöhlen. In: Berendes J, Link JR, Zöllner F, eds. Hals, Nasen-,OhrenHeilkunde in Praxis und Klinik. Band I. Obere und untere Luftwege. Stuttgart: G Thieme Verlag, 1979: 11.1–11.32.)

In our suvey only 2% of the children have problems with sinusitis, in less than 1% it happened only once.

In young kids under the age of 3 warts are very rare. After the 3 years of age, however, the prevalence is rising. In the ages between 4 and 6 years, 5-10% of the kids have warts, in the age group 16-18, 15-20% have warts.(http://www.netdoktor.at/health_center/dermatologie/warzen.htm)

Only 3% of unvaccinated children in our survey have warts.

By clicking on the graphic you can see the age distribution of the selected diseases.

Click here to see graph in new window or to save the graph

Fine motor skill problems, dentification problems, growth pains and scoliosis

By clicking on the graphic you can see the age distribution of the selected diseases.

Click here to see graph in new window or to save the graph

Diabetes, Epilepsy and seizures, neurological and autoimmune diseases, thyroid disorders

The National Institutes of Health in the USA  states that 23.5 % Americans suffer from autoimmune disease. This is a prevalence of more than 7% of children.

Diabetes affects 0.2% of the children under 20 years of age  in the USA (National Diabetes Fact Sheet)

The KIGGS study showed prevalence of epilepsy with 3.6%, prevalence of Diabetes in Germany with 0.1% and diseases of the thyroid gland  with 1.7%.

By clicking on the graphic you can see the age distribution of the selected diseases.

Click here to see graph in new window or to save the graph

Quotes from parents about the state of health of their children

Lot of parents gave some additional information of their children. Here are some typical quotes:

I am one of 10 children from the same mother and father.  None of us were vaccinated. Our ages are 38-59. We were all allowed to have childhood diseases to boost our immune systems. Most of our children were not vaccinated either.  Most of all none of the non-vaccinated children in our family have major illness.”

I will put the health of my three unvaccinated children up against the health of a vaccinated child any day of the week and twice on Sunday.”

My 3 year old child is in a 5 year old class, and is even advanced for that grade.  She has not been near as sick as a lot of her friends.  She is considered very advanced for her age.  Her two oldest siblings had both been injured by vaccinations and have been recovering for the last 6.5 years.”

My two boys are both uncircumcised, unvaccinated, including no vitamin K shot at birth, and no PKU newborn blood screening, and no painful procedure of any kind.  I gave birth drug-free and naturally in an upright kneeling position, after walking throughout my entire labor and transition.  Both boys are extremely healthy, intelligent, kind, and beautiful.  I breastfed my older son until he turned 4 years, and I’m currently breastfeeding my 2 year old.”

My 3 vaccinated children were sick often during their first 2 years, suffered from ear infections repeatedly for which the doctor was constantly prescribing antibiotics, which would never work on the 1st round. They’d go through 3 separate rounds of antibiotics before the infection would be gone, meanwhile they’d develop diarrhea and candida diaper rash. They got every “bug” that was going around and strep and tonsillitis on several occasions. They all have skin conditions which the doctor has diagnosed as keratosis pylaris. My unvaccinated child has never been sick beyond a slight, short-lived cold. Never had an ear infection and has no skin issues either.”

We chose not to vaccinate for various reasons, and have never tried to create an antiseptic environment for the children. We live on a small mid-western farm and the children seldom wear shoes in the warmer months (warmer than freezing)so that is most of the time. They are subject to occasional cuts from various metals, glass, etc. and have not had any infections to speak of. Not only that, but they get bitten by various animals, cats, mice,(they’re always catching mice)garden snakes, and the like, insects of all kinds, with no adverse affects. All but the first were home-birth, all were breast fed, and none of the last 8 have ever seen a doctor, (or MacDonalds).”

I fully vaccinated his sister. She died at age 5 mos 14 days after suffering many symptoms of mercury poisoning including eczema, milk allergy and hypo tonic-hyporesponsive episodes as well as dilated pupils. Her death was labeled “SIDS”. I know it was vaccine induced. I also suffered a severe reaction to smallpox vaccine and have other family history of severe vaccine reactions. My unvaxed son has never needed an antibiotic, never had an ear infection, and has not seen a doctor since he was 2 and that was for an eye issue that resolved itself.”

He has never had an ear infection or serious illness that required medication and he turned 2 in Dec 2010.  Vaccinated kids I know, including my 8 year old, were always sick.  Croup, eczema, RSV, Scarlet fever, strep, roseola, thrush, ashthma, food allergies, other allergies, and most of all ear infection after ear infection.  Comparing my daughter’s health records she was on antibiotics over 14 times her first 2 years of life.  She was SOOO sick all the time…doc said it was normal and compared to friends kids it was.  Everyone had sick kids ALL the time.  It is considered normal in kids under 3. She was not in daycare…so that argument of picking it up at daycare does not work.  I could not take her anywhere of she was sick.  Even pneumonia!

Amazed at the overall health compared to all the kids her age, she gets the same cold/flu and has extremely mild symptoms compared to the other kids who are experiencing severe infections resulting in urgent care visits and prescriptions. All of the milestones were met early is able to read words before 2 1/2 years of age.”

My father is a MD and when time came for my daughter vaccination he asked me for the schedule and after reading it recommended to me not to do it.I myself when kid, was asthmatic and my dad was worried about the effects of the vaccines on her. She is a super healthy teen, never has been on antibiotic, resists all flu season without a problem and her immune system is super strong. Her brother is just the same”

HERE ARE FURTHER DETAILED RESULTS

Click Graphs to Open Larger View in New Window

Survey Autism ADD Hyperactivity migraine sleep disorders in unvaccinated children

Sleep problems, extreme crying, ADHD, autism, migraines, concentration and sleep problems in unvaccinated children

The graphics below show the age distribution of the selected diseases. In the case of a missing bar chart, this means that there are no affected persons in this age group.

Survey Atopy in unvaccinated children

Atopy in unvaccinated children

The graphics below show the age distribution of the selected diseases. In the case of a missing bar chart, this means that there are no affected persons in this age group.

Survey Otitis sinusitis polyps herpes warts and dermatophytes in unvaccinated children

Otitis, sinusitis, polyps, herpes, warts and dermatophytes in unvaccinated children

The graphics below show the age distribution of the selected diseases. In the case of a missing bar chart, this means that there are no affected persons in this age group.

Survey Fine motor skill problems growth pains and disturbances dentification problems and Scoliosis in unvaccinated children

Fine motor skin problems, growth pains and disturbances, dentification problems and Scoliosis in unvaccinated children

The graphics below show the age distribution of the selected diseases. In the case of a missing bar chart, this means that there are no affected persons in this age group.

Survey Diabetes epilepsy neurological autoimmune and thyroid disorders in unvaccinated children

Diabetes, epilepsy(and non epileptic seizures), neurological, autoimmune  and thyroid disorders in unvaccinated children

The graphics below show the age distribution of the selected diseases. In the case of a missing bar chart, this means that there are no affected persons in this age group.

UK Guardian Newspaper Caught Falsifying the Historical Record of Vaccine-Caused-Autism

In a first for journalism, the UK’s Guardian national daily newspaper has been caught falsifying their own newspaper’s public record in a bid to airbrush the facts about vaccine-caused-autism.  Whilst some other media outlets have adopted the approach of ignoring the evidence and writing and broadcasting one-sided reports, this time The Guardian newspaper has been caught changing it.  The Guardian removed the evidence – gone without a trace – from their online newspaper.

Like many other papers, The Guardian allows readers to post comments on articles published in their online version.  On Saturday 6 August 2011 the paper published a commentary by Tracy McVeigh “Research linking autism to internet use is criticised“.  This was about a public row over claims by Lady Susan Greenfield that there is a link between the increase in autism and the increase in the use of the internet.  Greenfield is a medical academic and researcher on brain physiology, particularly on Parkinson’s and Alzheimer’s diseases.

Inevitably this attracted debate between commenters about the causes of autistic conditions.

The surprising part is what The Guardian did in response to postings of clear evidence of an admitted link between vaccines and autistic conditions.  They obliterated the posts as if they had never been made on their newspaper’s site.  There is no trace of the posts to be found.  They are just gone, barring a trace for one of them only – the first to be removed.  There was no justification for this and none has so far been provided despite having been requested.  The posts met the “Community Standards” whereas in contrast offensive comments from anti-vaccine safety campaigners are not removed.

The importance of this of course is that it underlines the points that:-

  • news media are intentionally covering up the public disaster where 1 in 64 British children [1 in 40 being British boys] have an autistic condition and 1 in 100 US children do also;
  • when they should instead report such a terrible thing fairly and campaign to do something about stopping this happening;
  • the evidence presented is so strong that a UK national newspaper cannot answer it and airbrushes it from its online pages.

What happened was that in response to numerous comments claiming vaccines are not implicated in causing autistic conditions CHS intervened.  CHS posted publicly made quotes and links to evidence confirming numerous US government agencies and officials have confirmed vaccines do cause autistic conditions.  These include:

  • Merck’s current Director of Vaccines Julie Gerberding when she was Director of the US Centers for Disease Control;
  • the US Health Resources Services Administration;
  • the US Federal Court;
  • the US Secretary of State for Health and Human Services.

The evidence and posts appear below in full.  These include posts noting the financial ties between the Guardian newspaper and medical publishers with undeclared substantial conflicting financial and business interests in the pharmaceutical industry.

In all four posts were removed.  Three without trace and one was removed with the incorrect claim left in its place that “This comment was removed by a moderator because it didn’t abide by our community standards.

If you want to make a difference then do something and write to the Guardian “Readers’ Editor” Nigel Willmott (nigel.willmott@guardian.co.uk) and ask him to tell you what The Guardian and its Board have to say about this and what they think their journalists should do if they caught another newspaper or broadcaster rewriting and publishing an adulterated history or engaging in misconduct.

______________________________________

THE FIRST POST REMOVED WITHOUT TRACE

ChildHealthSafety

8 August 2011 7:46AM

Here is a public opportunity to see The Guardian’s censorship of facts and evidence in action. The following facts are publicly documented yet The Guardian’s Comment is Free [LOL] censors removed it in its entiretly to airbrush the unpalatable facts from their agenda journalism. There was and could be no contravention of any Guardian “Community Standards” [well not official ones that is – only the ones that say the Guardian only publishes facts which fit its political agenda journalism and removes all others.

Tracey McVeigh’s article on Lady Susan Greenfield’s public unscientific comments about the causes of autistic conditions has provoked comment about the causes of autistic conditions.

In response to various comments we posted quotes from numerous US government officials and agencies with links to original sources on what causes autistic conditions. The Guardian censors removed the posting. There is no conspiracy theory here – only documented fact – and The Guardian does this kind of thing repeatedly.

This posting was made 7 August 2011 11:14AM and you can check out above that it was removed.

Floost 7 August 2011 9:49AM

I think arec pretty much nailed it ….. given ageofautism’s dangerous views on vaccination, I think you got off lightly.

So how about the views of 1) Merck’s current Director of Vaccines Julie Gerberding when she was Director of the US Centers for Disease Control 2) the US Health Resources Services Administration 3) the US Federal Court? 4) the US Secretary of State for Health and Human Services?

All have confirmed autistic conditions can be caused by vaccines.

GERBERDING:

“.. if you’re predisposed with the mitochondrial disorder, it can certainly set off some damage. Some of the symptoms can be symptoms that have characteristics of autism.

CNN – HOUSE CALL WITH DR. SANJAY GUPTA Unraveling the Mystery of Autism; Talking With the CDC Director; Stories of Children with Autism; Aging with Autism Aired March 29, 2008 08:30 ET

US HRSA:

[when confirming of the 1322 cases of vaccine injury compensation settled out of court by the US Government in secret settlements]:-

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.

US HRSA to reporter Sharyl Attkisson of CBS News 5th May 2008

US FEDERAL COURT
[PDD is the US term under DSM IV for ASD – Autistic Spectrum Disorder]:

“…… Bailey’s ADEM was both caused-in-fact and proximately caused by his vaccination. …… Furthermore, Bailey’s ADEM was severe enough to cause lasting, residual damage, and retarded his developmental progress, which fits under the generalized heading of Pervasive Developmental Delay, or PDD. The Court found that Bailey would not have suffered this delay but for the administration of the MMR vaccine, and that this chain of causation was a proximate sequence of cause and effect leading inexorably from vaccination to Pervasive Developmental Delay.

[Banks v. HHS (Case 02-0738V, 2007 U.S. Claims LEXIS 254, July 20, 2007).

US SECRETARY OF STATE FOR HEALTH AND HUMAN SERVICES:-

The Department for Health and Human Services conceded the Hannah Poling case – that Hannah’s autistic condition was caused by 9 vaccines [ie. not just the MMR] administered in one day. Last year the US Federal Court determined a settlement which reportedly amounts to US $ 20 million over Hannah Poling’s lifetime:

Court Awards Over $20 Million for Vaccine-Caused Autism PR Newswire (press release) – Sep 15, 2010

Family to Receive $1.5M+ in First-Ever Vaccine-Autism Court Award CBS News September 9, 2010

“Settlement reached in autism-vaccine case” September 10, 2010 By Carrie Teegardin The Atlanta Journal-Constitution.


THE SECOND POST REMOVED WITHOUT TRACE

ChildHealthSafety

8 August 2011 9:20AM

In our post above noting direct censorship of public facts by The Guardian perhaps we should have added “Follow the Money”.

GUARDIAN & BRITISH MEDICAL JOURNAL
Guardian partners with British Medical Journal Group for online first Tuesday 3 March 2009 00.00 GMT

“Derrick Malone, Guardian Product Manager said: “People naturally turn to the Internet when researching health issues and we were keen to provide our users with factual information they could trust to complement our extensive features on health issues. The pages were developed entirely in house by the GNM technology team in collaboration with BMJ Group.”

Rachel Armitage, Director, BMJ Evidence Centre said: “We’re pleased to partner with the Guardian and bring our knowledge to a wider audience. The information is based on our ‘Clinical Evidence’ product, which provides doctors with access to the very latest and most relevant medical knowledge and is used to make treatment decisions.”

BRITISH MEDICAL JOURNAL & DRUG INDUSTRY
The Editor in Chief of the British Medical Journal was forced to make an embarrassing correction regarding the BMJ’s own failures to disclose its conflicting financial interests in the drug industry.

Here is the correction forced ultimately by online criticism from New York charity The Alliance for Human Research Protection:-

“The BMJ should have declared competing interests in relation to this editorial by Fiona Godlee and colleagues (BMJ 2011;342:c7452, doi:10.1136/bmj.c7452). The BMJ Group receives advertising and sponsorship revenue from vaccine manufacturers, and specifically from Merck and GSK, which both manufacture MMR vaccines. For further information see the rapid response from Godlee (www.bmj.com/content/342/bmj.d1335.full/reply#bmj_el_251470). The same omission also affected two related Editor’s Choice articles (BMJ 2011;342:d22 and BMJ 2011;342:d378).

However, this also still fails to mention the most glaring conflict of all, which it all – BMJ’s business partnership with Merck through their information arm, Univadis (‘MSD signs partnership with BMJ group’).

THE THIRD POST REMOVED WITHOUT TRACE

ChildHealthSafety

9 August 2011 8:45AM

Artros @ 8 August 2011 9:32PM

Between the Internet, vaccines and dental amalgams, I think I’ve seen it all. Come on, man, vaccines? That’s like saying “influenza causes autism.”

Comments like this have been answered with quotes posted by us [with links to original publicly documented sources] but The Guardian removed them twice despite being in accordance with “Community Standards”. The second time there is no trace whatsoever of the original posting – The Guardian’s Comment is Free [LOL] removed it in its entiretly. This is an example of a national news media outlet using censorship to rewrite history and airbrushing facts from the record which directly contradict their strongly held personal beliefs.

The quotes were from 1) Merck’s current Director of Vaccines Julie Gerberding when she was Director of the US Centers for Disease Control 2) the US Health Resources Services Administration 3) the US Federal Court? 4) the US Secretary of State for Health and Human Services? All have confirmed autistic conditions can be caused by vaccines.

The second posting [8 August 2011 7:46AM] was removed with no trace of it ever having existed, whereas the position of the first posting can still be seen [7 August 2011 11:14AM].

We also added a posting [8 August 2011 9:20AM] with links to original sources showing the commercial and financial partnerships deals between The Guardian and The British Medical Journal and The British Medical Journal and the drug industry. That posting was removed without trace – no footprints, no traces, just gone.

So two of the three comments are gone and one has the following claiming without any truth that:

“This comment was removed by a moderator because it didn’t abide by our community standards.”

Frankly, normal sensible intelligent people may find such behaviour of The Guardian a little troubling.

If these comments were removed without trace, how much of what The Guardian publishes online is a moving target – being removed, deleted, altered and/or added to in order to write history according to what the Guardian wants it to be instead of what it is? Very Pravda.

And “Community Standards”? Please, no laughter at the back of class:-

10. The platform is ours, but the conversation belongs to everybody. We want this to be a welcoming space for intelligent discussion, and we expect participants to help us achieve this by notifying us of potential problems and helping each other to keep conversations inviting and appropriate. If you spot something problematic in community interaction areas, please report it. When we all take responsibility for maintaining an appropriate and constructive environment, the debate itself is improved and everyone benefits.

In short:

– If you act with maturity and consideration for other users, you should have no problems.

British journalism at its finest and no Rupert Murdoch to blame it on.

Andrew Wakefield On Jon Rappoport Show – Listen on mp3

The Jon Rappoport Show – 27 July 2011

Jon interviews world-famous Dr. Andrew Wakefield, who was stripped of his medical license for suggesting that vaccines could do harm. What forces are aligned against him?

Including the Murdoch, News Corporation, News International & British Medical Journal connections.

British Medical Journal Fraud Allegations – Truth Laid Bare – Summary Re Autism & Dr Wakefield

For those familiar with the British Medical Journal’s allegations of fraud against Dr Andrew Wakefield, here is a summary of the main points for reference and assistance to cut it down to easily manageable proportions.

For those not familar, read these CHS posts for background and detail:-

The BIG Lie – Wakefield Lancet Paper Alleged Fraud – Was Not Possible For Anyone To Commit

The BIG Lie II – British Medical Journal Caught Out – Wakefield Fraud Allegations Based On Incorrect Information

Summary of British Medical Journal/Wakefield Fraud Allegations – Truth Laid Bare

Contrary to the key aspect of the BMJ Editors’ allegations that Andrew Wakefield changed prior medical histories of the children to fabricate a new finding of developmental disorders related to bowel conditions in children, Wakefield did not originate the data reported in the 1998 Lancet paper.

To allege fraud requires a comparison between the information originated by the clinicians and what the Lancet paper says.

The BMJ and their commissioned author Mr Deer did not do that.

They also changed what the paper was reporting to fit what they wanted it to say to allege fraud.

They cherry-picked information from family doctor records and the GMC hearings to allege there were discrepancies.

The Lancet paper explicitly reports on

12 children … with a history of normal development followed by loss of acquired skills, including language, together with diarrhoea and abdominal pain”.

Deer and the BMJ changed this to reporting 12 children:

  • 1) with autism, who regressed,
  • 2) had “non-specific colitis”; and,
  • 3) whose symptoms of autism were first indicated within 14 days of the MMR vaccine.

But the Lancet paper was not reporting that. So what Deer and the BMJ did was to 1) select data 2) which would not match what they claimed the Lancet paper reported.

For example:

  • 1) only 9 of the 12 were diagnosed with an autistic condition;
  • 2) most had non specific colitis [11/12] but not all;
  • 3) most regressed but the first indications of a behavioural change were not documented for all so the paper could clearly not report first signs of behavioural changes occurring within 14 days.

The BMJ Editors and their author Brian Deer also did not have important information, such as the final assessments of the bowel conditions of the 12 children investigated within the Royal Free by the clinicians – not Wakefield – showing most diagnosed with non specific colitis [11/12].  So the numbers of children with diagnoses which BMJ/Deer reported were wrong.

Nor did they have the “Personal Child Health Records” documenting whether a child is developing within the “normal range” of development or not.

These aspects of information not available in the GMC proceedings were dealt  with and mentioned in the GMC transcripts but Deer and BMJ seem to have “overlooked” them.

The 1998 Lancet paper was drafted by Dr Wakefield but it reported the findings of the 12 expert specialist Royal Free Hospital clinicians. The various versions were circulated to the other 12 authors for comment, amendment and approval.  Wakefield was a researcher and not an investigating clinician.

In particular, the medical histories of the 12 children reported in the paper were taken by Professor John Walker-Smith of The Royal Free Hospital, London, England.  The diagnoses of bowel conditions of the 12 children were made by Dr Dhillon, with consideration and comment by his colleagues.  The diagnoses of autistic and other conditions in 8 children were made by Dr Berlowitz and in 4 cases by independent external medical experts not connected with The Royal Free Hospital.

The BMJ engaged in blatant cherry-picking. 

  • One month before her MMR vaccine Child 8 was recorded by an independent specialist developmental pediatrician [unconnected with The Royal Free Hospital] as within the normal range of development aged 18 months.  One month after the MMR vaccine, aged 20 months, the same pediatrician records she was functioning at the age of 12 months.  She regressed 8 months in the space of 1 month following the MMR vaccine.
  • Child 1’s mother reported he was having trouble hearing before MMR.  The BMJ and their author Brian Deer claim this was a sign of autism.  The family doctor however recorded Child 1 had a discharge from his ear, indicating an ear infection.  How did the BMJ and their peer reviewers failed to notice that?  Or was it they did not care as long as they could accuse Andrew Wakefield of fraud?

Bizarrely, to cover up the failure over the Personal Child Health Records the BMJ’s author Deer claimed only a negligent doctor would refer to them and scathingly referred to them as “baby books”. The fact is he had never seen them. More importantly, it is clear they these “experts”, he and the BMJ, did not know these are “prospective developmental records” and were cited specifically in the 1998 Lancet paper as a source of information for clinical and developmental histories reported.  But still thought themselves “expert” enough to allege fraud against Andrew Wakefield.

The PCHR is an 81 page book issued by the NHS to every UK parent of a newborn child to capture information up to the age of 5 years recorded by health visitors, midwives, nurses, doctors and parents to ensure the health and normal development of children in the UK.  It is the obvious place of first reference when checking a developmental history.  Neither Deer nor the BMJ even noticed the omission.

And that is how you end up with a Table like this to claim the children did not have the symptoms the BMJ claimed incorrectly that the Lancet paper said they had [published in the BMJ, January 6. 2011 – Click on image to open in new window]:-

BMJ & Its Editors’ Failures to Declare Conflicting Drug Industry & Vaccine Manufacturer Financial Interests.

The BMJ Editors’ subsequent Conflict of Interest correction was no ordinary matter – they failed to disclose material conflicting interests, it involved three senior editors of the BMJ and it relates to amongst other matters, ongoing business and financial partnerships between the BMJ and the pharmaceutical industry.

The correction was forced finally by explicit criticism posted in the BMJ electronic responses from the US New York based charity the Alliance for Human Research Protection [AHRP].  This was in addition to public outcry in a deluge of emails from parents of children with autistic conditions in the USA and elsewhere.

It should have gone further.  A clear statement should have been made in the next available journal to follow and it should be presented in every printed edition and on the home page of the online edition for every edition.

They tried to minimise their very serious error by some circumspect reasoning described by AHRP as “startling”.  The BMJ editors claimed We didn’t declare these competing interests because it didn’t occur to us to do so. Mildly put that shows that editorial diligence and forethought was lacking.

That in itself should have been enough to retract the journal articles … that was their contention with Andrew Wakefield.

Couple that with witness and institutional conflicts of interest not revealed or elaborated to the general public and the possible ethical breaches of patient confidentiality then one wonders how this still remains in the public arena.

What Does This Mean For You, Your Children, Your Family, British Doctors And The Wider Medical Professions

You cannot trust your doctor and you cannot believe him or her.  When you visit your doctor he or she is part of this.  He or she is sitting back and letting this go on under his or her nose without complaining – keeping silent – saying nothing.  He or she is the person prescribing for you and your children and families drug industry products which kill and injure because they have not been tested properly like Vioxx and vaccines and/or because they are useless, but he or she is happy to enjoy the money earned doing that.  He or she is the person who gets your private medical information but you cannot trust them with it because he or she sits back and does nothing when children’s medical records are illegally disclosed and used by a journalist who then writes about them in the British Medical Journal.

He or she is a member of The British Medical Association, the doctors’ trades union, or one like it outside the UK.

The BMA is a symbol of our morally and politically sick society.

The BMA sits back and takes the substantial profits of wrongdoing from its own journal, the British Medical Journal.  The BMA’s official line is that it does not control the running of the BMJ and its stable of other journals and pretends to the public and patients it can do nothing about it.  The BMA is a politically powerful organisation with the British government but pretends it cannot control its own house journal mailed every week to all of its members.  But if the BMA cannot control its own house journal, guess who can exercise control over the BMA?  Yep, BMJ Editor-in-Chief Dr Fiona Godlee is a Chief Officer of the BMA: [BMA Chief Officers]. Her name appears first on the BMJ Editorial falsely accusing Dr Andrew Wakefield of fraud.

Over and above all that, the BMA is a trades union.  It does not represent you or your children or your wider family when it comes to health.  It is there to get and keep money in the pockets of its members, and it looks like when it comes to the BMJ and the drug industry, it really does not care how it does that.

And when the BMA makes public statements on health matters and lobbies the British government for what it wants, you can be sure that is not done with you the patient, your children and family in mind, even if that is claimed to be the case.

The current Chairman of the BMA is Professor David Haslam and the Chairman of The BMA Council is Dr Hamish Meldrum: BMA Chief Officers.

Dr Meldrum’s résumé says:

… he is keen to ensure that both the organisation and the profession are well prepared to meet the challenges of ensuring that doctors are supported and fairly rewarded in delivering the highest possible quality care to their patients and that the NHS remains true to its founding values and principles in an increasingly complex environment.

His interests, outside medicine and medical politics, when he has time, include sport (watching lots and participating in keep fit, tennis, swimming and dormant golf), hill-walking, photography, music (quite varied tastes), cooking (also varied tastes) and wine.

It does not say anything about maintaining the reputation of the British medical profession for high standards of ethics and probity. Enjoy your “dormant golf” Dr Meldrum.  With all those outside sporting interests Dr Meldrum’s time is clearly taken up with a lot of balls.  With so many in the air, has he dropped the BMJ’s?

Human DNA in Vaccines Linked to Autism

CHS brings you another site to consider subscribing to, that of Dr Mercola in the USA which carries many articles of a broad interest in medical matters challenging what appears to be the medical professions’ mindless following of a herd approach to “consensus” in medicine: Dr Mercola.com.

Here is an extract from an example of a Mercola.com article worth reading:

One of the Most Inexcusable Vaccine Revelations of All… Posted By Dr. Mercola | July 10 2011

Former drug company scientist Helen Ratajczak recently created a firestorm of debate from all sides of the vaccine-autism issue when she published her comprehensive review of autism research. This is a massively important study, for more than one reason. One element brought to light that has managed to stay well below the radar is the use of aborted embryonic cells in vaccine production.

CBS News recently reported:

“Ratajczak reports that about the same time vaccine makers took most thimerosal out of most vaccines (with the exception of flu shots which still widely contain thimerosal), they began making some vaccines using human tissue.

Ratajczak says human tissue is currently used in 23 vaccines. She discusses the increase in autism incidences corresponding with the introduction of human DNA to MMR vaccine, and suggests the two could be linked.”

Read on here for more, including Dr Mercola’s commentary:-

One of the Most Inexcusable Vaccine Revelations of All… Posted By Dr. Mercola | July 10 2011

EU Takes Emergency Measures Over Glaxo’s ‘Flu Vaccine – Causes Narcolepsy in Children

GlaxoSmithKline’s ‘Flu vaccine causes four-fold increase of cases of narcolepsy in children and adolescents (below 20 years of age) who received Pandemrix compared with unvaccinated people  of the same age according to preliminary results of the Swedish registry study from October 2009 to December 2010 on Pandemrix.  

Clearly this vaccine was not properly tested, like many other childhood vaccines.

Full Text of EMEA news release 15 April 2011 below.  Download links below to French and Swedish agencies’ reports on the narcolepsy problem.

And do vaccines cause autistic conditions? If you read nothing else we strongly recommend you read this: PDF Download – Text of email from US HRSA to Sharyl Attkisson of CBS News].  In it the US Health Resources Services Administration [HRSA] state to CBS News reporter Sharyl Attkisson

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.

Despite all the lies and deceit by health official worldwide, the question “do vaccines cause autism” was answered when the Hannah  Poling story broke in the USA [see CHS article here].  Hannah developed an autistic condition after 9 vaccines administered the same day.  Under the media spotlight numerous US health officials and agencies conceded on broadcast US nationwide TV news from CBS and CNN. In the US Federal Court children have been compensated after findings they developed autism and other injuries. Full details with links to the original sources can be found in this CHS article: Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines. [Blue Text added 10 April 2011]

_____________________________

News Release

European Medicines Agency recommends interim measures for Pandemrix – 15/04/2011

Updated prescribing advice highlights preliminary results from epidemiological studies on narcolepsy; further research needed

The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended that the product information for Pandemrix should be amended to advise prescribers to take into account preliminary results from epidemiological studies on Pandemrix and narcolepsy, and to perform an individual benefit-risk assessment when considering the use of Pandemrix in children and adolescents. This is an interim measure pending the outcome of the European review, expected to conclude in July 2011.

The CHMP reviewed all available data, including new findings from Sweden and France on the suspected link between narcolepsy in children and adolescents and Pandemrix. The CHMP concluded that, following the earlier results of an epidemiological study from Finland, the new evidence strengthened the signal in children and adolescents, but that the data had methodological limitations. The relationship between Pandemrix and narcolepsy is still under investigation.

Preliminary results of the Swedish registry study from October 2009 to December 2010 on Pandemrix vaccination and the risk of narcolepsy indicates a four-fold increase of cases of narcolepsy in children and adolescents (below 20 years of age) who received Pandemrix compared with unvaccinated people of the same age. The additional risk corresponds to an additional 3-4 narcolepsy cases per 100,000 vaccinated subjects. These results are broadly in line with the study results from Finland indicating an association between Pandemrix and narcolepsy in children and adolescents. The study did not identify any increased risk in adults. The CHMP concluded that the study was well conducted, although it has inherent limitations.

An analysis of narcolepsy reports in France provides some further evidence.

The lack of a clear increase in reports of narcolepsy following Pandemrix in other EU and non-EU countries may point towards the influence of other unknown factors affecting the trend seen in some countries. Also, there is currently no clearly identified biological plausibility for an association between Pandemrix and narcolepsy, and further non-clinical studies, especially in the juvenile setting, are needed.

The CHMP considers it important to gather more data on the use of Pandemrix and related vaccines in a variety of countries to further assess this concern. A variety of research efforts are now ongoing. These include an epidemiological study of narcolepsy and pandemic vaccines conducted by the European Centre for Disease Prevention and Control (ECDC) through a network of research and public health institutions (VAESCO) in nine European Union Member States, and an epidemiological study conducted by Glaxo Smith Kline (the marketing authorisation holder of Pandemrix) in Canada. Preliminary results of the VAESCO study and of the Canadian study are expected by July 2011.

The CHMP is working with experts from across the EU to assess the possible safety concern and any impact on the benefit-risk balance of Pandemrix. The CHMP plans to hold an expert meeting with participation of international experts, the World Health Organization (WHO) and ECDC.

The European Medicines Agency will provide updates as new information becomes available.

Notes

  • The exact wording to be included in the Pandemrix product information reads as follows:“Preliminary reports form epidemiological studies in two countries (Sweden and Finland) have indicated a 4-9-fold risk increase of narcolepsy in vaccinated as compared with unvaccinated children/adolescents, corresponding to an absolute risk increase of about three to four additional cases in 100 000 vaccinated subjects. This risk increase has not been found in adults (older than 20 years). Similar epidemiological studies have not yet been conducted in other countries.The relationship between Pandemrix and narcolepsy is still under investigation.When considering the use of Pandemrix in children and adolescents, an individual benefit risk assessment should be performed taking this information into account.”
  • Narcolepsy is a rare sleep disorder that causes a person to fall asleep suddenly and unexpectedly. Its precise cause is unknown, but it is generally considered to be triggered by a combination of genetic and environmental factors. Narcolepsy occurs naturally at a rate of around 1 case per 100,000 people every year.
  • Pandemrix, an (H1N1) v influenza vaccine, has been authorised since September 2009, and was used during the 2009 H1N1 influenza pandemic in at least 30.8 million Europeans.
  • The H1N1 influenza strain continues to be the predominant strain in this season.
  • The review of Pandemrix and the occurrence of cases of narcolepsy was initiated at the request of the European Commission under Article 20 of Regulation (EC) No 726/2004, on 27 August 2010, following an increased number of reports on narcolepsy in Finland and Sweden. Related press releases dated 27 August 2010, 23 September 2011 and 18 February 2011 are available on the Agency’s website.
  • The report from the Swedish registry study can be found on the website of the Swedish Medicines Agency (MPA).
  • The report from the French observed expected study can be found on the website of the French Medicines Agency.
  • More information about the network of research, public-health institutions and regulatory agencies VAESCO, funded by the European Centre for Disease Prevention and Control, can be found on its website.

News Stories From Google

European Regulators: Weigh Potential Narcolepsy Risk of Glaxo’s Pandemrix

Wall Street Journal (blog) – Katherine Hobson – ‎14 hours ago‎
Since last August, European regulators have been investigating reports that GlaxoSmithKline’s H1N1 vaccine, Pandemrix — which isn’t approved for use in the US — may be tied to the sleeping disorder narcolepsy in some children and

EU agency flags narcolepsy risk on GSK flu shot

Reuters – ‎17 hours ago‎
By Ben Hirschler LONDON (Reuters) – European regulators have recommended changes to the product label for GlaxoSmithKline’s pandemic flu vaccine Pandemrix to highlight the potential risk of narcolepsy in children or adolescents.

EU Panel Recommends Pandemrix Product Information Be Amended

Wall Street Journal – Ian Walker – ‎21 hours ago‎
LONDON (Dow Jones)–The Committee for Medicinal Products for Human Use, or CHMP, said Friday it has recommended that the product information for Pandemrix (Influenza vaccine (H1N1)) (split virion, inactivated, adjuvanted), from GlaxoSmithKline

Glaxo Pandemic Flu Vaccine’s Narcolepsy Risk Highlighted

Fox Business – ‎19 hours ago‎
By Sten Stovall LONDON -(Dow Jones)- European regulators have recommended changes to the product label for GlaxoSmithKline PLC’s (GSK) pandemic flu vaccine Pandemrix to reflect a potential higher risk of the sleeping disorder narcolepsy in children or

European Medicines Agency Recommends Interim Measures For Pandemrix

Medical News Today (press release) – ‎20 hours ago‎
The European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP) has recommended that the product information for Pandemrix should be amended to advise prescribers to take into account preliminary results from epidemiological


Anti-Vaccine-Safety Blogs Desperate Over Thorsen/US CDC Autism Research Fraud

The rabid anti-vaccine-safety loons on Kev Leitch and Matt’s anti-vaccine-safety blog LeftBrainRightBrain have desperately republished a list of studies compiled by the American Association of Pediatrics in a vain attempt to counter the damaging revelations of the alleged fraud by autism-vaccine researcher Poul Thorsen: [US Prosecutors Seek Extradition of Madsen MMR/Autism Denmark Study Author for US$1m MMR & Mercury Autism Research Fraud]

LBRB and the AAP claim the published studies are evidence there is no causal association between vaccines and autistic conditions: [pdf download  AAP List of Studies]

Unfortunately for the AAP and LeftBrainRightBrain, the very first study cited in the AAP list is the Budzyn study from Poland.  It is a study even LeftBrainRightBrain admitted when originally published is junk research.  This also raises serious questions about the reliability of the AAP and their ability to discern valid from invalid research. The Budzyn paper is Lack of Association Between Measles-Mumps-Rubella Vaccination and Autism in Children: A Case-Control Study Mrozek-Budzyn D, Kiełtyka A, Majewska R. Pediatr Infect Dis J. 2010 May;29(5):397-400.

This is what LBRB said about the Budzyn dud paper when it first came out:-

To be honest, I don’t think these results are consistent with previous, large population studies of MMR and autism. An odds ratio of 0.17 (meaning you are six times more likely to be autistic if you didn’t get the MMR) should have been picked up.”

And the LBRB reviewer “Sullivan” added in the comments:-

If you look at only the kids who were never vaccinated for Measles—8 children (8%) in the autism group were never vaccinated for MMR. Only 1 in the control group (0.5%). If one were to use those numbers alone, the uncorrected “odds” of autism associated with MMR would be 16:1.”

Additionally, all the papers are cited as evidence of no association between MMR vaccination and autistic conditions.  But we now know as a result of admissions by US Government Officials and decisions of the US Federal Court that it is not just MMR vaccine but all vaccines which can and do cause autistic conditions.

If you read nothing else we strongly recommend you read this: PDF Download – Text of May 5th 2008 email from US HRSA to Sharyl Attkisson of CBS News].  In it the US Health Resources Services Administration [HRSA] state to CBS News reporter Sharyl Attkisson:

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.

Despite all the lies and deceit by health official worldwide, the question “do vaccines cause autism” was answered after the Hannah  Poling story broke in the USA in February 2008 [see CHS article here].  Hannah developed an autistic condition after 9 vaccines administered the same day.  Under the media spotlight numerous US health officials and agencies conceded on broadcast US nationwide TV news from CBS and CNN. Full details with links to the original sources can be found in this CHS article: Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines. [Blue Text added 10 April 2011]

US Prosecutors Seek Extradition of Madsen MMR/Autism Denmark Study Author for US$1m MMR & Mercury Autism Research Fraud

Reuters reports that US prosecutors have indicted and seek the extradition of Aarhus University, Denmark’s MMR/mercury & autism researcher Poul Thorsen 49, on  13 counts of wire fraud and nine counts of money laundering.  This relates to monies paid to Thorsen by the US Centers for Disease Control including for research into the relationship between autism and exposure to vaccines.    Thorsen used the stolen money to buy a home in Atlanta, a Harley Davidson motorcycle and two cars, prosecutors said.

Denmark scientist accused of stealing autism research money.[ATLANTA | Wed Apr 13, 2011 7:35pm EDT]

[Read more: Dane indicted for defrauding CDC | Atlanta Business Chronicle ]

The real question is when will US prosecutors investigate the fraudulent commissioning and funding by CDC officials of studies they knew would produce the result they wanted.  An example is the Tozzi paper reported by CHS here: US Research Fraud, Tax Dollars And Italian Vaccine Mercury Study

What Did Thorsen Do?

Thorsen was a visiting researcher at the Atlanta-based CDC in the 1990s who obtained US$11m in research grants for two Danish government agencies.  Thorsen was in charge of administering the research funds to study the relationship between autism and exposure to vaccines.   It is alleged Thorsen submitted false invoices and arranged for Aarhus University where he was employed to transfer the funds to his personal account at the CDC Federal Credit Union in Atlanta.  It is said the university thought it was transferring the funds to a CDC account.

Here you can download the full set of US Grand Jury charges: CRIMINAL   INDICTMENT: UNITED   STATES  OF  AMERICA v. POUL  THORSEN NO·1:  11- C R – 194 [Blue Text Added 19 April 2011]

Thorsen’s Questionable Research

Thorsen was an author of the now notorious US CDC funded New England Journal of Medicine Madsen study of 500,000 Danish children which was used worldwide to claim there was no relationship between MMR vaccine and autistic conditions.  Thorsen was also involved in publishing studies claiming there was no link between the mercury additive thiomersal in vaccines, autistic conditions and developmental disorders in children.

Numerous irregularities were subsequently revealed in the Madsen study and rates of autistic conditions in fact rose in Denmark contrary to the claims of the authors of the Madsen study:  A Population-Based Study of Measles, Mumps, and Rubella Vaccination and Autism Kreesten Meldgaard Madsen, M.D., Anders Hviid, M.Sc., Mogens Vestergaard, M.D., Diana Schendel, Ph.D., Jan Wohlfahrt, M.Sc., Poul Thorsen, M.D., Jørn Olsen, M.D., and Mads Melbye, M.D.   N Engl J Med 2002; 347:1477-1482 November 7, 2002.

According to US vaccine safety organisation Safeminds some of the research Thorsen engaged in, substantial numbers of diagnosed autism cases disappeared annually from the data Thorsen and colleagues relied on.  Thorsen engaged in email correspondence with the US Centers for Disease Control about how to produce results which showed a more favourable safety profile for vaccines.  SafeMinds is calling for an independent federal investigation of these studies for data manipulation and scientific misconduct.

From August to October of 2003, three articles on the autism-mercury controversy were published in close succession, all of which used data from a Danish registry for psychiatric research to assess the relationship between autism trends and the use of thimerosal. SafeMinds accessed the registry at the time and reported that a large percentage of diagnosed autism cases are lost from the Danish registry each year and that most of those lost cases were older children. Since the studies were  based on finding fewer older thimerosal-exposed children than younger unexposed children, the validity of their conclusion exonerating thimerosal in autism was questionable and likely a result of missing records rather than true lower incidence rates among the exposed group.

In addition, internal emails obtained via FOIA document discussion between the Danish researchers and Thorsen which acknowledge that the studies did not include the latest data from 2001 where the incidence and prevalence of autism was declining which would be supportive of a vaccine connection.

The emails also include requests from Thornsen to CDC asking that the agency write letters to the journal Pediatricsencouraging them to publish the research after it had been rejected by other journals.

A top CDC official complied with the request sending a letter to the editor of the journal supporting the publication of the study which they called a “strong piece of evidence that thimerosal is not linked to autism.”

Further background information on these studies, the charges against Dr. Thorsen, and documents obtained through the Freedom of Information Act that support SafeMinds’ concerns are available on their website, www.safeminds.org.

Similarities to the Professor Christopher Gillberg Scandal

The Thorsen affair has undertones of the Gillberg scandal. [NB. The “editors” of Wikipedia medical topics have ensured the following historical data is not readily available to readers.]

Swedish psychiatrist and autism researcher Professor Christoper Gillberg was a scientific board member of US organisation Cure Autism Now, a professor of child and adolescent psychiatry at Gothenburg University in Gothenburg, Sweden, and an honorary professor at the Institute of Child Health (ICH), University College London.  He was a member of and advised numerous boards responsible for providing research funding.

Gillberg destroyed 100,000 pages of research material filling 22 metres of shelf space on a 25 year study when ordered by a Swedish Court to make it available for scrutiny in the light of suspected fraudulent scientific research.  The study was a 25-year follow-up of 42 children diagnosed as having a condition invented by Gillberg called “DAMP” [Deficits in attention, motor control and perception]. DAMP was roundly criticised by English psychiatrist Professor Michael Rutter in expert Court evidence.   Gillberg was already notorious for admitting privately his children had not been vaccinated, while declaring no link between vaccines and autism.

On the basis of this study, 3,000 Swedish children were prescribed amphetamines (Ritalin) and Gillberg and his colleagues argued that another 70,000 children were in need of it.  Amphetamines can have serious adverse effects.

Leif Elinder, a paediatrician in Uppsala and Eva Kärfve, a sociologist at the University of Lund identified unusual features of Gillberg’s study including:

  • Nearly all the patients were recorded as attending during the study for comprehensive examinations but received no diagnosis or treatment;
  • the dropout rate of the study [3 out of 42] was very low, when expected to be high in such a study covering 25 years;
  • the number of participants appeared to have increased over the course of the study;
  • DAMP, like autism, affects far more boys than girls. However, while more than half of the control group consisted of girls, most of whom came from stable families and prosperous homes, 75% of the DAMP children were boys from dysfunctional families in run-down areas with poor housing;

Details of papers published by Poul Thorsen can be found with the following Google search.

_______________________

CLICK HERE FOR GOOGLE SCHOLAR SEARCH – AUTHOR P THORSEN

Following are 1st 100 hits.

[PDF] from safeminds.org…, D Schendel, J Wohlfahrt, P Thorsen… – New England Journal …, 2002 – nejm.org
We conducted a retrospective cohort study of all children born in Denmark from January 1991
through December 1998. The cohort was selected on the basis of data from the Danish Civil
Registration System, which assigns a unique identification number to every live-born
Cited by 383Related articlesBL DirectAll 26 versions

[HTML] from oxfordjournals.org…, E Agerbo, D Schendel, P Thorsen… – American Journal of …, 2005 – Oxford Univ Press
Research suggests that heredity and early fetal development play a causal role in autism. This
case-control study explored the association between perinatal factors, parental psychiatric
history, socioeconomic status, and risk of autism. The study was nested within a cohort of
Cited by 182Related articlesAll 15 versions

[PDF] from pkids.org…, MB Lauritsen, CB Pedersen, P Thorsen… – Pediatrics, 2003 – Am Acad Pediatrics
Objective. It has been suggested that thimerosal, a mercury-containing preservative in
vaccines, is a risk factor for the development of autism. We examined whether discontinuing
the use of thimerosal-containing vaccines in Denmark led to a decrease in the incidence
Cited by 148Related articlesBL DirectAll 33 versions

MJ Silverberg, P Thorsen, H Lindeberg… – Obstetrics & …, 2003 – journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. Skip Navigation Links Home > April
Cited by 125Related articlesAll 8 versions

P Thorsen, IP Jensen, B Jeune, N Ebbesen… – American journal of …, 1998 – Elsevier
Attempts to identify infections in the lower genital tract in women as one of the causes of pathologic
pregnancy outcome have been made throughout several decades. Recently, efforts have been
concentrated on the condition of BV as described by Amsel et al. 5 The diagnostic criteria
Cited by 97Related articlesBL DirectAll 4 versions

[HTML] from endojournals.orgK Erickson, P Thorsen, G Chrousos… – Journal of Clinical …, 2001 – Endocrine Soc
Increased CRH secretion by the placenta of pregnant women has been associated with preterm
birth. Certain indices of risk, both medical and psychosocial in nature, have been linked to preterm
delivery. Levels of total, bound, and free CRH, CRH-binding protein (CRH-BP), and
Cited by 80Related articlesBL DirectAll 5 versions

[HTML] from clinchem.orgK Skogstrand, P Thorsen… – Clinical …, 2005 – Am Assoc Clin Chem
Background: Inflammatory reactions and other events in early life may be part of the etiology
of late-onset diseases, including cerebral palsy, autism, and type 1 diabetes. Most neonatal screening
programs for congenital disorders are based on analysis of dried blood spot samples
Cited by 75Related articlesBL DirectAll 5 versions

C Floridon, CH Jensen, P Thorsen… – …, 2000 – Wiley Online Library
Abstract Fetal antigen 1 (FA1) is a circulating EGF multidomain glycoprotein. FA1 and its
membrane-associated precursor is defined by the mRNAs referred to as delta-like (dlk), preadipocyte
factor 1 (pref-1) or zona glomerulosa-specific factor (ZOG). Using a polyclonal antibody
Cited by 64Related articlesBL DirectAll 4 versions

…, P Thorsen, A Curry, P Sandager… – Acta obstetricia et …, 2005 – Wiley Online Library
Among symptomatic women, the likelihood ratio (LR+) for the prediction of PTD was found to
be greater than 10 using amniotic fluid (AF) interleukin-6 (IL-6), AF Ureaplasma urealyticum,
as well as a multi-marker consisting of cervical IL-6, cervical IL-8, and cervical length
Cited by 55Related articlesAll 7 versions

IP Jensen, P Thorsen, B Jeune… – … of Obstetrics & …, 2000 – Wiley Online Library
Objectives To estimate the incidence of human parvovirus B19 among pregnant women before
and during an epidemic, to elucidate possible sociodemographic and medical risk factors during
pregnancy and to estimate the association between parvovirus B19 infection and
Cited by 53Related articlesBL DirectAll 4 versions

…, KM Madsen, J Wohlfahrt, P Thorsen… – JAMA: the journal of …, 2004 – Am Med Assoc
Author Affiliations: The Danish Epidemiology Science Centre, Department of Epidemiology and
Social Medicine, Aarhus University, Aarhus (Drs Vestergaard, Madsen, and Olsen), The Danish
Epidemiology Science Centre, Department of Epidemiology Research, Statens Serum
Cited by 51Related articlesBL DirectAll 6 versions

IP Jensen, P Thorsen… – Lancet, 1997 – ncbi.nlm.nih.gov
1. Lancet. 1997 Feb 1;349(9048):329-30. Sensitivity of ligase chain reaction assay of urine from
pregnant women for Chlamydia trachomatis. Jensen IP, Thorsen P, Møller BR. Comment in: Lancet.
1997 Apr 5;349(9057):1024-5. Lancet. 1998 Jan 31;351(9099):341-2. Lancet.
Cited by 48Related articlesBL DirectAll 6 versions

GB Hvilsom, P Thorsen, B Jeune… – Acta obstetricia et …, 2002 – Wiley Online Library
Methods. The present study is a prospective nested case-control study including 84
singleton, preterm deliveries (cases) and 400 singleton, term deliveries (controls), based at the
Odense University Hospital, Denmark. These cases were identified from a cohort of 2846
Cited by 43Related articlesBL DirectAll 8 versions

[HTML] from shouxi.net…, M Vaeth, E Ernst, LF Nielsen, P Thorsen – Pediatrics, 2006 – Am Acad Pediatrics
METHODS. A population-based, cohort study, including all live-born singletons and twins born
in Denmark between January 1, 1995, and December 31, 2000, was performed. Children conceived
with in vitro fertilization (9255 children) were identified through the In Vitro Fertilization
Cited by 42Related articlesBL DirectAll 8 versions

…, A Schuchat, P Thorsen – Mental retardation and …, 2002 – Wiley Online Library
Cerebral palsy is the most common neuromotor developmental dis- ability of childhood, affecting
as many as 8,000 to 12,000 children born in the US each year (corresponding to a prevalence
rate of between 2 and 3 per 1000 children). Recent improvements in neonatal care have
Cited by 42Related articlesBL DirectAll 3 versions

[PDF] from dbac.dkCS Benn, P Thorsen, JS Jensen, BB Kjoer… – Journal of allergy and …, 2002 – dbac.dk
Background: Infants with wheezing and allergic diseases have a microflora that differs from that
of healthy infants. The fetus acquires microorganisms during birth when exposed to the maternal
vaginal microflora. It is therefore conceivable that the maternal vaginal microflora might
Cited by 41Related articlesView as HTMLBL DirectAll 6 versions

…, S Dalsgaard, PH Thomsen, P Thorsen – Archives of Pediatrics …, 2007 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
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DR Feikin, P Thorsen, S Zywicki, M Arpi… – American journal of …, 2001 – Elsevier
*1 Supported by the Danish Health Insurance Foundation; the Institute of Clinical Research,
University of Odense; the Foundation of Reproductive Biology, Odense University Hospital; the
National Fund for Research and Development; the Danish Ministry of Health; the Medical-
Cited by 33Related articlesBL DirectAll 5 versions

[HTML] from pnas.org…, SS Jeffrey, T Thorsen… – Proceedings of the …, 2001 – National Acad Sciences
2 (Upper) and showed a significant difference in the frequency of TP53-mutated tumors
among the subclasses (P < 0.001, two-sided). 3 A, P < 0.01), with the basal-like and
ERBB2+ subtypes associated with the shortest survival times.
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K Povlsen, P Thorsen… – European Journal of Clinical Microbiology …, 2001 – Springer
Page 1. Eur J Clin Microbiol Infect Dis (2001) 20:65–67 Q Springer-Verlag 2001 Note Relationship
of Ureaplasma urealyticum Biovars to the Presence or Absence of Bacterial Vaginosis in Pregnant
Women and to the Time of Delivery K. Povlsen, P. Thorsen, I. Lind
Cited by 28Related articlesBL DirectAll 5 versions

…, H Simhan, K Ryckman, L Jiang, P Thorsen… – American journal of …, 2006 – Elsevier
We hypothesize that genetic variations (single nucleotide polymorphisms-SNPs) in the tumor
necrosis factor-α (TNF-α), TNF receptors (TNFRI and TNFRII), interleukin-6 (IL-6) and IL-6 receptor
(IL-6R) genes predict high-risk status for spontaneous preterm birth (sPTB) in European-
Cited by 29Related articlesAll 7 versions

S Cauci, J McGregor, P Thorsen, J Grove… – American journal of …, 2005 – Elsevier
Vaginal pH ≥4.7 or pH ≥5 by itself was not associated with LBW or prematurity.
Conversely, combination of pH ≥5 and high sialidase activity demonstrated OR 17 (CI
1.8-150) for LBW; OR 31 (CI 1.8-516) for VLBW; along with OR 18 (CI 1.6-204) for preterm
Cited by 27Related articlesAll 4 versions

…, B Jacobsson, C Svaerke, P Thorsen – Archives of Pediatrics …, 2009 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
Cited by 26Related articlesAll 6 versions

SR Wann, PT Thorsen… – The Journal of Organic …, 1981 – ACS Publications
0 1981 American Chemical Society Page 2. 2580 J. Org. Chem., Vol. 46, No. 12, 1981 Wann,
Thorsen, and Kreevoy Table 11. SOC. B 1970, 1780-1783. (11) Wang, Y. Ph.D. Thesis, University
of Minnesota, 1976, p 64. (12) Yaks, K.; Stevens, JB Can. J. Chem. 1965,43,529-537.
Cited by 25Related articles

I Vogel, P Thorsen, VK Hogan… – Acta obstetricia et …, 2006 – Wiley Online Library
Objective. To examine associations of vaginal Ureaplasma urealyticum (UU) and bacterial vaginosis
(BV) with preterm delivery (PTD), small for gestational age (SGA), and low birth weight
(LBW). Material and methods. A population-based, prospective cohort study of 2,927
Cited by 24Related articlesBL DirectAll 7 versions

M Kaivola, P Thorsen… – Physical Review A, 1985 – APS
Dispersive line shapes have been observed in the population of the intermediate level of a
three-level Λ configuration in a fast beam of metastable 40 Ca * atoms. A steady-state calculation
in the weak-probe approximation is used to identify the main physical processes in the
Cited by 24Related articlesAll 5 versions

P Thorsen, DE Schendel… – Paediatric and …, 2001 – Wiley Online Library
The overall objective of the current study is to assess whether specific markers of infection (primarily
interleukin (IL) 1β, tumour necrosis factor (TNF) α, IL-6, and IL-10) obtained from maternal blood
during pregnancy, alone or in combination with other risk factors for PTD, permit
Cited by 23Related articlesBL DirectAll 5 versions

MJ Silverberg, P Thorsen, H Lindeberg… – … – Head and Neck …, 2004 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
Cited by 23Related articlesBL DirectAll 3 versions

[HTML] from nih.govS Cauci, P Thorsen, DE Schendel… – Journal of clinical …, 2003 – Am Soc Microbiol
A nested case-control study of low birth weight and preterm delivery was performed with singleton
women. Immunoglobulin A (IgA) against the Gardnerella vaginalis hemolysin (anti-Gvh IgA) and
sialidase and prolidase activities were determined in vaginal fluid at 17 weeks of
Cited by 23Related articlesBL DirectAll 13 versions

[PDF] from psu.eduMA Unger, HP Chou, T Thorsen, A Scherer… – Science, 2000 – sciencemag.org
194, 163 (1998). ↵: P. Gravesen,; J. Branebjerg,; OS Jensen. , J. Micromech. Microeng.
Seven-layer devices have been produced by this method; no obvious limitations exist to limit
the number of layers. ↵: JC Lötters,; W. Olthuis,; PH Veltink,; P. Bergveld. , J. Micromech. Microeng
Cited by 1499Related articlesBL DirectAll 25 versions

R Menon, DR Velez, P Thorsen, I Vogel… – Human …, 2006 – content.karger.com
Spontaneous preterm birth (PTB, birth before 37 weeks gestation) is a primary risk factor for neonatal
morbidity and mortality in the US. The rate of PTB is 12.2% in the United States, representing
an increase of 15% over the past decade [1, 2] . There is also a docu- mented difference
Cited by 22Related articlesBL DirectAll 5 versions

DR Velez, R Menon, P Thorsen… – Annals of Human …, 2007 – Wiley Online Library
Preterm birth (PTB) is a significant neonatal health problem that is more common in African-Americans
(AA) than in European-Americans (EA). Part of this disparity is likely to result from the differing
genetic architectures of EA and AA. To begin assessing the role of these differences,
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[HTML] from nih.gov…, SA McDonald, A Das, D Schendel, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
METHODS. For 1067 extremely low birth weight infants in the Neonatal Research Network of
the National Institute of Child Health and Human Development, levels of 25 cytokines were measured
in blood collected within 4 hours after birth and on days 3, 7, 14, and 21. Stepwise
Cited by 19Related articlesAll 5 versions

R Menon, SJ Fortunato, P Thorsen… – Journal of the Society …, 2006 – rsx.sagepub.com
Ramkumar Menon, MS, Stephen J. Fortunato, MD, Poul Thorsen, MD, PhD, and Scott
Williams, PhD KEY WORDS: Genetic association, prematurity, single-nucleotide
polymorphisms, Inultilocus analysis, MDR. 1. Twin studies supporting a genetic
Cited by 19Related articlesBL DirectAll 4 versions

HO Atladottir, MG Pedersen, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
METHODS: The study cohort consisted of all of the children born in Denmark from 1993 through
2004 (689 196 children). Outcome data consisted of both inpatient and outpatient diagnoses
reported to the Danish National Psychiatric Registry. Information on ADs in parents and
Cited by 17Related articlesAll 6 versions

AG Mikos, AJ Thorsen, LA Czerwonka, Y Bao… – Polymer, 1994 – Elsevier
A particulate-leaching method was developed to prepare highly porous biodegradable polymer
membranes. It involves the casting of polymer/salt composite membranes followed by the dissolution
of the salt. Poly(l-lactic acid) porous membranes of controlled porosity, surface/volume
Cited by 618Related articlesBL DirectAll 5 versions

U Nielsen, O Poulsen, P Thorsen… – Physical review letters, 1983 – APS
A novel technique combining the advantages of the laser-rf double-resonance scheme and
fast-beam collinear laser spectroscopy has been applied to a detailed study of the hyperfine
structure of 235 UI I. The experimental results are analyzed with use of ab initio
Cited by 15Related articlesAll 5 versions

BR Møller, FV Kristiansen, P Thorsen… – Acta obstetricia et …, 1995 – informaworld.com
Actu O hm Gwerol Scund 1995, 74: 216-219 Printed in Denmark – ull righls reserved Acta
Obstetricia et Gynecologica Scandinavica ISSN 0001-6349 BIRGER R. MDLLER, FRANK
v. KRISTIANSEN, POUL THORSEN, LARS FROST AND S0REN c. MOGENSEN
Cited by 15Related articlesBL DirectAll 5 versions

R Menon, P Thorsen, I Vogel, B Jacobsson… – American journal of …, 2008 – Elsevier
Median TNF-α concentration was associated with preterm birth when whites and blacks were
analyzed together, with cases having higher values (191.5 pg/mL) than controls (68.9
pg/mL; P < .001). There were no significant associations with sTNFR1 or sTNFR2
Cited by 15Related articlesAll 10 versions

…, DE Schendel, P Thorsen – Archives of Pediatrics and …, 2008 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
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[PDF] from uniklinikum-jena.deK Skogstrand, CK Ekelund, P Thorsen… – Journal of …, 2008 – Elsevier
The interests in monitoring inflammation by immunoassay determination of blood inflammatory
markers call for information on the stability of these markers in relation to the handling of blood
samples. The increasing use of stored biobank samples for such ventures that may have
Cited by 14Related articlesAll 7 versions

…, WD Flanders, DM Hougaard, P Thorsen – Journal of reproductive …, 2008 – Elsevier
Few studies have assessed longitudinal changes in circulating cytokine levels during normal
pregnancy. We have examined the natural history of maternal plasma cytokines from early- to
mid-pregnancy in a large, longitudinal cohort. Multiplex flow cytometry was used to
Cited by 13Related articlesAll 4 versions

…, EJ Pedersen, ES Shabanova, PA Thorsen… – Physical Review B, 1994 – APS
Department of Solid State Physics, Riso National Laboratory, DK-4000 Roskilde, Denmark E.
Jonas Pedersen, Elizaveta S. Shabanova, and Peter A. Thorsen Chemical Institute 2. 15 624
50 NMR SPECTRA OF PURE 13C DIAMOND Hd = /LO E p– [Ii *Ij-3(Ii *rij)(Ij *rij)] (1) where
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…, C Pearson, K Ortiz, N Porta, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
RESULTS. The 27 biomarkers could be classified into 1 of 3 groups: (1) biomarkers increased
in preterm birth (interleukin [IL]-2, IL-4, IL-5, IL-8, IL-10, monocyte chemoattractant protein 1, macrophage
inflammatory protein [MIP]-1 , MIP-1β, soluble IL-6 receptor , tumor necrosis factor ,
Cited by 13Related articlesAll 5 versions

R Menon, MC Camargo, P Thorsen… – American journal of …, 2008 – Elsevier
In this study, 321 amniotic fluids from cases (preterm birth 36 or fewer weeks’ gestation) and
controls (normal term delivery longer than 37 weeks’ gestation) were collected (147 cases [49
blacks and 98 whites] and 174 controls [85 blacks and 89 whites]) at the time of active
Cited by 13Related articlesAll 6 versions

I Vogel, J Grove, P Thorsen… – … of Obstetrics & …, 2005 – Wiley Online Library
*Correspondence: Dr I. Vogel, North Atlantic Neuro-epidemiology Alliances (NANEA) at Department
of Epidemiology and Social Medicine, Aarhus University, Vennelyst Boulevard 6, 8000 Aarhus
C, Denmark. Objective To evaluate whether soluble CD163 (sCD163) and C-reactive
Cited by 13Related articlesAll 3 versions

P Thorsen, I Vogel, J Olsen… – Journal of Maternal …, 2006 – informahealthcare.com
Results. At enrolment, 13.7% had BV. BV was not associated with an increased risk of spontaneous
preterm birth (crude OR 0.8 (0.5–1.5)). Nulliparity was found to affect birth weight to such a degree
that this variable was used for stratification. In nulliparous women BV was associated with
Cited by 13Related articlesBL DirectAll 5 versions

…, S Dalsgaard, PH Thomsen, P Thorsen – …, 2007 – journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. Skip Navigation Links Home > March
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…, D Hougaard, J Olsen, P Thorsen – Acta obstetricia et …, 2007 – Wiley Online Library
Background. Few studies have investigated the relationship between inflammation and spontaneous
preterm delivery (sPTD) in women before preterm labour. The authors examine whether
mid-pregnancy plasma cytokine levels are associated with sPTD, and whether
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…, LT Jensen, SA Ladefoged, P Thorsen… – Molecular …, 1998 – Wiley Online Library
Mycoplasma hominis contains a variable adherence-associated (vaa) gene. To classify variants
of the vaa genes, we examined 42 M. hominis isolates by PCR, DNA sequencing and
immunoblotting. This uncovered the existence of five gene categories. Comparison of the
Cited by 12Related articlesBL DirectAll 4 versions

DR Velez, S Fortunato, P Thorsen… – American journal of …, 2009 – Elsevier
The most significant associations were in the maternal interleukin (IL)-15 (rs10833, allele P =
2.91 × 10 −4 , genotype P = 2.00 × 10 −3 ) gene and the fetal IL-2 receptor B (IL-2RB)
(rs84460, allele P = 1.37 × 10 −4 , genotype P = 6.29 × 10 −4 ) gene. The best models for
Cited by 13Related articlesAll 7 versions

[PDF] from aace.com…, M Glavind‐Kristensen, P Thorsen… – … of Obstetrics & …, 2002 – Wiley Online Library
Setting Calculated sample size was reached over a two-year period, during which 9507 women
gave birth. Of these, 157 healthy women were eligible for the study as they were admitted with
symptoms of delivery before 34 weeks of gestation. Ninety-three women were included.
Cited by 11Related articlesAll 6 versions

[HTML] from nih.gov…, C Holzman, P Senagore, P Thorsen… – Journal of reproductive …, 2008 – Elsevier
Some spontaneous preterm deliveries (PTD) are caused by occult infections of the fetal membranes
(histologic chorioamnionitis [HCA]). High levels of infection-related markers, including some
cytokines, sampled from maternal circulation in mid-pregnancy have been linked to PTD,
Cited by 11Related articlesAll 6 versions

[HTML] from pnas.org…, D Roach, AT Woolley, T Thorsen… – Proceedings of the …, 1998 – National Acad Sciences
CrossRef. ↵: Woolley AT,; Mathies RA. (1995) Anal Chem 67:3676–3680, pmid:8644919.
Medline. ↵: Woolley AT,; Hadley D,; Landre P,; deMello AJ,; Mathies RA,; Northrup MA.
(1996) Anal Chem 68:4081–4086, pmid:8946790. Medline.
Cited by 245Related articlesBL DirectAll 11 versions

I Vogel, AR Goepfert, P Thorsen… – Journal of reproductive …, 2007 – Elsevier
This study aimed to analyze the associations between serum and cervicovaginal inflammatory
markers and recurrent spontaneous preterm birth in a cohort study of 62 pregnant women with
≥1 prior early spontaneous birth. Serum samples and cervicovaginal swabs from the
Cited by 11Related articlesAll 5 versions

P Thorsen, BR Møller… – Acta obstetricia et …, 1991 – informahealthcare.com
Semen specimens from 21 men with urethral infection with Chlamydia truchomutis were tested
for the presence of the organism before and after cryopreservation for 3 weeks of storage at –
196°C. Five specimens were chlamydia-positive before preservation and four of them
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K Mestan, Y Yu, P Thorsen, K Skogstrand… – 2009 – informahealthcare.com
Objective. In current, neonatal practice, clinical signs of intrauterine infection (IUI) are often
non-specific. From a large panel of immune biomarkers, we seek to identify cord blood markers
that are most strongly associated with the fetal inflammatory response (FIR), a specific
Cited by 11Related articlesAll 4 versions

[CITATION] Glas-Greenwalt and T. Astrup

P Thorsen – Thromb. Diath. Haemorrh, 1972
Cited by 10Related articles

…, AT Jacobsen, H Madsen, P Thorsen… – Ugeskrift for …, 2001 – ncbi.nlm.nih.gov
INTRODUCTION: Urinary incontinence is a common problem for adult women, and the need
for assessment and treatment of incontinence is expected to increase in the future. The aim of
this study was to elucidate the general practitioners’ (GPs) knowledge about and attitude
Cited by 10Related articlesAll 2 versions

…, S Lundqvist, PA Thorsen – US Patent App. 10/925,203, 2004 – Google Patents
3,2005 (54) WAVELENGTH MODULATION SPECTROSCOPY METHOD AND SYSTEM (76)
Inventors: Rikard Larking, Floda (SE); Stefan Lundqvist, Askim (SE); Per-Arne Thorsen, Ojersjo
(SE) Correspondence r- /6 fl fn n/ i P /A Lr ) 10 A 1 12 32 24 23^ -Cone ^ 22 21 19J 20 Y
Cited by 10Related articlesAll 3 versions

[HTML] from plos.orgDR Velez, SJ Fortunato, P Thorsen, SJ Lombardi… – PloS one, 2008 – dx.plos.org
Spontaneous preterm birth (<37 weeks gestation—PTB) occurs in ∼12% of pregnancies in the
United States, and is the largest contributor to neonatal morbidity and mortality. PTB is a complex
disease, potentially induced by several etiologic factors from multiple pathophysiologic
Cited by 10Related articlesCachedAll 6 versions

…, HK Poulsen, B Teisner, P Thorsen… – European Journal of …, 1993 – Elsevier
Three low-dose oral contraceptives Trinordiol ® , Gynatrol ® , and Marvelon ® , containing ethinylestradiol
(EE) in combination with triphasic levonorgestrel (LNg), monophasic levonorgestrel, and monophasic
desogestrel (DSG), respectively, were given to 65 healthy women, n = 21–22 in each
Cited by 10Related articlesAll 7 versions

P Thorsen, I Vogel, K Molsted… – Acta obstetricia et …, 2006 – Wiley Online Library
Background. No larger population-based study of bacterial vaginosis in pregnancy has previously
been available. The objective of this study was to examine risk factors for bacterial vaginosis
in pregnancy. Design. From a prospective population-based cohort of 3,596 eligible
Cited by 9Related articlesBL DirectAll 6 versions

…, K Skogstrand, P Thorsen… – Obstetrics & …, 2009 – journals.lww.com
From the 1 Perinatal Center, Department of Obstetrics and Gynecology, Institute of Clinical
Sciences, Sahlgrenska Academy, Sahlgrenska University Hospital/East, Göteborg, Sweden;
the 2 Imperial College, Institute of Reproductive and Developmental Biology, Queen
Cited by 9Related articlesAll 4 versions

…, A Madan, S Saha, D Schendel, P Thorsen… – Pediatric …, 2010 – journals.lww.com
Supported by The National Institutes of Health (General Clinical Research Center grants M01
RR30, M01 RR32, M01 RR39, M01 RR70, M01 RR80, M01 RR633, M01 RR750, M01
RR997, M01 RR6022, M01 RR7122, M01 RR8084, and M01 RR16587), the Eunice
Cited by 9Related articlesAll 5 versions

…, JL Thomsen, T Ovesen, P Thorsen – … –Head and Neck …, 2007 – oto.sagepub.com
We were able to identify 380 (61.2%) of these children in the NHR. There was no
significant difference in the severity of hearing loss between the Copenhagen children
who were found in the NHR vs those who were not (P = 0.16).
Cited by 9Related articlesAll 8 versions

R Menon, P Thorsen, I Vogel, B Jacobsson… – Placenta, 2007 – Elsevier
The objective of this study is to examine TNF-α and its soluble and membrane bound receptors
in fetal membranes derived from blacks and whites in response to in vitro infectious stimulus,
and the balance between TNF-α and the receptors. Fetal membranes collected from black
Cited by 10Related articlesAll 8 versions

…, K Skogstrand, P Thorsen… – Scandinavian …, 2007 – informahealthcare.com
IGF-I is primarily produced in the liver and mediates the anabolic effects of growth hormone
(GH). IGF-I and IGF-II are bound to six high-affinity IGF binding proteins (IGFBP-1 to
IGFBP-6) which act as carriers as well as modulators of IGF action [4]. In the circulation,
Cited by 9Related articlesBL DirectAll 7 versions

…, C Wilken‐Jensen, P Thorsen… – … of Obstetrics & …, 1994 – Wiley Online Library
How to Cite. Henriques, CU, Wilken-Jensen, C., Thorsen, P. and Møller, BR (1994), A randomised
controlled trial of prophylaxis of post-abortal infection: ceftriaxone versus placebo. BJOG: An
International Journal of Obstetrics & Gynaecology, 101: 610–614.
Cited by 9Related articlesBL DirectAll 5 versions

S Thorsen, P Glas-Greenwalt… – Thrombosis et diathesis …, 1972 – ncbi.nlm.nih.gov
1. Thromb Diath Haemorrh. 1972 Aug 31;28(1):65-74. Differences in the binding to fibrin
of urokinase and tissue plasminogen activator. Thorsen S, Glas-Greenwalt P, Astrup T.
PMID: 4672651 [PubMed – indexed for MEDLINE] MeSH Terms:
Cited by 147Related articles

…, G Røsland, F Thorsen… – … journal of cancer, 2008 – Wiley Online Library
Volume 122, Issue 4, pages 761–768, 15 February 2008. Additional Information. How to Cite.
Wang, J., Sakariassen, P. Ø., Tsinkalovsky, O., Immervoll, H., Bøe, SO, Svendsen, A., Prestegarden,
L., Røsland, G., Thorsen, F., Stuhr, L., Molven, A., Bjerkvig, R. and Enger, P. Ø.
Cited by 139Related articlesBL DirectAll 4 versions

[HTML] from biomedcentral.com…, C Wiuf, O Mors, M Didriksen, P Thorsen… – BMC …, 2009 – biomedcentral.com
Identification of disease susceptible genes requires access to DNA from numerous well-characterised
subjects. Archived residual dried blood spot samples from national newborn screening programs
may provide DNA from entire populations and medical registries the corresponding
Cited by 8Related articlesCachedAll 9 versions

…, T Lundström, SD Berkowitz, P Nyström… – JAMA: the journal of …, 2005 – Am Med Assoc
15-19 Kaplan-Meier estimates of the cumulative risk and the corresponding variance according
to the Greenwood formula were used when calculating the CI and the corresponding P values.
All reported P values are 2-sided; P<.05 was considered statistically significant.
Cited by 130Related articlesAll 10 versions

…, PL Thorsen – The High School Journal, 1985 – JSTOR
Both my wife Sandie and I (SPM) teach at a Christian liberal arts college. We both are ex- cited
about and revel in this vocational choice. However, it has placed us where we regularly deal
with the interaction between dogmatism on the one hand and developing a thoughtful
Cited by 8Related articles

[CITATION] Vanishing embryo syndrome

…, M Vaeth, E Ernst, L Nielsen, P Thorsen – IVF/ICSI. Hum Reprod, 2005
Cited by 8Related articles

…, I Vogel, K Skogstrand, P Thorsen… – Journal of reproductive …, 2008 – Elsevier
Pregnant women admitted with symptoms of threatening PTD and delivering before 34 weeks
of gestation had significantly lower levels of IL-18 compared to women delivering at or after 34
weeks of gestation (medians: 14.5 versus 26.6 pg/ml; p = 0.035). IL-12 levels were not
Cited by 8Related articlesAll 6 versions

PA Thorsen… – Materials Science and Engineering: A, 1999 – Elsevier
A more detailed discussion of the grain boundary structure effects that must be considered in
a modified theory has been given by Bilde-Sørensen and Thorsen [27]. Acknowledgements.
References. [1] OA Ruano, J. Wadsworth and OD Sherby, Acta Metall. 36 (1988), p. 1117.
Cited by 8Related articlesAll 3 versions

SL Hansen, P Thorsen, K Dybdal… – Photonics …, 1993 – ieeexplore.ieee.org
Abstract-The gain tilt responsible for second-order distortion generated by EDFA’s in AM
TV-systems is shown to be funda- mentally different from previous belief. The relevant gain-tilt
should be measured under locked-inversion conditions. It in- creases with signal
Cited by 8Related articlesBL DirectAll 4 versions

…, R Menon, DR Velez, P Thorsen… – American journal of …, 2008 – Elsevier
In white patients, multilocus interactions in maternal DNA between single nucleotide polymorphisms
at −7227 (interleukin-6), 22,215 (interleuki-6 receptor) and −3448 (tumor necrosis
factor-alpha) was predictive of approximately 59.1% (P < .02; odds ratio, 2.3 [95%
Cited by 8Related articlesAll 8 versions

[HTML] from rbej.com…, SM Williams, SJ Fortunato, P Thorsen – Reproductive Biology …, 2009 – rbej.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution
License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use,
distribution, and reproduction in any medium, provided the original work is properly cited.
Cited by 8Related articlesCachedAll 10 versions

HO Atladóttir, P Thorsen, L Østergaard… – Journal of autism and …, 2010 – Springer
Abstract Exposure to prenatal infection has been sug- gested to cause deficiencies in fetal
neurodevelopment. In this study we included all children born in Denmark from 1980, through
2005. Diagnoses of autism spectrum disorders (ASDs) and maternal infection were
Cited by 9Related articlesAll 6 versions

…, BH Bech, J Olsen, P Thorsen – Paediatric and …, 2008 – Wiley Online Library
In a previous study, we found that infants transferred to a neonatal ward after delivery had an
almost twofold increased risk of being diagnosed with infantile autism later in childhood in spite
of extensive controlling of obstetric risk factors. We therefore decided to investigate other
Cited by 8Related articlesAll 3 versions

[CITATION] Untitled

MA Unger, HP Chou, TA Thorsen, A Scherer… – US Patent 6,408,878, 2002
Cited by 118Related articles

P Kuban, A Engström, JC Olsson, G Thorsén… – Analytica chimica …, 1997 – Elsevier
17124 New interface for coupling nowinjection and capillary electrophoresis Petr Kuban, Anders
Engstrom, Joanna C. Olsson, Gunnar Thorsen, Robert Tryzell 00032670 97 S17.00 Copyright @
1997 Eisevier Science BV AI) rights reserved ‘ S00032670(96)00339X 118 P. A’uan
Cited by 111Related articlesBL DirectAll 4 versions

…, NP Bent, C Sværke, P Thorsen – Obstetrics & …, 2008 – journals.lww.com
From the 1 Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen,
Denmark; 2 NANEA at Department of Epidemiology, Institute of Public Health, University of
Aarhus, Aarhus, Denmark; the 3 National Center on Birth Defects and Developmental
Cited by 7Related articlesAll 3 versions

S Lundqvist… – US Patent 7,193,718, 2007 – Google Patents
20, 2007 (54) WAVELENGTH MODULATION SPECTROSCOPY METHOD AND SYSTEM (75)
Inventors: Stefan Lundqvist, Askim (SE); Per-Arne Thorsen, Ojersjo (SE) (73) Assignee of origin
in the 5 non-linearity of the laser IP characteristics (I is the injection current and P is the
Cited by 7Related articlesAll 2 versions

NP Thorsen… – US Patent 5,033,713, 1991 – Google Patents
United States Patent Thorsen et al. [19] [ii] Patent Number: [45] Date of Patent: 5,033,713 Jul.
23, 1991 [54] TEMPERATURE-SENSITIVE ACTUATING APPARATUS FOR A SERVO-APPARATUS
[75] Inventors: Niels P. Thorsen, Sydals; Bjarke Hallenslev, Nordborg, both of Denmark
Cited by 7Related articlesAll 2 versions

[HTML] from oxfordjournals.org…, M Væth, E Ernst, L Nielsen, P Thorsen – Human …, 2005 – ESHRE
BACKGROUND: In a Danish population-based cohort study assessing the risk of cerebral palsy
in children born after IVF, we made some interesting observations regarding ‘vanishing
co-embryos’. METHODS and RESULTS: All live-born children born in Denmark from 1
Cited by 7Related articlesBL DirectAll 6 versions

[CITATION] Racial Disparity in Amniotic Fluid Tumor Necrosis Factor-α and soluble TNF Receptor Concentrations in Spontaneous Pretrem Birth: Evidence for Incresed …

R Menon, P Thorsen, I Vogel, B Jacobsson… – American Journal of …, 2008 – unknown
Cited by 7Related articles

[HTML] from nih.gov…, DJ Dudley, DE Schendel, P Thorsen – American journal of …, 2008 – Elsevier
Presented at the 14th Annual Meeting of the Psychoneuroimmunology Research Society,
Arcachon, France, May 30 through June 2, 2007. 6 National Center on Birth Defects and Developmental
Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.
Cited by 7Related articlesAll 7 versions

[PDF] from clinchem.org…, B Norgaard-Pedersen, P Thorsen… – Clinical …, 2007 – Am Assoc Clin Chem
Programs to screen newborns for congenital disorders are based on analysis of dried blood
spot samples (DBSS), which have proven to be robust and convenient for collection,
transport, and storage. Because blood samples are collected with no selection, and
Cited by 7Related articlesBL DirectAll 4 versions

[PDF] from csic.es…, F Saborido-Rey, PR Witthames, A Thorsen… – 2003 – digital.csic.es
PR Witthames Centre for Environmennt, Fisheries and Aquaculture Science, Lowestoft
Laboratory Lowestoft, Suffolk NR33, 0HT, England A. Thorsen Institute of Marine Research,
PO Box 1870 Nordnes, Nordnesgaten 50, N-5817 Bergen, Norway
Cited by 72Related articlesView as HTMLAll 10 versions

[PDF] from sgmjournals.orgLT Jensen, P Thorsen, B MOsller… – Journal of medical …, 1998 – Soc General Microbiol
J. Med. Microbiol. – Vol. 47 (1998), 659-666 ( > 1998 The Pathological Society of Great Britain
and Ireland MOLECULAR I DENTI FICATION AND EPI DEM IOLOGY LlSE T. JENSEN,
P. THORSEN*, B. M0LLER*, S. BIRKELUND and G. CHRISTIANSEN
Cited by 6Related articlesBL DirectAll 4 versions

[PDF] from mit.eduJP Urbanski, T Thorsen, JA Levitan… – Applied physics letters, 2006 – link.aip.org
Fast ac electro-osmotic micropumps with nonplanar electrodes. [Applied Physics Letters 89,
143508 (2006)]. John Paul Urbanski, Todd Thorsen, Jeremy A. Levitan, Martin Z. Bazant. Abstract.
Author to whom correspondence should be addressed; electronic mail: thorsen@mit.edu
Cited by 72Related articlesBL DirectAll 9 versions

MV Hollegaard, J Grove, P Thorsen… – Genetic Testing and …, 2009 – liebertonline.com
Aims: The aim of this study was to investigate if dried blood spot (DBS) samples stored in the
Danish Neonatal Screening Biobank (DNSB) and the Danish National Birth Cohort (DNBC) repository
are useful for Illumina single- nucleotide polymorphism (SNP) genotyping. Genomic DNA (
Cited by 6Related articlesAll 2 versions

[PDF] from au.dkI Vogel, P Thorsen, HH Hundborg… – European Journal of …, 2006 – Elsevier
In the women with a subsequent preterm delivery the relaxin level decreased by 0.9% per week
as compared to 1.9% per week (t-test, p = 0.004) in the women with term deliveries. From the
cohort the course of S-relaxin during pregnancy in both preterm and term deliveries were
Cited by 6Related articlesAll 7 versions

[HTML] from fasebj.org…, M Hjelstuen, PERȖ ENGER, F Thorsen… – The FASEB Journal, 2002 – FASEB
MARTHA CHEKENYA * , MARI HJELSTUEN ‡ , PER ØYVIND ENGER * , FRITS THORSEN * ,
ANNE L. JACOB * , BEATRICE PROBST * , OLAV HARALDSETH § , GEOFFREY PILKINGTON
II , ARTHUR BUTT ¶ , JOEL M LEVINE ** and WT (P<0.001) and control cells (P<0.05).
Cited by 64Related articlesBL DirectAll 3 versions

…, SJ Hamilton-Dutoit, S Thorsen… – European journal of …, 1991 – ncbi.nlm.nih.gov
and prognostic features. Pedersen C, Gerstoft J, Lundgren JD, Skinhøj P, Bøttzauw
J, Geisler C, Hamilton-Dutoit SJ, Thorsen S, Lisse I, Ralfkiaer E, et al. Department
of Infectious Diseases, Hvidovre Hospital, Denmark. All 51
Cited by 61Related articlesAll 2 versions

H Alfredson, D Bjur, K Thorsen… – Journal of …, 2002 – Wiley Online Library
In this investigation the microdialysis technique was used to study the concentrations of lactate
in Achilles tendons with painful chronic tendinosis and in normal pain-free tendons. In four patients
(mean age 40.7 years) with a painful thickening localized at the 2-6 cni level in the
Cited by 63Related articlesAll 6 versions

P Nordström, K Thorsen, G Nordström, E Bergström… – Bone, 1995 – Elsevier
This study was conducted to evaluate the association between muscle strength of the thigh, different
body constitutional parameters, and bone mineral density (BMD) in adolescents. The subjects
were 26 healthy adolescent boys, age 15.9 ± 0.3 years, not training for more than 3 h per
Cited by 56Related articlesBL DirectAll 8 versions

[PDF] from safeminds.org…, D Schendel, J Wohlfahrt, P Thorsen… – New England Journal …, 2002 – nejm.org
We conducted a retrospective cohort study of all children born in Denmark from January 1991
through December 1998. The cohort was selected on the basis of data from the Danish Civil
Registration System, which assigns a unique identification number to every live-born
Cited by 383Related articlesBL DirectAll 26 versions

[HTML] from oxfordjournals.org…, E Agerbo, D Schendel, P Thorsen… – American Journal of …, 2005 – Oxford Univ Press
Research suggests that heredity and early fetal development play a causal role in autism. This
case-control study explored the association between perinatal factors, parental psychiatric
history, socioeconomic status, and risk of autism. The study was nested within a cohort of
Cited by 182Related articlesAll 15 versions

[PDF] from pkids.org…, MB Lauritsen, CB Pedersen, P Thorsen… – Pediatrics, 2003 – Am Acad Pediatrics
Objective. It has been suggested that thimerosal, a mercury-containing preservative in
vaccines, is a risk factor for the development of autism. We examined whether discontinuing
the use of thimerosal-containing vaccines in Denmark led to a decrease in the incidence
Cited by 148Related articlesBL DirectAll 33 versions

MJ Silverberg, P Thorsen, H Lindeberg… – Obstetrics & …, 2003 – journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. Skip Navigation Links Home > April
Cited by 125Related articlesAll 8 versions

P Thorsen, IP Jensen, B Jeune, N Ebbesen… – American journal of …, 1998 – Elsevier
Attempts to identify infections in the lower genital tract in women as one of the causes of pathologic
pregnancy outcome have been made throughout several decades. Recently, efforts have been
concentrated on the condition of BV as described by Amsel et al. 5 The diagnostic criteria
Cited by 97Related articlesBL DirectAll 4 versions

[HTML] from endojournals.orgK Erickson, P Thorsen, G Chrousos… – Journal of Clinical …, 2001 – Endocrine Soc
Increased CRH secretion by the placenta of pregnant women has been associated with preterm
birth. Certain indices of risk, both medical and psychosocial in nature, have been linked to preterm
delivery. Levels of total, bound, and free CRH, CRH-binding protein (CRH-BP), and
Cited by 80Related articlesBL DirectAll 5 versions

[HTML] from clinchem.orgK Skogstrand, P Thorsen… – Clinical …, 2005 – Am Assoc Clin Chem
Background: Inflammatory reactions and other events in early life may be part of the etiology
of late-onset diseases, including cerebral palsy, autism, and type 1 diabetes. Most neonatal screening
programs for congenital disorders are based on analysis of dried blood spot samples
Cited by 75Related articlesBL DirectAll 5 versions

C Floridon, CH Jensen, P Thorsen… – …, 2000 – Wiley Online Library
Abstract Fetal antigen 1 (FA1) is a circulating EGF multidomain glycoprotein. FA1 and its
membrane-associated precursor is defined by the mRNAs referred to as delta-like (dlk), preadipocyte
factor 1 (pref-1) or zona glomerulosa-specific factor (ZOG). Using a polyclonal antibody
Cited by 64Related articlesBL DirectAll 4 versions

I Vogel, P Thorsen, A Curry… – Acta obstetricia et …, 2005 – Wiley Online Library
Among symptomatic women, the likelihood ratio (LR+) for the prediction of PTD was found to
be greater than 10 using amniotic fluid (AF) interleukin-6 (IL-6), AF Ureaplasma urealyticum,
as well as a multi-marker consisting of cervical IL-6, cervical IL-8, and cervical length
Cited by 55Related articlesAll 7 versions

IP Jensen, P Thorsen, B Jeune… – … of Obstetrics & …, 2000 – Wiley Online Library
Objectives To estimate the incidence of human parvovirus B19 among pregnant women before
and during an epidemic, to elucidate possible sociodemographic and medical risk factors during
pregnancy and to estimate the association between parvovirus B19 infection and
Cited by 53Related articlesBL DirectAll 4 versions

…, KM Madsen, J Wohlfahrt, P Thorsen… – JAMA: the journal of …, 2004 – Am Med Assoc
Author Affiliations: The Danish Epidemiology Science Centre, Department of Epidemiology and
Social Medicine, Aarhus University, Aarhus (Drs Vestergaard, Madsen, and Olsen), The Danish
Epidemiology Science Centre, Department of Epidemiology Research, Statens Serum
Cited by 51Related articlesBL DirectAll 6 versions

IP Jensen, P Thorsen… – Lancet, 1997 – ncbi.nlm.nih.gov
1. Lancet. 1997 Feb 1;349(9048):329-30. Sensitivity of ligase chain reaction assay of urine from
pregnant women for Chlamydia trachomatis. Jensen IP, Thorsen P, Møller BR. Comment in: Lancet.
1997 Apr 5;349(9057):1024-5. Lancet. 1998 Jan 31;351(9099):341-2. Lancet.
Cited by 48Related articlesBL DirectAll 6 versions

GB Hvilsom, P Thorsen, B Jeune… – Acta obstetricia et …, 2002 – Wiley Online Library
Methods. The present study is a prospective nested case-control study including 84
singleton, preterm deliveries (cases) and 400 singleton, term deliveries (controls), based at the
Odense University Hospital, Denmark. These cases were identified from a cohort of 2846
Cited by 43Related articlesBL DirectAll 8 versions

[HTML] from shouxi.net…, M Vaeth, E Ernst, LF Nielsen, P Thorsen – Pediatrics, 2006 – Am Acad Pediatrics
METHODS. A population-based, cohort study, including all live-born singletons and twins born
in Denmark between January 1, 1995, and December 31, 2000, was performed. Children conceived
with in vitro fertilization (9255 children) were identified through the In Vitro Fertilization
Cited by 42Related articlesBL DirectAll 8 versions

…, A Schuchat, P Thorsen – Mental retardation and …, 2002 – Wiley Online Library
Cerebral palsy is the most common neuromotor developmental dis- ability of childhood, affecting
as many as 8,000 to 12,000 children born in the US each year (corresponding to a prevalence
rate of between 2 and 3 per 1000 children). Recent improvements in neonatal care have
Cited by 42Related articlesBL DirectAll 3 versions

[PDF] from dbac.dkCS Benn, P Thorsen, JS Jensen, BB Kjoer… – Journal of allergy and …, 2002 – dbac.dk
Background: Infants with wheezing and allergic diseases have a microflora that differs from that
of healthy infants. The fetus acquires microorganisms during birth when exposed to the maternal
vaginal microflora. It is therefore conceivable that the maternal vaginal microflora might
Cited by 41Related articlesView as HTMLBL DirectAll 6 versions

…, S Dalsgaard, PH Thomsen, P Thorsen – Archives of Pediatrics …, 2007 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
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DR Feikin, P Thorsen, S Zywicki, M Arpi… – American journal of …, 2001 – Elsevier
*1 Supported by the Danish Health Insurance Foundation; the Institute of Clinical Research,
University of Odense; the Foundation of Reproductive Biology, Odense University Hospital; the
National Fund for Research and Development; the Danish Ministry of Health; the Medical-
Cited by 33Related articlesBL DirectAll 5 versions

…, H Simhan, K Ryckman, L Jiang, P Thorsen… – American journal of …, 2006 – Elsevier
We hypothesize that genetic variations (single nucleotide polymorphisms-SNPs) in the tumor
necrosis factor-α (TNF-α), TNF receptors (TNFRI and TNFRII), interleukin-6 (IL-6) and IL-6 receptor
(IL-6R) genes predict high-risk status for spontaneous preterm birth (sPTB) in European-
Cited by 29Related articlesAll 7 versions

S Cauci, J McGregor, P Thorsen, J Grove… – American journal of …, 2005 – Elsevier
Vaginal pH ≥4.7 or pH ≥5 by itself was not associated with LBW or prematurity.
Conversely, combination of pH ≥5 and high sialidase activity demonstrated OR 17 (CI
1.8-150) for LBW; OR 31 (CI 1.8-516) for VLBW; along with OR 18 (CI 1.6-204) for preterm
Cited by 27Related articlesAll 4 versions

…, B Jacobsson, C Svaerke, P Thorsen – Archives of Pediatrics …, 2009 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
Cited by 26Related articlesAll 6 versions

I Vogel, P Thorsen, VK Hogan… – Acta obstetricia et …, 2006 – Wiley Online Library
Objective. To examine associations of vaginal Ureaplasma urealyticum (UU) and bacterial vaginosis
(BV) with preterm delivery (PTD), small for gestational age (SGA), and low birth weight
(LBW). Material and methods. A population-based, prospective cohort study of 2,927
Cited by 24Related articlesBL DirectAll 7 versions

[HTML] from nih.govS Cauci, P Thorsen, DE Schendel… – Journal of clinical …, 2003 – Am Soc Microbiol
A nested case-control study of low birth weight and preterm delivery was performed with singleton
women. Immunoglobulin A (IgA) against the Gardnerella vaginalis hemolysin (anti-Gvh IgA) and
sialidase and prolidase activities were determined in vaginal fluid at 17 weeks of
Cited by 23Related articlesBL DirectAll 13 versions

MJ Silverberg, P Thorsen, H Lindeberg… – … – Head and Neck …, 2004 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
Cited by 23Related articlesBL DirectAll 3 versions

P Thorsen, DE Schendel… – Paediatric and …, 2001 – Wiley Online Library
The overall objective of the current study is to assess whether specific markers of infection (primarily
interleukin (IL) 1β, tumour necrosis factor (TNF) α, IL-6, and IL-10) obtained from maternal blood
during pregnancy, alone or in combination with other risk factors for PTD, permit
Cited by 23Related articlesBL DirectAll 5 versions

[HTML] from nih.gov…, SA McDonald, A Das, D Schendel, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
METHODS. For 1067 extremely low birth weight infants in the Neonatal Research Network of
the National Institute of Child Health and Human Development, levels of 25 cytokines were measured
in blood collected within 4 hours after birth and on days 3, 7, 14, and 21. Stepwise
Cited by 19Related articlesAll 5 versions

R Menon, SJ Fortunato, P Thorsen… – Journal of the Society …, 2006 – rsx.sagepub.com
Ramkumar Menon, MS, Stephen J. Fortunato, MD, Poul Thorsen, MD, PhD, and Scott
Williams, PhD KEY WORDS: Genetic association, prematurity, single-nucleotide
polymorphisms, Inultilocus analysis, MDR. 1. Twin studies supporting a genetic
Cited by 19Related articlesBL DirectAll 4 versions

HO Atladottir, MG Pedersen, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
METHODS: The study cohort consisted of all of the children born in Denmark from 1993 through
2004 (689 196 children). Outcome data consisted of both inpatient and outpatient diagnoses
reported to the Danish National Psychiatric Registry. Information on ADs in parents and
Cited by 17Related articlesAll 6 versions

BR Møller, FV Kristiansen, P Thorsen… – Acta obstetricia et …, 1995 – informaworld.com
Actu O hm Gwerol Scund 1995, 74: 216-219 Printed in Denmark – ull righls reserved Acta
Obstetricia et Gynecologica Scandinavica ISSN 0001-6349 BIRGER R. MDLLER, FRANK
v. KRISTIANSEN, POUL THORSEN, LARS FROST AND S0REN c. MOGENSEN
Cited by 15Related articlesBL DirectAll 5 versions

…, DE Schendel, P Thorsen – Archives of Pediatrics and …, 2008 – Am Med Assoc
You are seeing this message because your Web browser does not support basic Web
standards. Find out more about why this message is appearing and what you can do to make
your experience on this site better. Add to CiteULike Add to Connotea Add to
Cited by 14Related articlesAll 4 versions

[PDF] from uniklinikum-jena.deK Skogstrand, CK Ekelund, P Thorsen… – Journal of …, 2008 – Elsevier
The interests in monitoring inflammation by immunoassay determination of blood inflammatory
markers call for information on the stability of these markers in relation to the handling of blood
samples. The increasing use of stored biobank samples for such ventures that may have
Cited by 14Related articlesAll 7 versions

R Menon, P Thorsen, I Vogel, B Jacobsson… – American journal of …, 2008 – Elsevier
Median TNF-α concentration was associated with preterm birth when whites and blacks were
analyzed together, with cases having higher values (191.5 pg/mL) than controls (68.9
pg/mL; P < .001). There were no significant associations with sTNFR1 or sTNFR2
Cited by 15Related articlesAll 10 versions

P Thorsen, I Vogel, J Olsen… – Journal of Maternal …, 2006 – informahealthcare.com
Results. At enrolment, 13.7% had BV. BV was not associated with an increased risk of spontaneous
preterm birth (crude OR 0.8 (0.5–1.5)). Nulliparity was found to affect birth weight to such a degree
that this variable was used for stratification. In nulliparous women BV was associated with
Cited by 13Related articlesBL DirectAll 5 versions

I Vogel, J Grove, P Thorsen… – … of Obstetrics & …, 2005 – Wiley Online Library
*Correspondence: Dr I. Vogel, North Atlantic Neuro-epidemiology Alliances (NANEA) at Department
of Epidemiology and Social Medicine, Aarhus University, Vennelyst Boulevard 6, 8000 Aarhus
C, Denmark. Objective To evaluate whether soluble CD163 (sCD163) and C-reactive
Cited by 13Related articlesAll 3 versions

R Menon, MC Camargo, P Thorsen… – American journal of …, 2008 – Elsevier
In this study, 321 amniotic fluids from cases (preterm birth 36 or fewer weeks’ gestation) and
controls (normal term delivery longer than 37 weeks’ gestation) were collected (147 cases [49
blacks and 98 whites] and 174 controls [85 blacks and 89 whites]) at the time of active
Cited by 13Related articlesAll 6 versions

…, C Pearson, K Ortiz, N Porta, P Thorsen… – Pediatrics, 2009 – Am Acad Pediatrics
RESULTS. The 27 biomarkers could be classified into 1 of 3 groups: (1) biomarkers increased
in preterm birth (interleukin [IL]-2, IL-4, IL-5, IL-8, IL-10, monocyte chemoattractant protein 1, macrophage
inflammatory protein [MIP]-1 , MIP-1β, soluble IL-6 receptor , tumor necrosis factor ,
Cited by 13Related articlesAll 5 versions

…, D Hougaard, J Olsen, P Thorsen – Acta obstetricia et …, 2007 – Wiley Online Library
Background. Few studies have investigated the relationship between inflammation and spontaneous
preterm delivery (sPTD) in women before preterm labour. The authors examine whether
mid-pregnancy plasma cytokine levels are associated with sPTD, and whether
Cited by 12Related articlesBL DirectAll 8 versions

…, S Dalsgaard, PH Thomsen, P Thorsen – …, 2007 – journals.lww.com
Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining
your privacy and will not share your personal information without your express consent. For more
information, please refer to our Privacy Policy. Skip Navigation Links Home > March
Cited by 12Related articlesBL DirectAll 3 versions

…, LT Jensen, SA Ladefoged, P Thorsen… – Molecular …, 1998 – Wiley Online Library
Mycoplasma hominis contains a variable adherence-associated (vaa) gene. To classify variants
of the vaa genes, we examined 42 M. hominis isolates by PCR, DNA sequencing and
immunoblotting. This uncovered the existence of five gene categories. Comparison of the
Cited by 12Related articlesBL DirectAll 4 versions

DR Velez, S Fortunato, P Thorsen… – American journal of …, 2009 – Elsevier
The most significant associations were in the maternal interleukin (IL)-15 (rs10833, allele P =
2.91 × 10 −4 , genotype P = 2.00 × 10 −3 ) gene and the fetal IL-2 receptor B (IL-2RB)
(rs84460, allele P = 1.37 × 10 −4 , genotype P = 6.29 × 10 −4 ) gene. The best models for
Cited by 13Related articlesAll 7 versions

P Thorsen, BR Møller… – Acta obstetricia et …, 1991 – informahealthcare.com
Semen specimens from 21 men with urethral infection with Chlamydia truchomutis were tested
for the presence of the organism before and after cryopreservation for 3 weeks of storage at –
196°C. Five specimens were chlamydia-positive before preservation and four of them
Cited by 11Related articlesAll 5 versions

I Vogel, AR Goepfert, P Thorsen… – Journal of reproductive …, 2007 – Elsevier
This study aimed to analyze the associations between serum and cervicovaginal inflammatory
markers and recurrent spontaneous preterm birth in a cohort study of 62 pregnant women with
≥1 prior early spontaneous birth. Serum samples and cervicovaginal swabs from the
Cited by 11Related articlesAll 5 versions

[HTML] from nih.gov…, C Holzman, P Senagore, P Thorsen… – Journal of reproductive …, 2008 – Elsevier
Some spontaneous preterm deliveries (PTD) are caused by occult infections of the fetal membranes
(histologic chorioamnionitis [HCA]). High levels of infection-related markers, including some
cytokines, sampled from maternal circulation in mid-pregnancy have been linked to PTD,
Cited by 11Related articlesAll 6 versions

[PDF] from aace.com…, M Glavind‐Kristensen, P Thorsen… – … of Obstetrics & …, 2002 – Wiley Online Library
Setting Calculated sample size was reached over a two-year period, during which 9507 women
gave birth. Of these, 157 healthy women were eligible for the study as they were admitted with
symptoms of delivery before 34 weeks of gestation. Ninety-three women were included.
Cited by 11Related articlesAll 6 versions

K Mestan, Y Yu, P Thorsen, K Skogstrand… – 2009 – informahealthcare.com
Objective. In current, neonatal practice, clinical signs of intrauterine infection (IUI) are often
non-specific. From a large panel of immune biomarkers, we seek to identify cord blood markers
that are most strongly associated with the fetal inflammatory response (FIR), a specific
Cited by 11Related articlesAll 4 versions

…, HK Poulsen, B Teisner, P Thorsen… – European Journal of …, 1993 – Elsevier
Three low-dose oral contraceptives Trinordiol ® , Gynatrol ® , and Marvelon ® , containing ethinylestradiol
(EE) in combination with triphasic levonorgestrel (LNg), monophasic levonorgestrel, and monophasic
desogestrel (DSG), respectively, were given to 65 healthy women, n = 21–22 in each
Cited by 10Related articlesAll 7 versions

[HTML] from plos.orgDR Velez, SJ Fortunato, P Thorsen, SJ Lombardi… – PloS one, 2008 – dx.plos.org
Spontaneous preterm birth (<37 weeks gestation—PTB) occurs in ∼12% of pregnancies in the
United States, and is the largest contributor to neonatal morbidity and mortality. PTB is a complex
disease, potentially induced by several etiologic factors from multiple pathophysiologic
Cited by 10Related articlesCachedAll 6 versions

…, C Wilken‐Jensen, P Thorsen… – … of Obstetrics & …, 1994 – Wiley Online Library
A randomised controlled trial of prophylaxis of post-abortal infection: ceftriaxone versus
placebo. Carsten Ulrik Henriques Registrar 1 ,; Charlotte Wilken-Jensen Registrar 1 ,;
Poul Thorsen Registrar 1 ,; Birger R. Møller Associate Professor 2,*.
Cited by 9Related articlesBL DirectAll 5 versions

P Thorsen, I Vogel, K Molsted… – Acta obstetricia et …, 2006 – Wiley Online Library
Background. No larger population-based study of bacterial vaginosis in pregnancy has previously
been available. The objective of this study was to examine risk factors for bacterial vaginosis
in pregnancy. Design. From a prospective population-based cohort of 3,596 eligible
Cited by 9Related articlesBL DirectAll 6 versions

…, A Madan, S Saha, D Schendel, P Thorsen… – Pediatric …, 2010 – journals.lww.com
Supported by The National Institutes of Health (General Clinical Research Center grants M01
RR30, M01 RR32, M01 RR39, M01 RR70, M01 RR80, M01 RR633, M01 RR750, M01
RR997, M01 RR6022, M01 RR7122, M01 RR8084, and M01 RR16587), the Eunice
Cited by 9Related articlesAll 5 versions

…, JL Thomsen, T Ovesen, P Thorsen – … –Head and Neck …, 2007 – oto.sagepub.com
Cited by 9Related articlesAll 8 versions

…, K Skogstrand, P Thorsen… – Obstetrics & …, 2009 – journals.lww.com
From the 1 Perinatal Center, Department of Obstetrics and Gynecology, Institute of Clinical
Sciences, Sahlgrenska Academy, Sahlgrenska University Hospital/East, Göteborg, Sweden;
the 2 Imperial College, Institute of Reproductive and Developmental Biology, Queen
Cited by 9Related articlesAll 4 versions

R Menon, P Thorsen, I Vogel, B Jacobsson… – Placenta, 2007 – Elsevier
The objective of this study is to examine TNF-α and its soluble and membrane bound receptors
in fetal membranes derived from blacks and whites in response to in vitro infectious stimulus,
and the balance between TNF-α and the receptors. Fetal membranes collected from black
Cited by 10Related articlesAll 8 versions

…, K Skogstrand, P Thorsen… – Scandinavian …, 2007 – informahealthcare.com
IGF-I is primarily produced in the liver and mediates the anabolic effects of growth hormone
(GH). IGF-I and IGF-II are bound to six high-affinity IGF binding proteins (IGFBP-1 to
IGFBP-6) which act as carriers as well as modulators of IGF action [4]. In the circulation,
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…, BH Bech, J Olsen, P Thorsen – Paediatric and …, 2008 – Wiley Online Library
In a previous study, we found that infants transferred to a neonatal ward after delivery had an
almost twofold increased risk of being diagnosed with infantile autism later in childhood in spite
of extensive controlling of obstetric risk factors. We therefore decided to investigate other
Cited by 8Related articlesAll 3 versions

[HTML] from biomedcentral.com…, C Wiuf, O Mors, M Didriksen, P Thorsen… – BMC …, 2009 – biomedcentral.com
Identification of disease susceptible genes requires access to DNA from numerous well-characterised
subjects. Archived residual dried blood spot samples from national newborn screening programs
may provide DNA from entire populations and medical registries the corresponding
Cited by 8Related articlesCachedAll 9 versions

…, R Menon, DR Velez, P Thorsen… – American journal of …, 2008 – Elsevier
In white patients, multilocus interactions in maternal DNA between single nucleotide polymorphisms
at −7227 (interleukin-6), 22,215 (interleuki-6 receptor) and −3448 (tumor necrosis
factor-alpha) was predictive of approximately 59.1% (P < .02; odds ratio, 2.3 [95%
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[HTML] from rbej.com…, SM Williams, SJ Fortunato, P Thorsen – Reproductive Biology …, 2009 – rbej.com
This is an Open Access article distributed under the terms of the Creative Commons Attribution
License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use,
distribution, and reproduction in any medium, provided the original work is properly cited.
Cited by 8Related articlesCachedAll 10 versions

HO Atladóttir, P Thorsen, L Østergaard… – Journal of autism and …, 2010 – Springer
Abstract Exposure to prenatal infection has been sug- gested to cause deficiencies in fetal
neurodevelopment. In this study we included all children born in Denmark from 1980, through
2005. Diagnoses of autism spectrum disorders (ASDs) and maternal infection were
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[HTML] from oxfordjournals.org…, M Væth, E Ernst, L Nielsen, P Thorsen – Human …, 2005 – ESHRE
BACKGROUND: In a Danish population-based cohort study assessing the risk of cerebral palsy
in children born after IVF, we made some interesting observations regarding ‘vanishing
co-embryos’. METHODS and RESULTS: All live-born children born in Denmark from 1
Cited by 7Related articlesBL DirectAll 6 versions

[PDF] from clinchem.org…, B Norgaard-Pedersen, P Thorsen… – Clinical …, 2007 – Am Assoc Clin Chem
Programs to screen newborns for congenital disorders are based on analysis of dried blood
spot samples (DBSS), which have proven to be robust and convenient for collection,
transport, and storage. Because blood samples are collected with no selection, and
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[HTML] from nih.gov…, DJ Dudley, DE Schendel, P Thorsen – American journal of …, 2008 – Elsevier
Presented at the 14th Annual Meeting of the Psychoneuroimmunology Research Society,
Arcachon, France, May 30 through June 2, 2007. 6 National Center on Birth Defects and Developmental
Disabilities, Centers for Disease Control and Prevention, Atlanta, GA.
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…, NP Bent, C Sværke, P Thorsen – Obstetrics & …, 2008 – journals.lww.com
From the 1 Department of Clinical Biochemistry, Statens Serum Institut, Copenhagen,
Denmark; 2 NANEA at Department of Epidemiology, Institute of Public Health, University of
Aarhus, Aarhus, Denmark; the 3 National Center on Birth Defects and Developmental
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[CITATION] Racial Disparity in Amniotic Fluid Tumor Necrosis Factor-α and soluble TNF Receptor Concentrations in Spontaneous Pretrem Birth: Evidence for Incresed …

R Menon, P Thorsen, I Vogel, B Jacobsson… – American Journal of …, 2008 – unknown
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[PDF] from au.dkI Vogel, P Thorsen, HH Hundborg… – European Journal of …, 2006 – Elsevier
In the women with a subsequent preterm delivery the relaxin level decreased by 0.9% per week
as compared to 1.9% per week (t-test, p = 0.004) in the women with term deliveries. From the
cohort the course of S-relaxin during pregnancy in both preterm and term deliveries were
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MV Hollegaard, J Grove, P Thorsen… – Genetic Testing and …, 2009 – liebertonline.com
Aims: The aim of this study was to investigate if dried blood spot (DBS) samples stored in the
Danish Neonatal Screening Biobank (DNSB) and the Danish National Birth Cohort (DNBC) repository
are useful for Illumina single- nucleotide polymorphism (SNP) genotyping. Genomic DNA (
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…, S Toft, J Grove, DE Schendel, P Thorsen – Journal of autism and …, 2010 – Springer
Marlene B. Lauritsen Æ Meta Jørgensen Æ Kreesten M. Madsen Æ Sanne Lemcke Æ
Susanne Toft Æ Jakob Grove Æ Diana E. Schendel Æ Poul Thorsen Published online:
1 September 2009 © Springer Science+Business Media, LLC 2009
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…, HJ Møller, S Cliver, P Thorsen… – American journal of …, 2006 – Elsevier
Of the 61 women, 26% had >1 previous spontaneous preterm delivery; 84% were black; 87%
were unmarried; 13% were smokers, and 39% were delivered before 37 weeks of gestation.
Neither relaxin (median, 368 ng/L; range, 83-1493 ng/L) nor soluble CD163 (2.4 mg/L;
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IDA VOGEL, H GRØNBAEK, P THORSEN… – In Vivo, 2004 – iv.iiarjournals.org
Abstract. Objective: To examine vaginal insulin-like growth factor binding protein 1 (IGFBP-1)
as a marker of preterm delivery, amniotic fluid leakage or vaginal infection. Materials and
Methods: The material consisted of a nested case-control study (67 with idiopathic
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[PDF] from peerproject.euMV Hollegaard, P Thorsen… – …, 2009 – Wiley Online Library
Stored surplus of dried blood spot (DBS) samples from neonatal screening programs constitute
a vast potential for large genetic epidemiological studies. However, age of the samples and the
small amounts of DNA available may limit their usage. In this study we validate
Cited by 4Related articlesAll 7 versions

MV Hollegaard, J Grove, P Thorsen… – Acta obstetricia et …, 2008 – Wiley Online Library
Objective. To investigate the relation between 19 selected single nucleotide polymorphisms
in three cytokine genes, tumor necrosis factor alpha (TNFA), interleukin 1-beta (IL1B) and interleukin
6 (IL6) and preterm birth (<37 weeks’ gestation). Design. Case-control association study.
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…, J Lamoureux, K Skogstrand, P Thorsen – Cytokine, 2010 – Elsevier
Most previous studies of maternal cytokines and preterm birth have analyzed immunologic biomarkers
after the onset of labor or membrane rupture; fewer have examined the systemic (blood) immune
response prior to labor onset. We carried out a case–control study nested in a large (n =
Cited by 4Related articlesAll 6 versions

[CITATION] Risk factors for autism: perinatal factors, parental psychiatric history, and socioeconomic status

…, V Mogens, O Anne, A Esben, S Diana, T Poul… – Am J Epidemiol, 2005
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…, M Vestergaard, P Uldall, P Thorsen – … of Obstetrics & …, 2008 – Wiley Online Library
Objective To investigate the association of asphyxia-related conditions (reducing blood flow
or blood oxygen levels in the fetus) with spastic cerebral palsy (CP) considering different gestational
age groups and the timing of risk. Setting Danish Cerebral Palsy Register in eastern
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P Thorsen, BR Moller, M Arpi, A Bremmelgaard… – Lancet, 1994 – cat.inist.fr
Titre du document / Document title. PASTEURELLA AEROGENES ISOLATED FROM
STILLBIRTH AND MOTHER. Auteur(s) / Author(s). THORSEN P. ; MOLLER BR ; ARPI
M. ; BREMMELGAARD A. ; FREDERIKSEN W. ; Revue / Journal Title.
Cited by 5Related articlesBL DirectAll 4 versions

…, P Uldall, E Ernst, B Jacobsson, P Thorsen – Human …, 2010 – ESHRE
RESULTS There were 33 139 (5.6%) children born in Denmark from 1995 to 2003 as a result
of assisted conception and through to June 2009, 1146 (0.19%) children received a CP
diagnosis. Children born after assisted conception had an increased risk of a CP
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[CITATION] Die Hypnose im Dienste der Menschbeit

P Thorsen – 1960
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[CITATION] Eget sygesikringsbevis til børn. Nye muligheder for epidemiologisk forskning i den primære sundhedssektor

…, S Reusch, M Sørensen, H Thorsen – Ugeskrift for læger, 1999 – unknown
Cited by 1Related articlesBL Direct

P Thorsen, H Dybdahl, H Søgaard… – European Journal of …, 1991 – Elsevier
European Journal of Obstetrics & Gynecology and Reproductive Biology, 40 (1991) 67-11 0
1991 Elsevier Science Publishers BV 0028-2243/91/$03.50 EUROBS 01087 61 Ovarian tumors
caused by metastatic tumors of the appendix; two case reports Poul Thorsen, Helle
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[CITATION] Eta krestomatio

…, P Thorsen – 1944 – Esperanto-Forlaget SEFO
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[PDF] from ugeskriftet.dkSKP Sandager, I Vogel, P Thorsen… – UGESKR LÆGER, 2003 – ugeskriftet.dk
Litteratur 1. Jørgensen FS. Organisation af obstetrisk ultralyd i Danmark 1990. Ugeskr Læger
1992;154:2898-905. 2. Jørgensen FS. Ultralydundersøgelse af gravide kvinder i Danmark
1989-1990. Ugeskr Læger 1993;155:1627-32. 3. Jørgensen FS. Organisation af
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[CITATION] Bliv gammel uden at ældes

P Thorsen – 1954 – Capser Nielsens Forlag
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[CITATION] Presse, penge og politik 1839-48: Den sidste enevoldskonges forhold til konservative pressekredse–især i København

P Jensen – 1971 – Københavns Universitets Fond til …
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[PDF] from aau.dkG Thorsen, B Knudsen, P Panduro… – 2000 – vbn.aau.dk
13lhNGM-2000, Helsinki Наг lers aktivitet indflydelse pá risikoen for udt0rringsskader? Grete
Thorsen Aalborg Universitet, Aalborg, Danmark B0rge Knudsen Geoteknisk Institut, Ârhus, Danmark
Poul Panduro Vejdirektoratet, Skanderborg, Danmark Sten Thorsen Thorsen Geoteknik,
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P Videbech
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[CITATION] Thorkil Kristensen: en ener i dansk politik

PN Andersen – 1994 – Odense universitetsforlag
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[PDF] from utdallas.edu…, D Hougaard, A Børglum, P Thorsen… – Journal of Neural …, 2009 – Springer
as a candidate gene for autism Henriette Nørmølle Buttenschøn Æ Marlene Briciet Lauritsen
Æ Agata El Daoud Æ Mads Hollegaard Æ Meta Jorgensen Æ Kristine Tvedegaard Æ David
Hougaard Æ Anders Børglum Æ Poul Thorsen Æ Ole Mors
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…, TB Henriksen, LT Goldsmith, P Thorsen… – American journal of …, 2009 – Elsevier
We conducted a case-control study within a cohort of 1080 singleton pregnant women. In all,
38 women (3.5%) delivered spontaneously preterm (< 37 completed weeks of gestation). Relaxin
was measured in serum in gestational weeks 12 and 19, cervical length only in week 19.
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[PDF] from hindawi.comI Vogel, P Thorsen, B Jeune… – … in Obstetrics and …, 2006 – downloads.hindawi.com
1 NANEA, Department of Epidemiology, Institute for Public Health, University of Aarhus, 8000
Aarhus C, Denmark 2 Department of Clinical Genetics, Aarhus University hospital, 8000 Aarhus
C, Denmark 3 Institute of Public Health, University of Southern Denmark, 5000 Odense C,
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AE Curry, P Thorsen, C Drews… – Acta obstetricia et …, 2009 – Wiley Online Library
Objective. To examine associations between first-trimester plasma cytokines and spontaneous
preterm delivery (sPTD). Design. A case-control study was nested within the Danish National
Birth Cohort, a cohort of women with 101,042 pregnancies from 1997 to 2002 who were
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[CITATION] Comparison of biochemical profiles of vaginal fluid in BV-positive pregnant US versus european women

S Cauci, P Thorsen… – American Journal of Obstetrics and …, 2003 – Elsevier
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…, C Sværke, E Ernst, P Thorsen – … of Epidemiology and …, 2010 – jech.bmj.com
Contributors DH, PT and JG were responsible for conception and design. DH, JG and CS conducted
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manuscript. All authors provided critical input at all stages and critically reviewed and
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[CITATION] Time trends in the reported childhood diagnoses of neuropsychiatric disorders: a Danish cohort study

…, S Dalsgaard, PH Thomsen, P Thorsen – Archives of Pediatrics & …, 2007 – unknown
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[HTML] from nih.gov…, A Das, BJ Stoll, RD Higgins, P Thorsen… – Pediatric …, 2010 – ncbi.nlm.nih.gov
Matrix metalloproteinases (MMP) and chemokines appear to be induced by hyperoxia in preclinical
studies. We hypothesized that O 2 exposure immediately after birth is associated with altered
blood spot MMP 9 and β chemokine concentrations. The following analytes were
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[CITATION] Bacterial Vaginosis in Pregnancy: A Population-based Study

P Thorsen – 1998 – afhandling.
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S Hollegaard, I Vogel, P Thorsen, IP Jensen… – In Vivo, 2007 – iv.iiarjournals.org
Abstract. Background: Potential associations between current or previous C. trachomatis infections
(general IgG and serovars) and spontaneous preterm birth (PTB) were examined and associations
between C. trachomatis infections and previous fertility problems were explored. Patients
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[HTML] from oxfordjournals.org…, LA Schieve, E Ernst, J Olsen, P Thorsen – Human …, 2009 – ESHRE
RESULTS In the DNBC, assisted conception was reported with a sensitivity of 83% and positive
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[PDF] from dtuavisen.dkP Fritzel… – 1995 – dtuavisen.dk
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HCM Thorsen, G Zubieta-Calleja… – Research in Sports …, 2007 – informaworld.com
Research in Sports Medicine, 15: 225–239, 2007 Copyright © Taylor & Francis Group, LLC ISSN
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New Study – Flu Vaccine Doesn’t Work

A new study confirms yet again what many prior studies have shown [see list at end], that ‘flu vaccination is largely ineffective [despite what Government “health” officials want you to believe – but where of course will they be looking for their next job when they retire at 50 on generous government pensions]:  Jefferson T, et al. Vaccines for preventing influenza in healthy adults (Review). Cochrane Database Syst Rev. 2010 Jul 7;(7):CD001269.

Read also here on CHS how Flu Vaccine Caused 3587 US Miscarriages & StillbirthsUsing the US Vaccine Adverse Event Reporting System (VAERS), including updates through July 11, 2010 as a second ascertainment source, capture-recapture statistical methods were used to estimate the true number of miscarriages and stillbirths following A-H1N1 flu vaccination in the U.S.

Julie Gerberding head of the US Centres for Disease Control – budget US$11 billion – the US agency charged with promoting vaccines [CDC] following her removal by President Obama went directly to become vaccine maker Merck’s Director of Vaccines Division in December 2009: Dr. Julie Gerberding Named President of Merck Vaccines21 Dec 2009 – Merck & Co., Inc.

Here’s a plain language summary of the Oxford based Cochrane Collaboration recent study in the authors’ own words:

Over 200 viruses cause influenza and influenza-like illness which produce the same symptoms (fever, headache, aches and pains, cough and runny noses). Without laboratory tests, doctors cannot tell the two illnesses apart. Both last for days and rarely lead to death or serious illness. At best, vaccines might be effective against only influenza A and B, which represent about 10% of all circulating viruses. Each year, the World Health Organization recommends which viral strains should be included in vaccinations for the forthcoming season.

Authors of this review assessed all trials that compared vaccinated people with unvaccinated people. The combined results of these trials showed that under ideal conditions (vaccine completely matching circulating viral configuration) 33 healthy adults need to be vaccinated to avoid one set of influenza symptoms. In average conditions (partially matching vaccine) 100 people need to be vaccinated to avoid one set of influenza symptoms. Vaccine use did not affect the number of people hospitalised or working days lost but caused one case of Guillian-Barré syndrome (a major neurological condition leading to paralysis) for every one million vaccinations. Fifteen of the 36 trials were funded by vaccine companies and four had no funding declaration. Our results may be an optimistic estimate because company-sponsored influenza vaccines trials tend to produce results favorable to their products and some of the evidence comes from trials carried out in ideal viral circulation and matching conditions and because the harms evidence base is limited.

The authors warn that industry-funded studies are more likely to be unreliable but be published in prestigious journals and cited more frequently than more reliable independent studies. Here’s what they say:

WARNING:
This review includes 15 out of 36 trials funded by industry (four had no funding declaration). An earlier systematic review of 274 influenza vaccine studies published up to 2007 found industry funded studies were published in more prestigious journals and cited more than other studies independently from methodological quality and size. Studies funded from public sources were significantly less likely to report conclusions favorable to the vaccines. The review showed that reliable evidence on influenza vaccines is thin but there is evidence of widespread manipulation of conclusions and spurious notoriety of the studies. The content and conclusions of this review should be interpreted in light of this finding.

And here are some earlier studies:-

__________________

And here is a more extensive list:-

Vaccines for preventing influenza in healthy adults.

Jefferson T, Di Pietrantonj C, Rivetti A, Bawazeer GA, Al-Ansary LA, Ferroni E.

Cochrane Database Syst Rev. 2010 Jul 7;(7):CD001269. Review.PMID: 20614424 [PubMed – indexed for MEDLINE]Related citations

Vaccines for preventing influenza in healthy adults.

Jefferson TO, Rivetti D, Di Pietrantonj C, Rivetti A, Demicheli V.

Cochrane Database Syst Rev. 2007 Apr 18;(2):CD001269. Review. Update in: Cochrane Database Syst Rev. 2010;7:CD001269. PMID: 17443504 [PubMed – indexed for MEDLINE]Related citations

Demicheli V, Rivetti D, Deeks JJ, Jefferson TO.

Cochrane Database Syst Rev. 2004;(3):CD001269. Review. Update in: Cochrane Database Syst Rev. 2007;(2):CD001269. PMID: 15266445 [PubMed – indexed for MEDLINE]Related citations

Demicheli V, Rivetti D, Deeks JJ, Jefferson TO.

Cochrane Database Syst Rev. 2001;(4):CD001269. Review. Update in: Cochrane Database Syst Rev. 2004;(3):CD001269. PMID: 11687102 [PubMed – indexed for MEDLINE]Related citations

Jefferson T, Di Pietrantonj C, Al-Ansary LA, Ferroni E, Thorning S, Thomas RE.

Cochrane Database Syst Rev. 2010 Feb 17;(2):CD004876. Review.PMID: 20166072 [PubMed – indexed for MEDLINE]Related citations

Smith S, Demicheli V, Di Pietrantonj C, Harnden AR, Jefferson T, Matheson NJ, Rivetti A.

Cochrane Database Syst Rev. 2006 Jan 25;(1):CD004879. Review. Update in: Cochrane Database Syst Rev. 2008;(2):CD004879. PMID: 16437500 [PubMed – indexed for MEDLINE]Related citations

Jefferson T, Rivetti A, Harnden A, Di Pietrantonj C, Demicheli V.

Cochrane Database Syst Rev. 2008 Apr 16;(2):CD004879. Review.PMID: 18425905 [PubMed – indexed for MEDLINE]Related citations

Rivetti D, Jefferson T, Thomas R, Rudin M, Rivetti A, Di Pietrantonj C, Demicheli V.

Cochrane Database Syst Rev. 2006 Jul 19;3:CD004876. Review. Update in: Cochrane Database Syst Rev. 2010;2:CD004876. PMID: 16856068 [PubMed – indexed for MEDLINE]Related citations

Demicheli V, Rivetti D, Deeks JJ, Jefferson TO.

Cochrane Database Syst Rev. 2000;(2):CD001269. Review. Update in: Cochrane Database Syst Rev. 2001;(4):CD001269. PMID: 10796628 [PubMed – indexed for MEDLINE]Related citations

Gerstoft J.

Ugeskr Laeger. 2001 May 7;163(19):2615-7. Danish. PMID: 11360353 [PubMed – indexed for MEDLINE]Related citations

Thomas RE, Jefferson T, Demicheli V, Rivetti D.

Cochrane Database Syst Rev. 2006 Jul 19;3:CD005187. Review. Update in: Cochrane Database Syst Rev. 2010;2:CD005187. PMID: 16856082 [PubMed – indexed for MEDLINE]Related citations

Poole PJ, Chacko E, Wood-Baker RW, Cates CJ.

Cochrane Database Syst Rev. 2006 Jan 25;(1):CD002733. Review.PMID: 16437444 [PubMed – indexed for MEDLINE]Related citations

Marshall M, Crowther R, Almaraz-Serrano A, Creed F, Sledge W, Kluiter H, Roberts C, Hill E, Wiersma D, Bond GR, Huxley P, Tyrer P.

Health Technol Assess. 2001;5(21):1-75. Review.PMID: 11532238 [PubMed – indexed for MEDLINE]Free ArticleRelated citations

Dear K, Holden J, Andrews R, Tatham D.

Cochrane Database Syst Rev. 2003;(4):CD000422. Review. Update in: Cochrane Database Syst Rev. 2008;(1):CD000422. PMID: 14583920 [PubMed – indexed for MEDLINE]Related citations

Thomas RE, Jefferson T, Lasserson TJ.

Cochrane Database Syst Rev. 2010 Feb 17;(2):CD005187. Review.PMID: 20166073 [PubMed – indexed for MEDLINE]Related citations

Cates CJ, Jefferson TO, Rowe BH.

Cochrane Database Syst Rev. 2008 Apr 16;(2):CD000364. Review.PMID: 18425863 [PubMed – indexed for MEDLINE]Related citations

Demicheli V, Jefferson T, Rivetti D, Deeks J.

Vaccine. 2000 Jan 6;18(11-12):957-1030. Review.PMID: 10590322 [PubMed – indexed for MEDLINE]Related citations

Dharmaraj P, Smyth RL.

Cochrane Database Syst Rev. 2009 Oct 7;(4):CD001753. Review.PMID: 19821281 [PubMed – indexed for MEDLINE]Related citations

Cates CJ, Jefferson TO, Bara AI, Rowe BH.

Cochrane Database Syst Rev. 2000;(4):CD000364. Review. Update in: Cochrane Database Syst Rev. 2004;(2):CD000364. PMID: 11034684 [PubMed – indexed for MEDLINE]Related citations

Moberley SA, Holden J, Tatham DP, Andrews RM.

Cochrane Database Syst Rev. 2008 Jan 23;(1):CD000422. Review.PMID: 18253977 [PubMed – indexed for MEDLINE]Related citations

Small Pox – Big Lie – Bioterrorism Implications of Flawed Theories of Eradication

Our governments and their security advisors base their strategies for dealing with claimed threats of smallpox bio-terrorism on flawed theories and “science” when effective proven strategies are ignored. The national and international security implications are profound.

Smallpox is claimed to have been eradicated by “ring vaccination” but the theory of ring vaccination is flawed. It is confounded by three factors: [“confounding”: definition]. All these factors are known and one of which was proven in Leicester England between 1882 and 1908 by abandoning vaccination. Ring vaccination relies on isolation of cases to prevent spread of the disease.

Smallpox was eradicated in reality by three mechanisms, none of which depended on vaccination for their efficacy: isolation, attenuation and improved living conditions, particularly nutrition and sanitation.The effect cannot be attributable to the smallpox vaccine – any vaccine which takes over 100 years to work ipso facto proves itself not to have.

“Ring vaccination” depended on isolation.  It is the use of isolation and the experience of Leicester, England which confound the claims that smallpox was eradicated by vaccination.  The vaccine had not “worked” in over a century of use.

Leicester proved in a dramatic and successful experiment that isolation is effective, less expensive and that the smallpox vaccine programme did not work. Leicester reduced smallpox mortality dramatically using isolation of cases.  In the rest of England and other countries,  deaths continued to mount despite mass vaccination campaigns [see more below].  Full details can be read in “LEICESTER: Sanitation versus Vaccination” By J.T. Biggs J.P. [Download Entire Book as .pdf 43 Mb  – Or Read Online].  Extracts from the book appear below.

The theory and data upon which ring vaccination is based has been questioned by academics from Yale and Stanford universities: Smallpox Eradication in West and Central Africa: Surveillance-Containment or Herd Immunity? Edward H. Kaplan, PhD* and Lawrence M. Wein, PhD†.  Kaplan and Wein come to a flawed conclusion regarding the more appropriate mechanisms but their analysis shows the ring vaccination theory is at the least questionable.  Their work was discussed in Science journal: New Look at Old Data Irks Smallpox-Eradication Experts–MARTIN ENSERINK – SCIENCE VOL 299 10 JANUARY 2003.

Smallpox naturally attenuated to a strain called “Alastrim” or “variola minor” which was first recognised in Florida and South America in the late 19th century: Alastrim Smallpox Variola Minor Virus Genome DNA Sequences Virology Volume 266, Issue 2, 20 January 2000, Pages 361-386.

Attenuation is the natural process by which many diseases over time have become less severe until they either vanish or become of minimal concern. The dramatic effect of attenuation for various diseases combined with a third factor, steadily improving living conditions, can be seen in the data collected here: Vaccines Did Not Save Us – 2 Centuries of Official Statistics.

In the zeal to claim vaccines are so important to human health, with all the economic benefits to the medical professions from the procedure, vaccinology became and has remained a “science-free zone” where smallpox vaccine and theories of eradication of smallpox are concerned.

In 1967, the World Health Organization launched the Intensified Smallpox Eradication Program. Events in Nigeria stimulated adoption of ring vaccination when an outbreak developed among a religious sect. Faced with limited resources, staff isolated infected individuals and vaccinated others. This was the method of surveillance and containment which became known as “ring vaccination” and was adopted as a worldwide standard: 1) Henderson DA, Inglesby TV, Bartlett JG, Ascher MS, Eitzen E, Jahrling PB, et al. Smallpox as a Biological Weapon. In: Henderson DA, Inglesby TV, O’Toole T, ed. Bioterrorism: Guidelines for Medical and Public Health Management. 2002: Chicago, IL: AMA Press. 2002.99-120. 2) Hopkins JW. The eradication of smallpox: organizational learning and innovation in international health administration. J Dev Areas.1988;22(3):321-32.

Clearly, as was proven in the City of Leicester, it can only have been the isolation and not the vaccination which was responsible for ultimately eradicating smallpox as it was known, together with attenuation and improved living conditions.  Whether smallpox was eradicated or whether it remains in different manifestations  like  human “monkey pox” has been a matter of debate: HUMAN MONKEYPOX AND OTHER POXVIRUS INFECTIONS OF MAN: Chapter 29 SMALLPOX AND ITS ERADICATION;  Clinical manifestations of human monkeypox influenced by route of infection The Journal of infectious diseases2006, vol. 194, no6, pp. 773-780: Levine RS, Peterson A, Yorita KL, Carroll D, Damon IK, et al. 2007 Ecological Niche and Geographic Distribution of Human Monkeypox in Africa. PLoS ONE 2(1): e176. doi:10.1371/journal.pone.0000176.

The following are some extracts from “LEICESTER: Sanitation versus Vaccination” By J.T. Biggs J.P. [Download Entire Book as .pdf 43 Mb  – Or Read Online].

[Click here to continue reading more from the above passage.]

[Click here to continue reading more from the above passage.]

TABLE 21

SMALLPOX FATALITY RATES, cases in vaccinated and re-vaccinated populations compared with “unprotected” Leicester – 1860 to 1908.

Name. Period. Small-Pox.  Cases Small-Pox. Deaths. Fatality-rate per cent. of Cases
Japan 1886-1908 288,779 77,415 26.8
British Army (United Kingdom) 1860-1908 1,355 96 7.1
British Army (India) 1860-1908 2,753 307 11.1
British Army (Colonies) 1860-1908 934 82 8.8
Royal Navy 1860-1908 2,909 234 8.0
Grand Totals and case fatality rate per cent, over all 296,730 78,134 26.3
Leicester (since giving up vaccination) 1880-1908 1,206 61 5.1

Biggs saidIn this comparison, I have given the numbers of revaccinated cases, and deaths, and each fatality-rate separately and together, so that they may be compared either way with Leicester. In pro-vaccinist language, may I ask, if the excessive small-pox fatality of Japan, of the British Army, and of the Royal Navy, are not due to vaccination and revaccination, to what are they due? It would afford an interesting psychical study were we able to know to what heights of eloquent glorification Sir George Buchanan would have soared with a corresponding result—but on the opposite side.

TABLE 29.

Small-Pox Epidemics, Cost, and Fatality Rates Compared

Vaccinal Condition Small-Pox Cases Small-Pox Deaths Fatality-rate Per Cent Cost of Epidemic
London 1900-02 Well Vaccinated 9,659 1,594 16.50 £492,000
Glasgow 1900-02 Well Vaccinated 3,417 377 11.03 £ 150,000
Sheffield 1887-88 Well Vaccinated 7,066 688 9.73 £32,257
Leicester 1892-94 Practically Unvaccinated 393 21 5.34 £2,888
Leicester 1902-04 Practically Unvaccinated 731 30 4.10 £1,602
City of Leicester Smallpox Deaths 1880-1908

The following graphs [not from J T Biggs’ book – but sources cited] also illustrate how attenuation of smallpox resulted in greatly reduced mortality in England and the USA.

This graph shows the deaths resulting not from smallpox but from the vaccine and its effects:-

[Click Graph to Enlarge – Opens In New Window]

uk-vacc-deaths-1875-1922

And in this graph we can see how deaths from the vaccine often equalled or exceeded death from smallpox.

[Click Graph to Enlarge – Opens In New Window]

uk-vacc-deaths-1906-1922

The following graph shows how smallpox mortality was largely unaffected by the vaccine programme.  It continued in epidemics for decades and started to diminish as the effects of the Industrial Revolution in the latter part of the 19th Century provided more money to middle and working classes:-

[Click Graph to Enlarge – Opens In New Window]

uk-smallpox-1838-1890

Flu Vaccine Caused 3587 US Miscarriages & Stillbirths

Link to this page http://tinyurl.com/3ydy9zh

CDC alleged to have ignored up to 3,587 Miscarriages from H1N1 Vaccine

A shocking report from the National Coalition of Organized Women (NCOW) presented data from two different sources demonstrating that the 2009/10 H1N1 vaccines contributed to an estimated 1,588 miscarriages and stillbirths.  A corrected estimate may be as high as 3,587 cases.  NCOW also highlights the disturbing fact that the CDC failed to inform their vaccine providers of the incoming data of the reports of suspected H1N1 vaccine related fetal demise.

Dr. Marie McCormick, chair of the H1N1 Vaccine Risk and Assessment Working Group, said at the 3rd conference-the National Vaccine Advisory Committee (NVAC) that there were absolutely no H1N1 vaccine-related adverse events in pregnant women in 2009/10, directly contradicting the publicly available evidence.

This is not the first time McCormick has done this [see  detailed evidence below]. McCormick is hired because, using US tax dollars, she can be relied to do the wrong thing for the American people but the “right thing” for her bosses. McCormick is a tool of those who hire her.

NCOW collected the data from pregnant women (age 17-45 years) that occurred after they were administered a 2009 A-H1N1 flu vaccine. The raw data is available on the website.

Using the Vaccine Adverse Event Reporting System (VAERS), including updates through July 11, 2010 as a second ascertainment source, capture-recapture statistical methods* were used to estimate the true number of miscarriages and stillbirths following A-H1N1 flu vaccination in the U.S. Typically, even so-called “complete” studies conducted by the CDC have been shown to miss from 10% to 90% of the actual cases because of under-reporting.

The statistical method employed is an expeditious and cost effective method of attempting to ascertain a complete count of all cases when two or more ascertainment sources (VAERS and NCOW survey) have failed to collect all the existing cases. Overall, this approach shows that approximately only 15% of the occurrences of a miscarriage or stillbirth were actually reported.

The corrected estimate for the total number of 2009-A-H1N1-flu-shot-associated miscarriages and stillbirths during the 2009/10-flu season is 1,588 (95% goodness-of-fit confidence interval, 946 to 3587). That is, the lower and upper range-probability of miscarriage and stillbirths due to the H1N1 vaccine was as low as 946 and as high as 3,587.

Eileen Dannemann, Director of NCOW, presented the findings for the second time to Dr. Marie McCormick, chair of the Vaccine Risk and Assessment Working Group, during the Advisory Commission on Childhood Vaccines (ACCV) meeting, Sept 3, 2010. Just prior to Ms. Dannemann’s presentation Dr. McCormick, had pronounced that there were absolutely no H1N1 vaccine-related adverse events in pregnant women in 2009/10, directly contradicting the evidence publicly available.

The very next week at the Sept 14th National Vaccine Advisory Committee (NVAC) meeting Dr. McCormick, (despite having been informed on two previous occasions of the VAERS data) pronounced, once again, that there were no adverse events in pregnant women. At the conclusion of the NVAC meeting, during public comment, Dannemann submitted the data again.

McCormick has done this before.

If a criminal recklessly discharges a firearm in the street that can be an offense of reckless endangerment.  If a Federal Health official recklessly ignores plain evidence putting women and unborn children at risk and also causing miscarriages and stillbirths what should the penalty be?  Are life sentences or death penalties appropriate for McCormick and her bosses? They should all face stiff penalties.

Consider the following evidence from a Texas legal case and then ask yourself: “What is the difference between hiring Dr Marie McCormick to sit on one of these vaccine safety committees and hiring her to discharge indiscriminately an M240 machine  gun into a baseball stadium crowd of pregnant school moms and kids“.

Law firm Waters & Kraus produced in a Texas Court a closed session transcript of a US Institutes of Medicine Committee chaired by McCormick to investigate the link between vaccines and autism [On file in the US District Court of Texas, Eastern District; Case #5:03-CV-141]:

Dr. McCormick stated, “we are not ever going to come down that it is a true side effect,” before the committee had considered any evidence [page 97].

Dr. McCormick noted the US CDC “wants us to declare, well, these things are pretty safe on a population basis.” [page 33].

McCormick’s IoM committee colleague Dr. Stratton stated “the point of no return, the line we will not cross in public policy is to pull the vaccine, change the schedule. We could say it is time to revisit this but we will never recommend that level. Even recommending research is recommendations for policy.  We wouldn’t say compensate, we wouldn’t say pull the vaccine, we wouldn’t say stop the program.”[page 74]

And do vaccines cause autistic conditions?  If you read nothing else we strongly recommend you read this: PDF Download – Text of May 5th 2008 email from US HRSA to Sharyl Attkisson of CBS News].  In it the US Health Resources Services Administration [HRSA] state to CBS News reporter Sharyl Attkisson

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.

Despite all the lies and deceit by health official worldwide, the question “do vaccines cause autism” was answered after the Hannah  Poling story broke in the USA in February 2008 [see CHS article here].  Hannah developed an autistic condition after 9 vaccines administered the same day.  Under the media spotlight numerous US health officials and agencies conceded on broadcast US nationwide TV news from CBS and CNN. Full details with links to the original sources can be found in this CHS article: Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines. [Blue Text added 10 April 2011]

Excerpts and adaptation from speech delivered by Eileen Dannemann, Director, National Coalition of Organized Women Friday, September 3, 2010 to the Advisory Commission on Childhood Vaccines (ACCV) meeting.

“Initially, at the beginning of the H1N1 pandemic consequence management drill there were allegedly 30 maternal deaths.  It was these deaths that the CDC used as the basis to initiate a strenuous and aggressive campaign to vaccinate the pregnant population with the untested H1N1 vaccine.  The CDC ascertained that there were eventually a total of 56 maternal deaths (assuming the fetuses died with them).  Dr. Alicia Siston’s JAMA study (CDC) acknowledged that most of these deaths were ‘unconfirmed’ H1N1 virus caused deaths despite the fact that the CDC had tests that could have verified, for certain, that these were H1N1 related deaths.

Vaccine-related fetal demise reports from VAERS increased 2,440%–from 7 cases in 2007/8 to 178 in 2009/10. Seventy deaths reported from another source had 7 overlapping cases with VAERS, yielding 241 unique cases.  Simplistically speaking, it would have been 85 to 192 times safer not to vaccinate from the perspective of the in-utero child.

Considering that the total of 56 maternal deaths in Dr. Alicia’s Siston’s study, allegedly due to the H1N1 virus itself, are unverified and in light of the overwhelming adverse events reported, we emphasize that inoculating pregnant women with another untested vaccine containing a combination of components found in the offending 2009 H1N1 vaccine is insupportable. Thus, it must be argued that the CDC was grossly negligent to fail to inform their vaccine providers of the incoming VAERS data, while providers blindly followed the CDC “standard of care” guidelines to vaccinate every pregnant woman in 2009/10.  Furthermore, in the face of these findings and the purposeful withholding of these findings by CDC’s Dr. Marie McCormick and her vaccine risk assessment group, for the CDC’s Advisory Committee on Immunization Practices (ACIP) to recommend another iteration of the same vaccine to pregnant women in 2010/11 may be argued as more than gross negligence -but rather- an act of willful misconduct.

We strongly recommend that the CDC withdraws their continued recommendation to pregnant women, instead, strictly adhering to the FDA/manufacturers warning on the insert packages that the flu shot not be given to pregnant women unless clearly needed.  As well, we suggest that the CDC advise all Ob/Gyns, vaccine providers and the public this year, of last season’s VAERS reports on H1N1 vaccine-related fetal deaths” despite the fact that it may be contrary to CDC’s vaccine uptake performance goals”.

*Gary S. Goldman, Ph.D, author of various peer-reviewed medical journal publications, has verified the capture-recapture

(C-R) figures published in the NCOW report.  Dr. Goldman previously worked for 8 years as a Research Analyst for the L.A. County Department of Health Services in an epidemiological study project funded by the CDC.

Mercury & Autism – Naming and Shaming Dr Gorski & “Science Free Zone” Bloggers

… Who Have it Sooooo Wrong Once More

Almost funny if it was not so serious for childrens’ health and safety worldwide.  The usual same sad characters who are happy for mercury to be pumped into infants [neuro-toxic in parts per billion] crow over the junk science published in Pediatrics journal yesterday.

But the difference today is it is easy to show they are all uniformly wrong.

We name and shame the same “armchair web experts” and their instant science free analyses of “the government funded” study they proclaim is the last word in the issue of vaccines causing autistic conditions and brain damage in infants.

Sadly [for them] the study is palpable junk – “science free” and with it so are they and their analyses it would seem:- Mercury As A Cause of Autism – More Denialist Junk “Science” from Pediatrics Journal Posted September 14, 2010.

This is hardly surprising as this is a study funded by the US Centers for Disease Control [as we have shown before over another CDC funded study into mercury toxicity in vaccines: US Research Fraud, Tax Dollars And Italian Vaccine Mercury Study].

But today’s  example shows these desperate bloggers as incapable of independent analytical or scientific thought  [whether by choice or intellectual deficit we cannot say].

It is known and documented autistic childrens’ brains and other organs retain mercury when other childrens’ bodies do not.  The authors of this Pediatrics study carefully measured what went into all the children but not what did or did not come out of the non autistic compared to autistic.  So we cannot tell how much mercury the autistic children accumulated in their brains compared to the non autistic  children.   End result – another piece of hyped junk science that neither adds to nor takes away anything from what is already known.

For our readers pleasure, you can sample some “science free” ranting writing in these examples, led by the beneficiary of drug industry largesse himself ORAC, aka Dr David Gorski [David Gorski’s Financial Pharma Ties: What He Didn’t Tell You] and the inimitably misleading blog from Kev Leitch [Lies, Damn Lies and Blog Posts]:-

Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines

A New Scientist article 29 June 2010 by Jim Giles states:-

We still do not know what causes autism.

Desperate measures: The lure of an autism cure

That is not correct. Here we set out four ways autistic conditions are caused and confirmed by statements from the current President of pharmaceutical giant Merck’s Vaccines Division, by US Government agencies, by the US Federal Court and in formally published academic journal papers.

If you read nothing else we strongly recommend you read this PDF Download – Text of May 5th 2008 email from US HRSA to Sharyl Attkisson of CBS News].  In it the US Health Resources Services Administration [HRSA] state to CBS News reporter Sharyl Attkisson

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures. [Text added 10 April 2011]

The first known cause of autism was rubella virus. So not only is New Scientist an unreliable source of information, this cause of autism has been known since the 1960s. And rubella virus is one of the three live viruses in the MMR vaccine.

… rubella (congenital rubella syndrome) is one of the few proven causes of autism.”  Walter A. Orenstein, M.D. US as Assistant Surgeon General, Director National Immunization Program in a letter to the UK’s Chief Medical Officer 15 February 2002.

rubella virus is one of the few known causes of autism.” US Center for Disease Control.
“FAQs (frequently asked questions) about MMR Vaccine & Autism”  [ED 8/Apr/12: This is the web archive of the CDC page – you will need to search in or scroll down the page to see the text.  As papers cited on the original page by the CDC as evidence for no link with the vaccine have been steadily discredited it seems the CDC has decided to remove the page and it seems someone has been deleting the archived versions of the page from the web archive too].

rubella can cause autism The Pediatrician’s Role in the Diagnosis and Management of Autistic Spectrum Disorder in Children – PEDIATRICS Vol. 107 No. 5 May 2001

Journal references:

Chess, S. Autism in children with congenital rubella. J Autism Child Schizophr. 1, 33-47 (1971).

Chess S. Follow-up report on autism in congenital rubella. J Autism Child Schizophr. 1977;7:69 –81

Ziring PR. Congenital rubella: the teenage years. Pediatr Ann. 1997;6: 762–770

People who are pre-disposed to have a mitochondrial dysfunction can develop autistic conditions following vaccination.  The current President of Merck’s Vaccines Division, Julie Gerberding confirmed to CBS News when she was Director of the US Centres for Disease Control that:

Now, we all know that vaccines can occasionally cause fevers in kids. So if a child was immunized, got a fever, had other complications from the vaccines. And if you’re predisposed with the mitochondrial disorder, it can certainly set off some damage. Some of the symptoms can be symptoms that have characteristics of autism.

HOUSE CALL WITH DR. SANJAY GUPTA – Unraveling the Mystery of Autism; Talking With the CDC Director; Stories of Children with Autism; Aging with Autism – Aired March 29, 2008 – 08:30   ET

Mitochondrial dysfunction is claimed to be “rare” but is not.  It can apply to a minimum of 20% of cases.

And this was said when Gerberding was then head of the US Centres for Disease Control – budget US$11 billion.  It followed from  award winning author and journalist David Kirby breaking the story of the Hannah Poling case, secretly settled by the US Government.  It was after this story broke that it started to be acknowledged that autism has an “environmental” cause and is not solely an “internal” condition [ie not determined solely by genetics]: AUTISM – US Court Decisions and Other Recent Developments – It’s Not Just MMR

Gerberding went from the US agency charged with promoting vaccines [CDC] directly to become vaccine maker Merck’s Director of Vaccines Division: Dr. Julie Gerberding Named President of Merck Vaccines21 Dec 2009 – Merck & Co., Inc.

Autistic conditions can result from encephalopathy following vaccination.  The US Health Resources and Services Administration (HRSA) confirmed to CBS News that of 1322 cases of vaccine injury compensation settled out of court by the US Government in secret settlements:-

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.[PDF Download – Text of email from US HRSA to Sharyl Attkisson of CBS News]

CBS News Exclusive: Leading Dr.: Vaccines-Autism Worth Study Former Head Of NIH Says Government Too Quick To Dismiss Possible Link – WASHINGTON, May 12, 2008

Vaccine Case: An Exception Or A Precedent? – First Family To Have Autism-Related Case “Conceded” Is Just One Of Thousands – CBS News By Sharyl Attkisson WASHINGTON, March 6, 2008

Measles and mumps are two of the three live viruses in the MMR vaccine. Exposure to live measles or mumps viruses can cause encephalitis:-

measles and mumps can cause significant disability, including encephalitis

The Pediatrician’s Role in the Diagnosis and Management of Autistic Spectrum Disorder in Children – PEDIATRICS Vol. 107 No. 5 May 2001

So there is direct evidence that live measles, mumps or rubella viruses separately can cause encephalitis leading to autism.

More troubling is that this has been known for a long time.  So the risks of giving very young children a vaccine containing three live viruses all at once were known. These two World Health Organisation papers published nearly 40 years ago set out the hazards:

Virus-associated immunopathology : animal models and implications for human disease”:

1. Effects of viruses on the immune system, immune-complex diseases, and antibody-mediated immunologic injury Bulletin of The World Health Organisation. 1972; 47(2): 257-264.

2. Cell-mediated immunity, autoimmune diseases, genetics, and implications for clinical research Bulletin of the World Health Organisation. 1972; 47(2): 265-274.

Autistic conditions can result from acute disseminated encephalomyelitis (ADEM) following MMR vaccination as held by the US Federal Court in the case of Bailey Banks.  In his conclusion, US Federal Court Special Master Abell ruled that Petitioners had proven that the MMR had directly caused a brain inflammation illness called acute disseminated encephalomyelitis (ADEM) which, in turn, had caused the autism spectrum disorder PDD-NOS in the child:

The Court found that Bailey’s ADEM was both caused-in-fact and proximately caused by his vaccination. It is well-understood that the vaccination at issue can cause ADEM, and the Court found, based upon a full reading and hearing of the pertinent facts in this case, that it did actually cause the ADEM. Furthermore, Bailey’s ADEM was severe enough to cause lasting, residual damage, and retarded his developmental progress, which fits under the generalized heading of Pervasive Developmental Delay, or PDD [an autism spectrum disorder]. The Court found that Bailey would not have suffered this delay but for the administration of the MMR vaccine, and that this chain of causation was… a proximate sequence of cause and effect leading inexorably from vaccination to Pervasive Developmental Delay.

[Banks v. HHS (Case 02-0738V, 2007 U.S. Claims LEXIS 254, July 20, 2007)].

And what does not cause autism?

Autism is not “caused” by “genes”

Dr Francis S. Collins, M.D., Ph.D. the 16th and current Director of the US$30.5 billion budget National Institutes of Health [nominated by President Obama: NIH News Release 17th August 2009 ] stated in evidence to US House of Representatives Committee May 2006 when Director of the US National Human Genome Research Institute:

Recent increases in chronic diseases like diabetes, childhood asthma, obesity or autism cannot be due to major shifts in the human gene pool as those changes take much more time to occur. They must be due to changes in the environment, including diet and physical activity, which may produce disease in genetically predisposed persons.

Francis S. Collins, M.D., Ph.D. evidence to US House of Representatives Committee May 2006

Collins controls the US $30.5 billion annual medical research budget and is a leading medical doctor and geneticist who led the Human Genome Project.

Autistic conditions affect 1 in 100 US children.  They affect 1 in 64 British children [1 in 40 are boys] according to a Cambridge University study.

ESTIMATING AUTISM SPECTRUM PREVALENCE IN THE POPULATION: A SCHOOL BASED STUDY FROM THE UK

Conclusions: The prevalence estimate of known cases of ASC, using different methods of ascertainment converges around 1%. The ratio of known to unknown cases means that for every three known cases there are another two unknown cases. This has implications for planning diagnostic, social and health services.”

It is estimated to cost the UK £28 billion per annum [roughly US$42 billion]: [“Economic Consequences of Autism in the UK” – London School of Economics – Study by team led by Professor Martin Knapp [Executive Summary]

US MMR Litigation – The Truth – And Was Dr Stephen Bustin A Reliable Witness?

….. this is the story of the illegal behaviour of the US Department of Justice in the Michelle Cedillo case.  And how the English and US Federal Courts acted to torpedo one severely injured little girl’s claim for much needed financial compensation – and with it over 5000 other US childrens’ cases.

Who & Why

This is about how the might of the US Government and others was brought to bear to  do all they could to destroy this brave child’s chance of recompense for severe injuries caused by vaccines. And Michelle’s crime? She is living evidence supporting what has been called the “discredited”  Wakefield hypothesis.

If her case was allowed to succeed it would have been the first demonstration that Wakefield was onto something and that children could suffer severe chronic ill-health as a result of an ever increasing childhood vaccination schedule.

Michelle has a substantial inflammation level (“SIL”) and medical evidence showed high levels of measles virus in her body.  So if the Wakefield hypothesis was to be discredited, it was crucial to destroy this little girl’s case by whatever means were available. Michelle had expert opinions supported by scientific literature.  The US Government and its 17 experts provided no evidence of an alternate cause of Michelle’s injuries.

Her appeal to the US Federal Court of Appeals was heard on 10th June 2010 and judgement of the US Appeal Court is pending.

Her case was turned into a test case for thousands of American children who have autism, inflammatory bowel disease and other medical problems caused by vaccines.

The following account is researched from US court documents filed in the case, English court documents [supposedly “public-domain” but no one is being told about them and what they contain], from published formal journals and other public sources.

What Did Wakefield Say

Dr Andrew Wakefield’s research implicated the MMR vaccine.  The research was of the known medical literature and of  clinical cases of children investigated after injury from receiving the measles mumps and rubella triple vaccine.  They were treated at the internationally renowned Royal Free Hospital, London, England.  Wakefield demonstrated that the MMR vaccination is a biologically plausible risk for inflammatory bowel disease, autism or other immune-mediated diseases.

The Wakefield hypothesis is based on sound known medical science.  Something not easy to “discredit”, [by legitimate means that is].  The known virological and immunological evidence shows that it is both biologically plausible and consistent with temporal trends.   It was and remains legitimate to hypothesize that the combination of three viruses that have been associated both independently and in combination with autism, may represent – through mechanisms that are not yet fully understood – a  compound risk for the disorder.

The hazards of viral infection to genetically susceptible individuals have been long known.  So the risks of giving very young children a vaccine containing three live viruses were predictable. These two World Health Organisation papers published nearly 40 years ago set this out: “Virus-associated immunopathology : animal models and implications for human disease”: 1. Effects of viruses on the immune system, immune-complex diseases, and antibody-mediated immunologic injury Bulletin of The World Health Organisation. 1972; 47(2): 257-264.  2. Cell-mediated immunity, autoimmune diseases, genetics, and implications for clinical research Bulletin of the World Health Organisation. 1972; 47(2): 265-274.

How to Kill Michelle’s Case

If Michelle’s case was to be harmed, it was essential to cast doubt on the evidence of the presence of measles virus in her body.  The evidence was from testing in the Unigenetics Laboratory in Dublin, Ireland by Professor John O’Leary.

The problem for the US Federal Court appears to have been that Michelle presented unrebuttable evidence that the O’Leary lab’s test results were reliable with respect to patients like Michelle with a SIL. A SIL lab result is also referred to as one “with high copy numbers”.

The only dispute about the reliability of the O’Leary lab’s test results was those for minimal inflammation levels (“MILs”) and not for those like Michelle with SIL’s. “MIL” results are ones where inaccuracy is inherent in the process because of the low copy numbers and the iterations involved in achieving them, against inevitable background contamination found in all such labs.

The critical evidence for Michelle included the testimony of Michelle’s experts, the evidence the US Government submitted by Dr. Oldstone, and a dramatic concession by a last minute US Government witness, Dr. Stephen Bustin. At the hearing  Dr. Bustin conceded that  other laboratory results from Dr. Cottor’s lab were consistent with the O’Leary lab’s results for samples with SILs.

The US Federal Court Special Master ignored this evidence at trial.

Then on the initial appeal the appeal judge, Judge Wheeler, appears to have blindly accepted the Special Master’s conclusion, finding “no basis” to disturb the conclusion that SILs are irrelevant. This was error.

DoJ’s Ambush – 2 Days Before Trial – Secretly Obtained Complex Reports

On June 7, 2007, at the last moment, just as young little Michelle Cedillo’s US legal counsel were in the very final stages of the long process of preparing for  the full trial, the US Government requested the US Federal Court’s permission to file Dr.  Stephen Bustin’s reports from the English MMR litigation. This was without prior warning at the last moment in a surprise move.

Although Dr. Bustin’s reports were unrelated to Michelle, they were generally critical of the techniques used by the O’Leary lab.

Just two days after the English Court hearing there was an emergency status conference in the US Federal Court on Friday, June 8, 2007.

This was just three days before Michelle’s full trial. Michelle’s US counsel angrily opposed the introduction of the English MMR litigation reports. First, she argued, the reports addressed the reliability of the O’Leary lab, the single-most critical issue in the case. Next, they were filed without notice on the eve of trial. To permit these reports into evidence at that time, counsel argued, would be grossly unfair to Michelle, as her counsel and experts had no time to review them, let alone prepare for cross-examination of Dr. Bustin. These reports, counsel argued, were obtained only through the vastly superior financial resources, and combined efforts, of the US Government and the manufacturers. Worse, counsel argued, they were “cherrypicked” from scores of expert reports filed in the British litigation. Michelle’s counsel requested a continuance. The US Court refused to continue the hearing, permitted the reports to be filed, allowed Dr. Bustin to testify then relied upon his testimony to dismiss her petition.

Getting Bustin’s Reports

The US Government’s lawyers revealed that these confidential reports were obtained [“unsealed”] only after an extraordinary, expensive, several-month covert effort.

The US Government had secretly applied to the English Court over several months for copies of Bustin’s reports without telling Michelle’s lawyers.  This was a legally “dirty” business and legally and procedurally improper.  The US Government should have disclosed what they were proposing to do from the outset.  But had they done so they would not have been able to launch the surprise attack they did.  This is the US Government and what they did in this case stinks.

This covert action came in for direct criticism from the US Federal Appeals Court during oral arguments in the appeal hearing in the US Court of Federal Appeals: Case No. 2010-5004  Cedillo v HHS 10 June 2010 .

The US Government’s surreptitious effort should have been condemned by the prior US Federal Court hearing Michelle’s case.  Instead they were rewarded with a favourable decision in January 2009.

Ironically, the committee of US lawyers representing the US child claimants [the “Petitioners’ Steering Committee”] in the Omnibus Autism Proceedings had asked US Federal Court Special Master Hastings three years earlier to subpoena Bustin I and II reports from Merck, the American MMR vaccine manufacturer defendant in the English High Court cases.  Special Master Hastings denied the request. Michelle had been given time to find her own British counsel to seek to unseal other documents but had been unsuccessful. This did not cure the prejudice. The playing field was not even.

The US Government had unlimited financial resources and the full assistance of attorneys with the Department of Justice who could counsel them to obtain extra territorial documents, the consent of the vaccine manufacturers, and the ability to hire British attorneys to unseal the Bustin reports.

And there was a snowball’s chance in hell of Michelle’s lawyers getting the documents. In a formally delivered judgement the English Judge  refused the US Government’s request on 6th June 2007. But the US Government got the release of Bustin’s second report [“Bustin II”] at the last minute and persuaded the English Judge to change his decision without an appeal.  This was  only made possible because the UK litigation MMR Defendant drug company Merck and its lawyers bent over backwards to help.  Would they have done that for Michelle’s lawyers had they been making the application instead.  Not a chance.

Just after the English Court had given a reasoned judgement refusing release a Merck English lawyer arrived in the English High Court after a crazy dash through London to provide documents it was claimed facilitated the release by the English Court.  What was odd about this was that there was no  witness or affidavit evidence to confirm the claims made in Court on 6th June 2007 by Merck’s lawyer to get the reports released.

The Mystery of Bustin’s Second Report

Was and is Bustin II reliable?  And how did the US Government come to know of its existence?

Bustin first produced a report in the English MMR vaccine injury litigation for Defendant MMR vaccine manufacturer Merck in 2000 [“Bustin I”].

Much later a request was made in April 2004 for Bustin to inspect Unigenetics – the O’Leary lab in Dublin Ireland.  The odd thing about this was that it was made when the UK inflammatory bowel disease/autism cases in the English MMR litigation were over – the UK Government having withdrawn funding to the cases to continue without a “single shot” being “fired”.

So what was the purpose of the April 2004 request?  Was it  forward planning by Merck to obtain evidence for other cases in the USA or other parts of the world?  Or was it for other purposes?  There was no likelihood of data obtained by an inspection of the O’Leary lab ever being used in the English MMR litigation.  So what was the point?

The UK children’s cases never saw the light of day.  There was no public examination of any of the cases or evidence. The UK childrens’ funding for the autism claims had their funding taken away in September 2003. This was confirmed on English High Court judicial review on 27th February 2004 by Judge Nigel Davis.   [Judge Davis is brother of Sir Crispin Davis a main board director of the Defendants in the case GlaxoSmithKline and the CEO of the owners of The Lancet journal which published and then withdrew the Wakefield/Royal Free 1998 paper suggesting the possibility of a link between autism and the MMR vaccine].

The English Court obliged Merck regardless and provided a letter of request to the Irish Court in Dublin for an order permitting Bustin to have access to the O’Leary lab to facilitate the production of Bustin II. It also seems Bustin was allowed access on behalf of Merck by the Irish Court without an expert also appointed to have access on behalf of the claimants.  There was no means of scrutiny of what he did or the report he wrote.

In May 2005 an application was made to the English Court for disclosure of other documents but not Bustin II.  This application was not for the purposes of the English MMR litigation  nor was this application made by the US Government or for the US Federal Court Omnibus Autism Proceedings.  It was for use in the US in the case of Jared Wright and others in May 2005.  So whilst the title of the application to the English court was that of the English MMR litigation case [Sayers et al] the application was not made for any purposes in that case at all.

Bustin II was also never formally filed or lodged with the English Court.  It was never available from the Court for public access or scrutiny.  So when the US Government came to the English Court at the last minute in June 2007, Bustin II and some other expert reports were not disclosable or useable in other proceedings without permission of the English Court.

How Did the US Department of Justice Learn About Bustin II

The US Department of Justice originally knew nothing of the content of Dr Stephen Bustin’s reports.  It seems The Sunday Times’ journalist Brian Deer was routinely colluding with and passing information and documents to the US Department of Justice. This is according to his own admission posted on a well-known web blog leftbrainrightbrain.co.uk and quoted by respected UK journalist and political commentator Melanie Phillips: “A Deer In The Headlights” The Spectator 16th February 2009.

Deer wrote:-

the US government sought my help in mounting its case in Cedillo ….. I assumed that they would have sophisticated contacts …… and could pretty much get what they wanted. However, on a number of occasions I would come home, find an email from the department of justice asking me for a document, and see that the next day it was being run in court. ……. I recall supplying a key document on the O’Leary lab business, which the DoJ didn’t seem to know about just weeks before the hearing. Hence the late surfacing of Bustin and Chadwick. It was me wot done that, and I’m glad.”

So before the US Government came to the English Court it seems someone had provided Sunday Times journalist Brian Deer with a copy of Bustin II prior to June 2007.   If that is the case and if Deer disclosed that document to the US Department of Justice, that was done without sanction from the English Court.  No ordinary member of the public would have known the document existed, nor what it contained nor could they have obtained a copy from any official source without application to the English Court. If what Deer disclosed was Bustin II then that seems to be something which could not be done lawfully.

Is this the reason the US Department of Justice embarked on this surreptitious course of action?  If they disclosed in the US Federal Court  even at this late stage that they were applying for Bustin II and were seeking to introduce it, presumably they would have to have said why.  If the reason was they already had Bustin II [seemingly illegally under English law but presumably not under US law] would they have been required by the US Federal Court to disclose the copy of Bustin II they already had and how they got it?  Would they also then in so doing have revealed the means by which they obtained it was not lawful under the law of another country? [Added 21 June 2010].

Following whatever it was journalist Deer disclosed to the US Government, the US Department of Justice [“DoJ”] representing the Defendant US  Department of Health and Human Services [“US DHHS”] in the US Omnibus Autism Proceedings made the application which was heard in the English High Court on 5th and 6th June 2007 for release of a copy of  Bustin II and some other expert reports.

US Government’s Request Denied By English Court And Suddenly Granted The Same Day

Early in 2007 the US Department of Justice instructed English law firm Nabarros to apply for Bustin II and other documents.  At the hearing in London on 5th June 2007 and to persuade the English High Court to release the UK MMR vaccine injury expert reports of the drug company defendants from Drs. Bustin, Rima, and Simmonds the US Government’s lawyers threatened the English Court that American vaccination rates would fall if Michelle’s claim was not defeated.  [Sayers v. Smithkline Beecham Plc, (2007) EWHC 1346 (QB), 2007 WL 2041770].

This was an odd argument to deploy before the judge concerned. English High Court judge, Judge Keith, was responsible for the case management of the UK MMR vaccine injury litigation cases. Why should the English lawyers have thought such an argument was worth putting to the judge responsible for the UK litigation corresponding to the US case of Michelle Cedillo and 5000 or so other injured US  child litigants. [Added 21 June 2010].

Judge Keith, in his 6th June 2007 judgement dated and issued the same day then agreed release of Bustin II  notwithstanding having stated in his judgement he was clear only a witness statement and summary had been included in the 2005 bundle:-

23. Different considerations apply to Professor Bustin’s second report.  Despite what I thought yesterday, that report was not filed with the court as part of the bundle filed with the court in May 2005 for the use at the hearing of Merck’s application under rule 31.22.  What was included in that bundle was a witness statement from Professor Bustin, summarising the effect of the report.  Since that report has not been filed with the court, it is not a document to which rule 5.4C(2) can apply.  That does not mean that the Secretary for Health can never get access to it.  Merck is prepared to make it available to the Secretary for Health, but in order to do so, Merck has to obtain the court’s permission to do so under rule 31.22.  No such application is currently before the court, but if one was, it is difficult to see how that application could be decided any differently from the Secretary for Health’s present application under rule 5.4C(2).

So the English Court judgement of 6th June 2007 granted consent only for the use of Bustin I and the reports of Professor Simmonds and Professor Rima and strictly only for use in the US Omnibus Autism Proceedings.  But immediately after giving that Judgement with the parties concerned in the application still in Court [other than the UK parents] Merck’s lawyer turned up with documents claiming to facilitate the release by the English Judge.  Michelle’s lawyers were of course not present. Only a handful of the legally unrepresented UK parents were present from the 1600 or so sets of UK parents involved – not having been served with any or proper notice of the US DHHS’ application. [Added 21 June 2010].

Whilst the parties were still in Court before Judge Keith the English solicitors acting for Merck had gone to look for what was claimed to be a duplicate of a hearing bundle used in the May 2005 Jared Wright application and brought it to the court.  This was to substantiate the claim Bustin II was in divider 2 of that bundle.  The bundle was handed to Judge Keith to examine.  No formal witness statement or affidavit was produced to verify the provenance of the bundle of documents concerned.

Clearly, it is unlikely Merck would have gone to this effort for Michelle’s or any other US Claimant child’s lawyers.  The end result of any attempt by the US Claimant children to have obtained Bustin II would have been a certainty of failure.

After getting this information but after already having delivered his judgement Judge Keith stated:-

I am sorry I rather led you up the garden path yesterday.  My recollection was wrong.

….  I will tell you where I got my latest information from.  That was the supplemental bundle that had been filed for the application at the beginning of last month.  That supplemental bundle included the relevant documents which had been included in the May 2005 bundle.  That included the witness statement of Professor Bustin in 2005, but not his November 2000 report.  I was assuming that that meant that the November 2004 report had not been included in the hearing bundle.  If it transpires that it was included in the hearing bundle, then no distinction can be or ought to be drawn between his second report and his first report and the reports of Professor Simmons and Mr Rema.  The question is how one resolves that now.

…. When the judgment has been transcribed, I will make amendments to it to reflect — no, I will only be re-writing history.  The transcript of our discussion post-judgment will reflect the alterations will have been made.

Relaxed Approach of The English Court to Keeping Documents

Unlike the USA where documents are formally filed, docketed and kept for public inspection and copying, the English Court does not apply that level of formality.  Including a document in a bundle produced for a hearing does not mean any copy is ever kept by the Court or that the document is available to anyone.  Document bundles are often handed back to the parties’ respective lawyers at the end of a hearing.  The Court normally does not keep hearing bundles.

Unless directly involved in the litigation ordinary members of the public are unlikely to know what is going on in any English Court case.  Even if they are to know and understand they would have to be closely involved, such as a lawyer managing the case on behalf of a client.

Who Is Dr Stephen Bustin

Stephen Bustin is a Professor at the Institute of Cell and Molecular Science (School of Medicine and Dentistry) at Queen Mary College, University of London.  His claimed areas of expertise are molecular oncology; genetics of colorectal cancer; role of dietary factors in aetiology of colorectal cancer; real-time PCR; real-time RT-PCR.

And Was Bustin II Reliable

It seems not according to the Michelle’s Lawyers in their appeal case.

In his reports, Dr. Bustin stated he had the opportunity to examine a small sampling of the O’Leary lab notebooks — notations totally unrelated to Michelle or any petitioner in the OAP. In this regard, this small sampling formed the basis for the opinions of three British “manufacturers’” experts used by the US Government to attack the O’Leary lab. In sum, the US Federal Court at Michelle’s original hearing allowed highly technical, last-minute evidence, totally unrelated to Michelle, and used it to assist the Special Master of the US Federal Court to dismiss her petition for compensation.

This was despite the fact that the O’Leary lab notebooks claimed to have been reviewed by these experts have never been unsealed in the British litigation and were unavailable for Michelle to inspect.  It in fact seems they were never made available in the UK MMR litigation, let alone filed with the English Court, access having been provided to Stephen Bustin by a Court in a different Country, Eire [Republic of Ireland].

To demonstrate the complexity of this material, Dr. Bustin asked Special Master Hastings at Michelle’s original hearing whether he understood the testimony. Special Master Hastings said “no.” In the end, Dr. Bustin, unwittingly, helped Michelle. He attacked another British expert, Dr. Finbar Cotter, whose report the US Government had neglected to obtain. Dr. Bustin was forced to concede that Dr. Cotter’s lab had replicated the O’Leary lab’s results of samples with substantial inflammation levels (“SILs”).   For good reason, the US Government also “neglected” to obtain the key reports filed by Dr. O’Leary himself or by his molecular biologist, Dr. Shields.

The US Federal Court’s Special Master’s reliance on these materials is even more troubling in light of the ample evidence of the  O’Leary lab’s reliability at the original hearing and in Michelle’s motion for reconsideration and in the absence of any dispute with respect to Michelle [because her biopsy revealed a substantial inflammation level (“SIL”)].

However, in the appeal decision the Appellate Court stated to the contrary that:-

In particular, petitioners describe Dr. Bustin’s and Dr. Rima’s testimony regarding the reliability of the Unigenetics work as equivocal, or as only applying to some of the Unigenetics results, but not all. However, as both the Special Master and the court noted, Dr. Bustin and Dr. Rima clearly testified that their criticisms were not simply limited to certain of Unigenetics’ results and that they found all of the Unigenetics work to be unreliable. Petitioners also urge that a letter written by a Dr. Michael Oldstone, which was filed in Snyder, supports the reliability of the Unigenetics work. To the contrary — Dr. Oldstone’s letter is clear in stating that he could not reliably replicate the Unigenetics results and that the 20 percent error rate he encountered completely undermined his confidence in the testing. It was on this basis that he declined further work with the laboratory. We find that the Special Master considered all of the evidence in context and did not err in concluding that the Unigenetics testing was unreliable. ” [Text added 5 October 2010]

Judge Wheeler had blindly accepted the Special Master’s conclusion that SILs were irrelevant.

To “remedy” this error, at the subsequent hearing of a completely different child’s US Court case [Snyder], the US Government presented the testimony (and reports) of another British manufacturers’ expert, Dr. Bertus Rima.

Although Michelle’s counsel was not present at Snyder, unaware that he would testify against Michelle, and not permitted to cross-examine him, Dr. Rima attempted to rebut this powerful aspect of Michelle’s evidence. Her SIL, he said, was too high. It was implausible, he swore, and could only have resulted from contamination in the O’Leary lab.  Despite the unfairness of this surprise testimony in Snyder, Special Master Hastings relied upon it when he dismissed Michelle’s petition.   Worse, he rejected her petition for reconsideration even when she pointed out to him that Dr. Rima’s opinion was based upon a gross mathematical miscalculation.  For him to do so was error. For Judge Wheeler to have permitted him to do so was error.

Dr Bertus Rima’s Error of Basic Math

Dr. Kennedy demonstrated that, in Snyder, Dr. Rima had made a division error when he testified that Colton Snyder’s copy numbers (i.e. inflammation levels) of 3400 were unbelievably high. When Dr. Rima divided 34,000 by 100, he mistakenly arrived at 3400, when the correct number should have been 340.   When Dr. Kennedy used Dr. Rima’s formula to calculate Michelle’s copy numbers (i.e. inflammation levels), he found the levels to be “very plausible.”   Affirming the Special Master’s decision, Judge Wheeler implied that Michelle waived this argument by failing to bring it to the Special Master’s attention sooner.   This was unfair and unjust.

It was only when Michelle realized the importance that her special master would give this evidence, presented by a different expert, in a case by a different petitioner, heard by a different special master, that she felt the need to respond. In these circumstances  key evidence has been ignored and deference is unwarranted. In any event, Dr. Kennedy’s affidavit remains a part of the record. Special Master Hastings commented upon all of the new evidence submitted by Michelle except Dr. Kennedy’s affidavit! Judge Wheeler’s failure to address this gross omission on the initial appeal was clear error.

What Else Was Done Wrongfully In Michelle’s Case

The US Federal Court Special Master discounted the opinions of Michelle’s treating physicians.

Michelle’s medical records demonstrate that several of her treating physicians associated her illness with her MMR vaccine. These physicians include: (1) Dr. Daniel Crawford, her pediatrician; (2) Dr. William Masland, a neurologist; (3) Dr. Lisa Shigio, an audiologist; (4) Karlsson Roth, a developmental psychologist; (5) Dr. Sudhir Gupta, an immunologist; (6) Dr. Ira Lott, a pediatric neurologist; and (7) Dr. B.J. Freeman, a neuropsychologist.

The special master afforded these records absolutely no probative value. In this regard, Michelle concedes, these doctors did not conclude that her MMR vaccine had caused her autism. However, they should have been afforded significant probative weight that the vaccine likely harmed her. Capizzano, 440 F.3d at 1326. In these circumstances, the special master abused his discretion by affording no weight to the statements of treating physicians in Michelle’s medical records. Judge Wheeler’s blind acceptance of this finding was error.

The special master rejected the opinions of Michelle’s experts who testified that her measles vaccine substantially contributed to her IBD, brain damage, and autism. Instead, he accepted all of the opinions of the US Government’s seventeen (17) experts. Michelle did object to the gross unfairness of permitting the highly prejudicial, last minute, technical materials submitted by Dr. Bustin. However, in the end, the US Government’s expert evidence was largely supportive of Michelle’s (7) Dr. B.J. Freeman, a neuropsychologist. The special master, however, afforded these records absolutely no probative value. In this regard, Michelle concedes, these doctors did not conclude that her MMR vaccine had caused her autism. However, they should have been afforded significant probative weight that the vaccine likely harmed her. Capizzano, 440 F.3d at 1326. In these circumstances, the special master abused his discretion by affording no weight to the statements of treating physicians in Michelle’s medical records. Judge Wheeler’s blind acceptance of this finding was error.

The Special Master ignored concessions of the US Government’s expert witnesses.

In the Vaccine Program a petitioner is required to prove a preponderance of evidence and not a scientific treatise proving to the scientific standard of beyond doubt what caused the injury and exactly by what biological mechanism.  This is in fact no different from standard pharmacology and the assessment of adverse drug reactions.  It is possible to prove to with high certainty that a drug has caused an adverse reaction without carrying out scientific experiments or proving the exact causal mechanism.  So the standard of proof in this special US Federal Court is little or no different to that applied by drug regulators and in standard pharmacology.

The US Government experts conceded important aspects of Michelle’s case.

The special master, however, relied solely upon the number of the US Government’s experts, their obvious qualifications, and their conclusions to find against Michelle.  However, in so doing, the special master chose to ignore the many concessions of the US Government’s experts that supported Michelle’s case.

Oddly the special master found the US Government’s experts’ conclusions reliable, but their concessions unreliable. This was legally in error.

For Judge Wheeler on the initial appeal to have permitted this grossly selective consideration of the record was also error.

Dr. Jeffrey Brent’s Concessions

Immune dysfunction must be present to permit a measles infection to persist. That fact was not in dispute. Michelle presented evidence that, in her case, mercury containing vaccines [“TCVs”] likely caused the initial damage to her immune system which allowed measles to persist in her gut long after it should have been eliminated from her body.

The special master rejected this. He found no evidence that TCVs can harm the immune system. However, to do so, the special master was required to ignore all evidence that contradicted this conclusion. This included that provided by the US Government’s expert toxicologist.

Dr. Brent conceded

  • a large body of literature exists concerning the adverse effects of mercury on the immune system;
  • the effect of organic mercury (contained in TCVs) on the immune system is five times more potent than inorganic mercury;
  • “mercury containing compounds are immunomodulatory” and toxic at very low exposure levels to T-cells;
  • exposures to low concentrations of heavy metals, including mercury, causes “silent” clinical symptoms which upon long term follow-up reveals “clear evidence of tissue or organ dysfunction”;
  • low doses of mercury can have an inhibitory effect on human T-cells.

It was error for the special master to ignore these concessions and the supporting literature. The special master dismissed the Goth study for being an invitro study that studied Thimerosal, not ethyl mercury (again, Thimerosal is approximately 50% ethyl mercury).  He criticized the Agrawal study. While an in vivo study, this study was deficient since it too studied Thimerosal.  He ignored the entire body of literature that Dr. Brent conceded showed ethyl mercury has a detrimental effect on all elements of the immune system.

It was error for the special master to ignore the vast body of evidence regarding the effects of mercury on the immune system, and then declare that Michelle had failed to prove that mercury exposure can lead to a dysfunctional immune system. In any event, it is not necessary for Michelle to prove that TCVs damaged her immune system. It is only necessary for her to show that a dysfunctional immune system, for any reason, allowed the vaccine-strain measles virus to harm her.

Dr. Stephen Hanauer’s Concessions

Michelle alleges that the persisting vaccine-strain measles virus from her MMR caused her to suffer IBD. The special master, however, determined that she does not suffer IBD. Dr. Hanauer, however, the US Government’s expert gastroenterologist, provided significant support for Michelle’s argument. While denying that Michelle has IBD, he reluctantly conceded that she has significant bowel symptoms.

He also agreed she has aphthous ulcers, which can evolve into IBD, specifically Crohn’s disease, and that the ulcers are often the first sign of Crohn’s disease. He agreed that Michelle has elevated OmpC and that OmpC is elevated in 60% of Crohn’s patients. He agreed that diarrhea frequently occurs after measles vaccine. He agreed that Michelle’s lower abdominal symptoms persisted after her measles vaccine. He agreed that both genes and environmental triggers cause IBD, a chronic condition.

He conceded that a virus can trigger a chronic inflammatory response.

He conceded that Michelle suffers from arthritis and eye problems, both of which, he agreed, are associated with IBD.  He conceded that Michelle’s present gastroenterologist, Dr. Ziring, treats Michelle with Humira, a medication used for IBD.

In light of these concessions, as well as the opinions of Michelle’s present treating gastroenterologist that she has IBD, the special master’s finding was in error and unlawful.

Dr. Diane Griffin’s Concessions

Dr. Griffin, an immunologist and virologist, conceded:

  • measles is one of the most infectious of all viral diseases;
  • a “target organ” of the measles virus is the gastrointestinal tract;
  • the attenuated measles vaccine can cause progressive, fatal respiratory disease or neurological disease in immunocompromised individuals;
  • measles virus affects many components of the immune system;
  • measles virus causes immunosuppression for months after the period of viremia;
  • measles virus skews T cells, and that when Th1 and Th2 are not in balance the body’s ability to clear viruses will be impaired;
  • the measles vaccine, like the wild virus, causes lymphopenia;
  • “you can definitely identify changes [in antibodies] that are occurring as part of the induction of the immune response to the vaccine”;
  • Michelle’s first fever after the MMR vaccine was related to the MMR vaccine;
  • measles can cause neurologic disease;
  • the risk of viral persistence increases in an immunosuppressed person;
  • viruses can persist in the human body;
  • in her own study, she found the presence of a virus’ RNA indicated that “viral protein may continue to be made, providing the impetus for the continued presence of [virus]-specific B cells in the brain.”

Dr. Griffin agreed that the PCR technique used by the O’Leary lab is commonly used to detect viral RNA.

She agreed she has used the PCR technique and detected measles RNA in the blood of immunodeficient children long after exposure to the virus. Indeed, she wrote:

we believe the presence of measles virus RNA represents continued measles virus replication, not simply the persistence of measles virus RNA after cessation of viral replication. This is supported by detection of measles virus RNA from multiple clinical sites.

Dr. Griffin agreed that a measles vaccine should not be given to an immunosuppressed child and agreed that if Michelle had evidence of a persisting, replicating measles virus, it would be “an important observation” and “should definitely be followed up” by a physician.

Dr. Brian Ward’s Concessions

Dr. Ward agreed that

  • wild measles virus causes a skewing towards a Th2 response, which happens to occur during the period of maximum viremia (1-2 weeks after exposure or immunization);
  • this skewing of the Th2 response causes immunosuppression and allows the development of opportunistic infections;
  • measles vaccine can cause a skewing towards a Th2 response, like wild type measles can;
  • measles virus can persist;
  • “‘[t]he type of diseases that persisting viruses cause are often novel and unexpected’”;
  • “‘[t]he result is a disturbance in the host’s biologic equilibrium. That’s one important direct effect of persistent virus replication is to disorder the normal homeostasis of the host and thereby cause disease without destroying the infected cell.’”

Dr. Ward when confronted with Dr. Oldstone’s statement that an important direct effect of persistent virus replication might be a “‘virally caused neurotransmitter defect of neurons altering cognitive learning and yielding behavioral disorders.’” said he is not an autism expert, but agreed that it would “describe some of the children with ASD.”

Dr. Robert Fujinami’s Concessions

Dr. Fujinami failed to appear at the hearing, but provided significant evidence for example, that measles virus can persist in human cells, injure tissues, and cause a potentially damaging autoimmune response.

The US Government’s Experts’ Concessions On the O’Leary Lab

Dr. Bustin’s testimony supported the reliability of the O’Leary lab for Michelle’s test result. At the hearing, he attempted to show that another laboratory (Dr. Finbar Cotter) in London was unable to replicate the O’Leary lab’s results (i.e. detecting measles RNA in samples) using the O’Leary techniques. However, as Dr. Bustin’s power point presentation showed, Dr. Cotter’s lab was able to replicate the O’Leary results using the O’Leary techniques for test results with SILs.

Although this critical fact was discounted by the special master and Judge Wheeler, it remains in the record that Dr. Bustin agreed that his dispute was only with the O’Leary lab’s MILs and he did not deny that Michelle had SILs.

In the US Snyder case the US Government  introduced a letter from Dr. Michael Oldstone. 88 Fed.Cl. at 731. In his letter, Dr. Oldstone revealed “[i]n the early 2000s” he reviewed the O’Leary lab’s protocols for detecting measles virus with PCR, and found them “to be sound.”  In addition, Dr. Oldstone stated, Dr. O’Leary’s test results agreed with his own in 80% of the samples he sent to the O’Leary lab.  Dr. Oldstone also indicated that there was concordance between the two laboratories with respect to SILs.  Thus, there was concordance among three separate laboratories for test results for patients with SILs. The only disputes concerned the results with MILs.

The special master used Dr. Rima’s testimony in Snyder against Michelle to reject this argument. In Snyder, Dr. Rima testified that the O’Leary lab’s SILs for Colten Snyder were “[t]oo high to be believed.”   Unable to cross-examine Dr. Rima in Snyder, Michelle filed the affidavit of Dr. Ronald Kennedy, who explains that Dr. Rima’s opinions in Snyder with respect to SILs were based upon a gross mathematical computation error.  Dr. Kennedy then uses Dr. Rima’s properly corrected formula to calculate Michelle’s SIL, and concludes that her SIL, like that of Colten Snyder, was “very plausible.”

Michelle also relied on portions of the testimony of the US Government’s expert Dr. Rima, who conceded that the O’Leary lab used allelic discrimination to attempt to distinguish between vaccine-strain and wild measles viruses. Snyder, 2009 WL 332044 at 125.

Dr. Rima also agreed:

  • if measles virus RNA is present, the virus may be replicating;
  • the Uhlmann paper indicated that the O’Leary lab had detected measles protein using immunohistochemistry;
  • the US Government’s expert Dr. Griffin, in her 2001 paper, using PCR technology, found positive measles RNA in samples of immunosuppressed children taken 60-90 days after exposure to the measles virus.

The special master’s refusal to consider this evidence was error.

The Special Master ignored evidence of allelic discrimination

The process of “allelic discrimination” is the method used by scientists to determine whether a virus in question is of wild origin or of vaccine-strain origin.

The special master determined that Michelle had failed to prove that Michelle’s measles virus RNA, if detected at all, was vaccine-strain measles virus.  However, in making this finding, the special master ignored the absence of evidence that Michelle was ever exposed to a wild measles virus. He also discounted Michelle’s direct evidence that the O’Leary lab had used allelic discrimination and that the RNA recovered was vaccine-strain measles virus.

Michelle’s medical records indicate that she has never been exposed to wild measles.

In addition, the O’Leary lab’s method used to distinguish between wild type and vaccine strain measles, an accepted methodology, was not challenged by any of the US Government’s experts.

The special master’s refusal to consider this evidence was error.

The Special Master refused to consider evidence concerning persistent measles virus and replication

Dr. Griffin, the US Government’s expert virologist, discounted the results of Michelle’s gut biopsy that the presence of a significant amount of measles virus RNA in her gut tissue. She indicated that the presence of measles virus RNA was not indicative of disease because protein was required for the virus to replicate.

During cross-examination, however, she acknowledged that she had not reviewed the Uhlmann article that formed the basis for Michelle’s contentions that the O’Leary laboratory engaged in good and accepted practices.

Dr. Griffin was thus unaware that the O’Leary laboratory had found protein via the process of immunohistochemistry and that the Uhlmann article reflected that finding.

In any event, once again, Dr. Griffin, herself, had found replication of measles virus, in the absence of protein, in one of her publications.  In this article, Dr. Griffin was able to recover measles RNA from the blood, urine and trachea of HIV positive patients 30 – 60 days post-immunization. In her article, she declared that recovery of measles RNA from multiple sites from different patients was indicative that measles virus was persistent and replicating. The special master, however, ignored this evidence.

Thus, the special master ignored multiple sources of information that supported Michelle’s medical theory that the measles RNA found in her gut tissue was not inert, but multiplying in her gut tissue and causing harm to her gut and her brain. The special master’s refusal to consider this evidence was error.

The Special Master rejected the opinions of Dr. Krigsman

The special Master accepted the testimony of the US Government’s expert, Dr. Hanauer, who has never seen Michelle, that she does not have IBD. In so doing, he rejected the testimony of Michelle’s treating gastroenterologist, Dr. Arthur Krigsman. Indeed, special master reserved special venom for Dr. Krigsman, a board-certified gastroenterologist, accusing him of “gross medical misjudgment.”

In fact, the special master’s attack is grossly unfounded.  The special master relied heavily upon the disciplinary action instituted by Lenox Hill against Dr. Krigsman for attacking his credibility. What he failed to relate was that the hospital, in violation of its own medical staff by-laws, attempted to curtail Dr. Krigsman’s privileges, without due process, to prevent him from conducting further colonoscopies of autistic children. The hospital paid damages, and the parties went their separate ways. The “Texas matter,” as the special master noted, involved an administrative error, and the “Florida proceeding” involved a failure to fulfill a special continuing education requirement of the Florida Board. None of these proceedings concerned the competence of Dr. Krigsman as a physician or gastroenterologist.

In response, Michelle points out, at the time of her hearing, Dr. Krigsman had evaluated the gastrointestinal tracts of a thousand autistic children.

He testified:

  • about his initial skepticism that autistic children had significantly more bowel symptoms than nonautistics;
  • that he conducted a history and physical of the initial eight (8) autistic patients referred to him, and when appropriate, ordered non-invasive testing; when testing revealed no abnormalities, he declined to treat them further;
  • only when shown an article by the author of a medical school textbook did Dr. Krigsman reconsider his original thinking.

He offered to conduct additional evaluations of the original patients and all parents agreed. See generally. The special master failed to acknowledge that most parents will not allow a physician to conduct invasive procedures on their child unless the symptoms are chronic and unremitting, cause physical and emotional distress to their child, and the child has been non-responsive to traditional treatment. All eight of Dr. Krigsman’s original patients ultimately underwent  colonoscopies.

In all eight patients, he saw similar findings as were described in the article.

The special master also ignored the fact that Theresa Cedillo, Michelle’s mother, only sought Dr. Krigsman’s help after Michelle’s treating gastroenterologist refused to transfer her to the hospital where he practiced, despite the fact that she was dehydrated and had lost approximately 20 pounds.  He ignored the fact that Dr.  Krigsman obtained a proper history, conducted a proper physical exam, ordered appropriate testing and only after doing so arrived at a diagnosis.

He ignored Dr. Krigsman’s testimony that the diagnosis of Michelle’s IBD was based on all the evidence available to him, evidence that included Michelle’s history, her physical examination, results of diagnostic testing that included positive serological marker for IBD (+ Omp-C), elevated inflammatory markers (C-reactive protein (“CRP”)) and the presence of aphthous ulcers (pre-Crohn’s lesion). Further, the special master ignored the fact that Michelle had both uveitis and arthritis, commonly associated disorders of IBD. The special master especially ignored the fact that Michelle had responded to treatment with Remicade, an anti-inflammatory agent used for the treatment of IBD. Even worse, he ignored the findings of Michelle’s current treating gastroenterologist, Dr. David Ziring, who had no doubt that Michelle had inflammatory bowel disease  and who ordered Humira for it, specifically noting on the prescription that it was for “Crohn’s Disease.” The records of Dr. Ziring, Michelle’s current treating gastroenterologist, were not available at the time of hearing and were filed in support of a motion for reconsideration, which was denied by the special master.

The special master also ignored evidence of the consensus statement formulated by a renowned body of specialists in autism and pediatric gastroenterology convened by Autism Speaks on the “appropriate diagnostic evaluation and treatment of GI symptoms in children with ASD [autistic spectrum disorder].”

He ignored the fact that Dr. Krigsman was an invited participant, and that the evaluation that was subsequently deemed proper and appropriate, mirrored the evaluation he had provided for Michelle.  Instead, the special master credited the testimony of Dr. Hanauer, the government’s paid witness, an adult  gastroenterologist who does not evaluate pediatric patients, who has never looked at the gastrointestinal tract of an autistic child, and who has never examined Michelle.

Dr. Hanauer’s conclusion that Michelle does not have IBD is based on only one fact — that inflammation was not found in Michelle’s pathology slides.  He asserted that IBD could not be diagnosed in its absence.  What both Dr. Hanauer and the special master refused to acknowledge was that the successful treatment noted in Michelle after she began Remicade, was likely responsible for the lack of inflammation noted on the pathology slides. While the special master can be excused for this oversight, Dr. Hanauer does not enjoy that deference.

The special master’s refusal to consider this evidence was error.

The Special Master refused to consider evidence of neuroinflammation

Tthe US Government’s experts did not deny “that inflammation may be present in the brains of autistic persons, and may possibly play a causal role in autism.”  The special master conceded as much.  He asserts, however, that Michelle failed to establish that measles caused her to suffer persistent neuroinflammation. Once again, the special master ignored relevant evidence to arrive at this conclusion.

First, it is undisputed that persistent wild measles infection has resulted in two recognized brain disorders, subacute sclerosing panencephalitis (“SSPE”) and measles inclusion body encephalitis (“MIBE”), and that both disorders involve neuroinflammation. It also is undisputed that both disorders have a prolonged latency period after exposure before the onset of symptoms. The special master failed to acknowledge, however, that vaccine-strain measles, was recovered from the brain of one child with MIBE. Clearly, then, if wild type measles can cause a latent inflammation of the brain, it is reasonable to believe that the attenuated measles vaccine, which is simply a weakened version of the live measles virus, can also cause a latent infection of the brain.

In addition, as the special master was well aware, if encephalitis occurs in a child 5-15 days after measles immunization, it constitutes a Table injury and it is presumed that the vaccine is the cause of the encephalitis. § 14. Encephalitis is an inflammation of the brain. Thus, it is difficult to fathom why the special master ruled that it is unproven that measles vaccine can cause neuroinflammation.  Michelle was unable to present direct evidence of neuroinflammation. No autopsy can be performed as she is still alive.

Michelle’s “Motion for Reconsideration” included several chapters from a text edited by Dr. Andrew Zimmerman, one of respondent’s expert pediatric neurologists, who the US Government declined to call at hearing. They support Michelle’s theory that autism is caused by neuroinflammation. The special master ignored them.

He also ignored the findings of Dr. Oldstone who has spent his career studying persistent viral infections. For him to have ignored this evidence was error.

The Special Master ignored evidence concerning Michelle’s immune dysfunction

The special master discounted the testimony of Dr. Vera Byers.

Dr. Byers testified that Michelle “has an unusually low CD8 count, and as a result she has an elevated CD4:CD8 ratio. An elevated CD4:CD8 ratio is compatible with autoimmune disease.”  In addition, Dr. Byers stated, Michelle had an elevated CD 20. In this regard, she testified, the significance of an elevated CD 20 is that, “you’ve got abnormally elevated B cell precursors, and it could go along with the abnormally elevated IgG2 and IgG4. . . .The fact that she has abnormally elevated IgG2 and IgG4. . .is consistent with TH1/TH2 skewing.”

At the hearing, referring to the laboratory findings of one of Michelle’s treating physicians, Dr.  Gupta, the US Government’s expert Dr. Ward, once again,  acknowledged that TH2 skewing causes immunosuppression.  In a letter to Michelle’s parents, Theresa and Michael Cedillo, Dr. Gupta wrote, “the immunology testing. . .shows that Michelle has almost normal immune functions.”  In the same letter, Dr. Gupta advised Michelle’s parents that she qualified for “a medical exception to the vaccination requirements of the school system.”

Incomprehensibly, the special master accepted the testimony of the US Government’s expert, Dr. McCusker, who constructing her own chart from different sources, then concluded that Michelle’s immune system was normal. The  record clearly indicates that Michelle’s immune system was damaged. Dr. Zimmerman’s text, significantly, includes a chapter by Dr. Paul Ashwood, who discusses immune abnormalities in autistic children.   Michelle suffered from several of the abnormalities listed by Dr. Ashwood and Michelle relies upon Dr. Ashwood to support her theory that she suffers from immune dysfunction. Further, the special master ignored evidence submitted by the US Government’s expert, Dr. Fujinami that some autistics, as does Michelle, suffer from a Th2 skewing of the adaptive immune system, that affects a person’s ability to eliminate viruses from the body.

The Special Master refused to consider significant post-hearing evidence

This was an aspect the US Court of Federal Appeals stated it found troubling in the recent 10th June oral appeal hearing.

Michelle asked the special master to reconsider his decision of February 12, 2009 dismissing her petition. On March 16, 2009, the special master denied Michelle’s Motion for Reconsideration as both untimely filed and without “a good reason” for reconsideration.

The Motion for Reconsideration was filed in light of new evidence not available at the time of the hearing in June of 2007. This evidence, Michelle stated, is based upon the research of leading scientists in the field of autism, including the US  Government’s expert pediatric neurologist, Dr. Andrew Zimmerman. In sharp contrast to critical findings by the special master, this evidence demonstrates that:

  • Postnatal environmental triggers may impact the immune system during the development of the brain, disrupt the normal development of the brain, and cause autism.
  • Regressive autism is not purely genetic and may be caused by postnatal environmental factors.
  • Scientists now accept the concept of gastrointestinal inflammation in autistic children.
  • There is a strong relationship between the immune system, gastrointestinal disorders, and autism.
  • Michelle has inflammatory bowel disease.
  • The O’Leary lab’s primers are reliable in detecting measles RNA
  • Dr. Bertus Rima’s testimony in Snyder, a critical factor in the special master’s rejection of Michelle’s O’Leary lab result, was based upon a gross mathematical error.

In light of the significance of the evidence and the impact of the decision upon thousands of autistic children the Special Master’s failure to reconsider was an abuse of his discretion. Once again, the special master did not strike this evidence and it remains part of the record in this case.

The Special Master’s Decision Was Unlawful

Has Michelle satisfied the burden of proof?

She has a medical theory. Her evidence is overwhelming that the MMR vaccine is capable of causing a wide variety of brain injuries, including autism. Next, there was a logical sequence of cause and effect between her MMR vaccine and her injury. She was healthy, received a MMR vaccine, and as her several treating  physicians attest, she was never again the same. There is no question that her symptoms first occurred within an appropriate time after her MMR vaccine. This fact is supported by Michelle’s medical records and by the US Government’s expert Dr. Griffin. It is even supported by the Vaccine Injury Table that lists “5-15” days after the MMR vaccine as the appropriate time frame for the onset of symptoms of brain damage.

Having presented such a case the burden of proof shifts and the government must prove that the “‘injury. . . described in the petition is due to factors unrelated to the. . .vaccine.’ 42 U.S.C. § 300aa-13(a)(1)(B).” Knudsen by Knudsen v. Sec’y of HHS, 35 F.3d 545, 547 (Fed. Cir. 1994).

She offered expert opinions supported by scientific literature. the US Government offered no evidence of an alternate cause of Michelle’s injuries.

Michelle clearly had a plausible medical theory supported by substantial circumstantial evidence as to how the MMR caused her gut and brain injuries. The records of several treating physicians support a “logical sequence” between the MMR and her injuries, an appropriate temporal relationship, and the absence of an alternative cause.

When Michelle became the first autism “test case,” however, everything changed:

  • Due process was suspended.
  • Now, she had to convince not one, but three special masters.
  • Phalanxes of experts were pitted against her, not just Dr. Wiznitzer.
  • The Federal Court Special Master allowed the US Government to present surprise evidence from England on the eve of trial, use a host of experts provided by the pharmaceutical industry, and even present expert testimony against her in another trial.
  • The US Court refused to accept any aspect of her evidence, even the major concessions made by the US Government’s experts.
  • The special master, and Judge Wheeler, even refused to accept the fact that Dr. Rima’s critical testimony was based on a mathematical error.

Michelle fully appreciates the emotions surrounding her case. She also appreciates the importance of vaccines. However, Michelle submits, she must not be penalized for choosing this unpopular route. She is entitled to compensation based on the evidence in accordance with the statute.

At this time, approximately 5,000 autistic children in the OAP claim vaccines harmed them. There is a $3.1 billion fund available to compensate appropriate cases. An adverse finding in her case, Michelle submits, will drive many of these autistic children into the civil arena. This Court cannot permit this to happen. Certainly, this is not what congress intended.

It is essential that the Vaccine Program, rather than crippling civil litigation, resolve Michelle’s case as well as those of all autistic children in OAP. Persons fairly compensated in the Vaccine Program will not sue manufacturers. How can these persons be kept in the Vaccine Program? The answer is simple. An evidentiary standard that promotes congressional intent must be employed. The Vaccine Act, as interpreted by Althen and Capizzano, provides such a standard.

Fundamental fairness, not hysteria, must prevail.

Wakefield’s Lancet Paper Vindicated – [Yet Again]

[STOP PRESS: New papers keep emerging – see additions below 22nd May & 5th June 2010]

New independent research presented at the 2010 Pediatric Academic Societies Annual Meeting in Vancouver, Canada confirms unequivocally the findings of Dr Andrew Wakefield’s 1998 Lancet paper of an association between autism and serious gastrointestinal disease in children [Full Details Below].

And do vaccines cause autistic conditions?  If you read nothing else we strongly recommend you read this PDF Download:– Text of email from US HRSA to Sharyl Attkisson of CBS News].  In it the US Health Resources Services Administration [HRSA] state to CBS News reporter Sharyl Attkisson

We have compensated cases in which children exhibited an encephalopathy, or general brain disease. Encephalopathy may be accompanied by a medical progression of an array of symptoms including autistic behavior, autism, or seizures.

Despite all the lies and deceit by health official worldwide, the question was answered when the Hannah  Poling story broke in the USA [see CHS article here].  Hannah developed an autistic condition after 9 vaccines administered the same day.  Under the media spotlight the question was answered by numerous US health officials and agencies and broadcast on nationwide TV news from CBS and CNN.  The answer is “Yes”. Full details with links to the original sources can be found in this CHS article: Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines. [Blue Text added 10 April 2011]

The new study was conducted by the Autism Speaks Autism Treatment Network and covered data from 15 treatment and research centers in the United States and Canada.  Of 1185 children aged 2 to18 years with an autistic condition 45% were reported to have GI symptoms. Abdominal pain was most common (59%) followed by constipation (51%), diarrhea (43%), other (40%), nausea (31%) and bloating (26%). Reports of GI symptoms increased with age.  Sleep problems occurred in 70% of children with than those without GI symptoms (30%).  The problems affected all children regardless of gender, ethnic background or intelligence.

Wakefield’s 1998 Lancet case series on 12 children stated:

Interpretation: We identified associated gastrointestinal disease and developmental regression in a group of previously normal children, which was generally associated in time with possible environmental triggers.”

A J Wakefield, S H Murch, A Anthony, J Linnell, D M Casson, M Malik, M Berelowitz, A P Dhillon, M A Thomson, P Harvey, A Valentine, S E Davies, J A Walker-Smith “Ileal-lymphoid-nodular hyperplasia, non-specific colitis, and pervasive developmental disorder in children” THE LANCET • Vol 351 • February 28, 1998. The Lancet paper was retracted by The Lancet after the General Medical Council decision in January 2010 in the case of Professors Walker-Smith, Simon Murch and Mr Andrew Wakefield.  [Added 26 May 2010].

But this is not the first time Wakefield’s research has been confirmed by independent researchers around the world.  Read a previous article and see the list of papers replicating Wakefield’s Lancet paper research: Sunday Times’ Discredited – Wakefield’s Autism Research Verified

And another recently published paper in Pediatrics Journal by 27 authors confirms a medical consensus that

Gastrointestinal disorders and associated symptoms are commonly reported in individuals with ASDs, but key issues such as the prevalence and best treatment of these conditions are incompletely understood.”

Evaluation, Diagnosis, and Treatment of Gastrointestinal Disorders in Individuals With ASDs:PEDIATRICS Volume 125, Supplement 1, January 2010 [Added 22 May 2010].

And yet another just published paper [3 June 2010] from researchers at Imperial College, London also supports Wakefield and Walker-Smith’s original finding.

People with autism are also known to suffer from gastrointestinal disorders and they have a different makeup of bacteria in their guts from non-autistic people. Today’s research shows that it is possible to distinguish between autistic and non-autistic children by looking at the by-products of gut bacteria and the body’s metabolic processes in the children’s urine. The exact biological significance of gastrointestinal disorders in the development of autism is unknown

Children with autism have a different chemical fingerprint in their urine than non-autistic children, Imperial College News Release Thursday 3 June 2010, “Urinary Metabolic Phenotyping Differentiates Children with Autism from Their Unaffected Siblings and Age-Matched Controls,” Journal of Proteome Research, published in print 4 June 2010. [Added 5 June 2010]

Additionally, one of the witnesses in the GMC proceedings against Dr Wakefield writing to the British Medical Journal confirmed the validity of the histopathology on which the paper was based and illustrated how Sunday Times journalist Brian Deer had misrepresented her evidence.  Dr Susan E Davies, Consultant Histopathologist, Addenbrooke’s Hospital, Cambridge stated in the British Medical Journal regarding a BMJ article by Brian Deer that:

There is some misrepresentation …. and lack of understanding of the process in studies involving histopathology.” and that there were significant findings “While a clinical gastroenterologist might consider caecal active inflammation with incipient crypt abscess formation to be normal in children (1), this is a significant finding to be recorded by pathologists

Caution in assessing histopathological opinions.” BMJ Rapid Responses 30 April 2010.

So will Dr Richard Horton, editor of The Lancet now “unretract” The Lancet paper?

Read the abstract of the new US research vindicating Wakefield’s work here:

[2320.7] GI Symptoms in Autism Spectrum Disorders (ASD): An Autism Treatment Network Study

Kent Williams, George J. Fuchs, Glenn Furuta, Margaret Marcon, Daniel L. Coury, Autism Treatment Network GI Committee. Vanderbilt University, Nashville, TN; University of Arkansas for Medical Sciences, Little Rock, AK; University of Colorado at Denver, Denver, CO; Hospital for Sick Children, Toronto, Canada; Nationwide Children’s Hospital, Columbus, OH.

BACKGROUND: The prevalence of GI symptoms in children and adolescents with ASD is uncertain, with studies reporting conflicting results.

OBJECTIVE: To determine the frequency of GI symptoms as reported by parents in a large ASD registry, and to identify factors associated with GI symptoms in children with ASD.

DESIGN/METHODS: Autism Treatment Network Registry enrolled 1420 children, age 2-18 years, with an ADOS-confirmed ASD diagnosis (autism, Asperger disorder, or PDD-NOS) at 15 sites in the US and Canada. Parents completed a GI symptom inventory tailored to the needs of nonverbal children, as well as Child Behavior Checklist (CBCL), Child Sleep Health Questionnaire (CSHQ) and Pediatric Quality of Life (PedsQL) at time of enrollment.

RESULTS: GI symptom data were available for 1185 children. Overall 45% of children were reported to have GI symptoms at time of enrollment. Of GI complaints that occurred within the 3 months prior to enrollment, abdominal pain was most common (59%) followed by constipation (51%), diarrhea (43%), other (40%), nausea (31%) and bloating (26%). Reports of GI symptoms increased with age, ranging from 39% in those under 5 years to 51% in those 7 years and older (p<0.0001). Children ages 1 to 5 years with GI symptoms had higher CBCL t-scores for total problems and for the emotionally reactive, anxious/depressed, somatic complaints, sleep problems, internalizing problems, affective problems, and anxiety problems subscales, all p<0.05. Children ages 6 to 18 years with GI symptoms had higher CBCL t-scores for total problems and for all subscales (p<0.01). Sleep problems occurred more frequently in children with than those without GI symptoms (70% versus 30%, p<0.0001). Children with GI symptoms had lower PedsQL scores (overall score and all five subscales, p<0.01) compared to children without GI problems. Presence of GI problems did not differ by gender, ASD subtype, race, or IQ.

CONCLUSIONS: Parents of children with ASD report a high prevalence of GI symptoms in their children. This prevalence increases with age. GI complaints are significantly associated with behavioral abnormalities in all age groups. GI symptoms are also significantly associated with sleep disturbances and decreased health-related quality of life. Further definition is needed on the role and potential impact of treatment of GI disorders on behavior, sleep disturbance, and quality of life in children with ASD.

Date: Sunday, May 2, 2010
Poster Symposium Session: Autism (10:15 AM – 12:15 PM)
Presentation Time: 10:15 AM
Room: East Ballroom C – Vancouver Convention Centre
Board Number: 7
Course Number: 2320

“Don’t give children flu jab” says chief medical officer

Australia’s chief medical officer Jim Bishop today said health professionals should immediately stop immunising children under five years old with the flu vaccine.  Professor Bishop is concerned about a spike in the number of West Australian youngsters experiencing fever and convulsions after getting the shot: “Don’t give children flu jab: chief medical officer”  Syndey Morning Herald April 23, 2010

This is a precautionary measure while the matter is being urgently investigated by health experts and the Therapeutic Goods Administration,” he said.

The news has been widely reported in the Australian media and now in the UK:  “Dozens of Australian children fall ill from flu vaccine” The Telegraph – Bonnie Malkin in Sydney 23 Apr 2010

Doctors across Australia have been ordered to stop giving young children the seasonal flu vaccine after 44 children fell ill hours after being immunised.”

The question for the UK, USA, Australia and New Zealand is, when are the politicians going to stop corruption in politics and start protecting their voters’ children from corrupt marketing practices in the pharmaceutical industry and clear out from their national Health Departments and Agencies any corrupt and/or incompetent officials and any with unhealthy ties to the drug industry.

Here are links to some of the news stories from the USA, Australia, New Zealand and the UK:

Flu jab scare sparks call for surveillance system – ABC Online

Dozens of children have suffered serious adverse reactions after receiving the flu vaccine in WA. (AFP: Jewel Samad) The number of children suffering

Fevers in 60 children linked to flu vaccine – Sydney Morning Herald

More than 60 West Australian children may have had adverse reactions to the flu vaccine, the state’s health department says. West Australian Health Minister

Dozens of Australian children fall ill from flu vaccine – Telegraph.co.uk – Bonnie Malkin – ‎

Doctors across Australia have been ordered to stop giving young children the seasonal flu vaccine after 44 children fell ill hours after being immunised.

Australia Tells Doctors to Stop Flu Shot for Children – BusinessWeek – Marion Rae

April 23 (Bloomberg) — Australia’s government said children aged five years and younger shouldn’t be given CSL Ltd.’s seasonal flu vaccine

Don’t give children flu jab: chief medical officer – Sydney Morning Herald

Drug regulators are urgently investigating whether the seasonal flu vaccine is safe for children, after the nation’s top doctor said they shouldn’t receive

Ministry warns over flu vaccine – TVNZ

The Ministry of Health is warning doctors not to give a particular type of flu vaccine to children under 5, after reports of children suffering convulsions

Fluvax flu vaccine warning after child convulsions – Stuff.co.nz‎

Doctors have been warned not to use popular flu vaccine Fluvax on preschoolers after reports of children convulsing. The Health Ministry said it had

Children’s flu vaccine suspended – ABC Online

SHANE MCLEOD: The country’s chief medical officer has suspended the flu vaccine for children under five. The decision comes after 23 children in Perth

Probe on flu shots after kids fall ill – Herald Sun

DRUG regulators are urgently investigating whether the seasonal flu vaccine is safe for children, after the nation’s top doctor said they

Health scare halts flu vaccine for kids – The Australian

DOCTORS have been told to stop giving the seasonal flu vaccine to children under five amid a serious health scare in Western Australia.

Children sick after flu jab – ABC Online

Dozens of children have suffered serious adverse reactions after receiving the flu vaccine in WA. The Health Department has suspended the free flu

Flu jabs suspended in WA – Sydney Morning Herald

The West Australian government has temporarily suspended its free flu vaccination program for children under five after some youngsters developed high

Flu shots suspended after kids hospitalised – ABC Online‎

The Western Australian Government has suspended all flu vaccinations for children under five while it investigates a spike in admissions to Princess

Doctors: Stop flu vaccine for children – Daily Telegraph

Australia’s chief medical officer has told doctors to stop giving the seasonal flu vaccine to children. DOCTORS have been told to stop giving NSW children

NZ children suffer serious reactions to flu vaccine – Radio New Zealand

Some New Zealand children have suffered serious adverse reactions as a result of receiving the seasonal flu vaccine. The Government of Western Australia on

Stop kids’ flu vaccine – Pharmacy News

Australia’s chief medical officer has told all GPs and immunisation providers to stop giving seasonal flu vaccine to children under five years due to a

Flu vaccine ban for children under 5 after kids fall ill in Perth – Courier Mail‎

Australia’s chief medical officer has told doctors to stop giving the seasonal flu vaccine to children. AUSTRALIAN health authorities have announced a

Child flu shots suspended in West Australia – Radio New Zealand‎

Western Australia has suspended free flu vaccinations for children under five, after at least one became seriously ill and dozens suffered serious adverse

No flu shots for kids in WA – Ninemsn

The Western Australian government has put a halt on all flu shots for young children, after reports of many suffering adverse side effects.

Flu vaccine linked to convulsions – Otago Daily Times‎

Doctors in New Zealand have been advised against using the influenza vaccine Fluvax on children following reports in Australia of some cases of convulsions

Flu vaccination ban goes national after fever, convulsion risk – WA today – Chris Thomson

West Australian health authorities are trying to determine if the entire Fluvax drug, or just batches, have caused children under five to convulse – and

WA Suspends All Flu Vaccination – TopNews United States – Amit Pathania

The Western Australian Government is revealed to have suspended all flu vaccinations related to children under the age of five, while it carries the

Results 127 of about 27 related articles. Search took 0.04 seconds.

Full coverage

Flu jab scare sparks call for surveillance system

ABC Online‎14 minutes ago‎
Dozens of children have suffered serious adverse reactions after receiving the flu vaccine in WA. (AFP: Jewel Samad) The number of children suffering

Fevers in 60 children linked to flu vaccine

Sydney Morning Herald‎17 minutes ago‎
More than 60 West Australian children may have had adverse reactions to the flu vaccine, the state’s health department says. West Australian Health Minister

Dozens of Australian children fall ill from flu vaccine

Telegraph.co.ukBonnie Malkin‎1 hour ago‎
Doctors across Australia have been ordered to stop giving young children the seasonal flu vaccine after 44 children fell ill hours after being immunised.

Australia Tells Doctors to Stop Flu Shot for Children

BusinessWeekMarion Rae‎1 hour ago‎
April 23 (Bloomberg) — Australia’s government said children aged five years and younger shouldn’t be given CSL Ltd.’s seasonal flu vaccine

Don’t give children flu jab: chief medical officer

Sydney Morning Herald‎1 hour ago‎
Drug regulators are urgently investigating whether the seasonal flu vaccine is safe for children, after the nation’s top doctor said they shouldn’t receive

Ministry warns over flu vaccine

TVNZ‎1 hour ago‎
The Ministry of Health is warning doctors not to give a particular type of flu vaccine to children under 5, after reports of children suffering convulsions

Fluvax flu vaccine warning after child convulsions

Stuff.co.nz‎1 hour ago‎
Doctors have been warned not to use popular flu vaccine Fluvax on preschoolers after reports of children convulsing. The Health Ministry said it had

Children’s flu vaccine suspended

ABC Online‎1 hour ago‎
SHANE MCLEOD: The country’s chief medical officer has suspended the flu vaccine for children under five. The decision comes after 23 children in Perth

Probe on flu shots after kids fall ill

Herald Sun‎3 hours ago‎
UPDATE 1pm: DRUG regulators are urgently investigating whether the seasonal flu vaccine is safe for children, after the nation’s top doctor said they

Health scare halts flu vaccine for kids

The Australian‎5 hours ago‎
DOCTORS have been told to stop giving the seasonal flu vaccine to children under five amid a serious health scare in Western Australia.

Children sick after flu jab

ABC Online‎8 hours ago‎
Dozens of children have suffered serious adverse reactions after receiving the flu vaccine in WA. The Health Department has suspended the free flu

Flu jabs suspended in WA

Sydney Morning Herald‎11 hours ago‎
The West Australian government has temporarily suspended its free flu vaccination program for children under five after some youngsters developed high

Flu shots suspended after kids hospitalised

ABC Online‎20 hours ago‎
The Western Australian Government has suspended all flu vaccinations for children under five while it investigates a spike in admissions to Princess

Doctors: Stop flu vaccine for children

Daily Telegraph‎1 hour ago‎
Australia’s chief medical officer has told doctors to stop giving the seasonal flu vaccine to children. DOCTORS have been told to stop giving NSW children

NZ children suffer serious reactions to flu vaccine

Radio New Zealand‎1 hour ago‎
Some New Zealand children have suffered serious adverse reactions as a result of receiving the seasonal flu vaccine. The Government of Western Australia on

Child flu vaccine reactions mystery

6minutesJared Reed‎2 hours ago‎
A leading WA GP who helped launch the state’s childhood flu campaign says it is not yet known if adverse reactions seen were caused by a “bad

Stop kids’ flu vaccine

Pharmacy News‎4 hours ago‎
Australia’s chief medical officer has told all GPs and immunisation providers to stop giving seasonal flu vaccine to children under five years due to a

Flu vaccine ban for children under 5 after kids fall ill in Perth

Courier MailRod Chester‎7 hours ago‎
Australia’s chief medical officer has told doctors to stop giving the seasonal flu vaccine to children. AUSTRALIAN health authorities have announced a

Child flu shots suspended in West Australia

Radio New Zealand‎7 hours ago‎
Western Australia has suspended free flu vaccinations for children under five, after at least one became seriously ill and dozens suffered serious adverse

WA kids in flu vaccine alert

The West Australian (blog)‎12 hours ago‎
The State Government has suspended its free flu vaccine program for WA children aged under five after 22 children became ill and were taken to Princess

Here comes the flu bug

North Shore Times‎17 hours ago‎
FLU leads to 2500 deaths and 18000 hospitalisations a year in Australia, according to the Australian Influenza Specialist Group. It is generally not the flu

Flu vaccine arrivals delayed

Rockhampton Morning Bulletin‎Apr 21, 2010‎
IT is believed the Icelandic volcano eruption has caused further delays to the arrival of seasonal influenza vaccinations in Central Queensland.

No flu shots for kids in WA

Ninemsn‎16 hours ago‎
The Western Australian government has put a halt on all flu shots for young children, after reports of many suffering adverse side effects.

Flu vaccine linked to convulsions

Otago Daily Times‎40 minutes ago‎
Doctors in New Zealand have been advised against using the influenza vaccine Fluvax on children following reports in Australia of some cases of convulsions

Flu vaccination ban goes national after fever, convulsion risk

WA todayChris Thomson‎6 hours ago‎
West Australian health authorities are trying to determine if the entire Fluvax drug, or just batches, have caused children under five to convulse – and

WA Suspends All Flu Vaccination

TopNews United StatesAmit Pathania‎12 hours ago‎
The Western Australian Government is revealed to have suspended all flu vaccinations related to children under the age of five, while it carries the

Govt suspends flu injections after major health scare

The West Australian (blog)‎20 hours ago‎
The State Government has urgently suspended its flu vaccine program for children aged under five, after a large number of children presented to Princess

4 Girls Die – India Suspends Cervical Cancer Vaccine

India has suspended the HPV cervical cancer vaccine programme after 4 girls died in India amid allegations of exploitation of participants and violation of ethical guidelines during the earlier “clinical trials” of the vaccine according to a front page story in India’s newspaper, The Hindu and widely reported in other media: Centre halts HPV vaccine project Aarti Dhar Thursday 8th April 2010.

The HPV vaccine has been associated with serious adverse effects with high levels of reported adverse reactions.  Death and debilitating illness have been claimed but officials do not acknowledge an association: Gardasil Victims – In Memoriam – Healthy Young Women – Aged 15 to 21.

CHS has previously reported that UK health officials have wrongly assumed the human papilloma virus (HPV) vaccine can prevent 70 per cent of cases of cervical cancer and media have reported that “German experts said the assumptions simply did not stand up to scrutiny, and that women remained at risk“: Experts Cast Doubt on Claim for ‘Wonder’ Cancer Jabs Sunday Express 31 May 2009: Cervical cancer jabs cast into doubt after experts question effectiveness Scotland On Sunday 10th May 2009.

The drive for mass vaccination programmes internationally is the result of the drug industry’s changing business plans from the failing blockbuster patented drug model to hugely lucrative mass multiple vaccinations for the world’s 6.5 billion people.  But those who raise valid public and child health  safety concerns are routinely ‘label libelled’ as ‘anti-vaccine’, ridiculed and in the case of some medical professionals, hounded out of their jobs.

Germany’s Robert Koch Institute, which makes recommendations on the public funding of vaccines, had to review the nation’s programme in May 2009 after 13 experts called for a reassessment of its HPV vaccination programme and an end to “misleading information” about the effectiveness of the jab.  A spokeswoman said: “Because of the public discussion and some new reports and new statements from the 13 professors, the committee will publish a statement within the next few weeks.”

Dawn Primarolo MP for Bristol South since 1987

Dawn Primarolo MP for Bristol South since 1987

The UK’s New Labour Government has been aggressively pursuing the HPV vaccine programme in schools out of sight of parental control: HPV Vaccine Questioned Internationally CHS 31 May 2009.

Some consent forms reportedly had no decline option.   There have been anecdotal reports of young girls being cross-examined in school corridors by health officials on parental consent issues. British Health Minister Dawn Primarolo is closely associated with the pursuit of the policy.

The Sunday Express reports Professor Martina Doren, of the Charitie Hospital in Berlin:

What concerns us is that the two manufacturers of the vaccine aren’t always using facts. They claim that a lot of high-risk strains of cancer-causing virus are protected against but equally there are others that are not. If protection is not more than 20 per cent then that is an awful lot of money to be spending, particularly as the vaccines have quite serious side-effects.”

EXCLUSIVE: EXPERTS CAST DOUBT ON CLAIM FOR ‘WONDER’ CANCER JABS – By Lucy Johnston and Martyn Halle – Sunday May 31,2009

A spokesman for GlaxoSmithKline, which makes Cervarix, was unable at the time to provide figures on cases of pre-cancerous cells in women who have taken the vaccine, compared with those who have not.

Scottish Conservative health spokeswoman Mary Scanlon said at the time: “Given this new research, it is now incumbent on the Scottish Government and the chief medical officer to review the vaccination programme to ensure that it lives up to the expectations of preventing cervical cancer.”

The HPV vaccine programme is based on recommendations of the UK’s Joint Committee on Vaccination and Immunisation. This highlights questions over the competence of the UK’s JCVI to make recommendations on UK vaccination programmes and the competence of medical professionals in general to express opinions on scientific matters.

The JCVI has a documented history of recklessness over vaccination policy and a needle-happy reputation along with concerns about financial and other conflicts of interest: Secret British MMR Vaccine Files Forced Open By Legal Action but from April 1 last year has been given unfettered control of UK Government vaccination policy for England: UK Government Hands Drug Industry Control of Childhood Vaccination.  And as the British Medical Journal confirms: Doctors are not scientists — Smith 328 (7454): BMJ.

If the vaccine is not effective, then its adverse effects cannot be justified but in the UK we see no official comment on the vaccine’s risk profile.  This highlights how public safety issues fail to be addressed as a result of  what some claim is a quasi-religious belief created by the drug industry in the importance of vaccines and the fear medical professionals have of making public criticisms on safety grounds.

Alongside the expansion of vaccination programmes the childhood prevalence of lifetime conditions like asthma, allergies, autism, diabetes and others requiring further medications have increased substantially.

The Bill Gates’ Microsoft type business model is one of the emerging replacement business models for the drug industry.  Almost everyone has Windows software on their PC – almost everyone will be vax’ed.  Gates quickly became a multi-billionaire.  With vastly more people to vaccinate than computers requiring software the lure of money for the pharmaceutical industry is substantial.

______________________________________________________________

MORE NEWS STORIES 1/6/09 –

Rush to introduce vaccination throws up worrying questions – The Scotsman – 01 June 2009 By Marisa de Andrade

Fears over reactions to cervical cancer jab – The Scotsman – 01 June 2009 – By Marisa de Andrade

Call to review cancer vaccine after Germany demands more medical proof – The Scotsman – 2nd June 2009

______________________________________________________________

For detailed information and references on the German issues, see:-

Scientists in Germany call for a reassessment of the HPV vaccination and an end to misleading information

Germany’s Robert Koch Institute is Questioning the effectiveness of the HPV vaccines

Holy Hormones, Honey! — The Greatest Story Never Told

Documents on HPV Vaccines Gardasil and Cervarix

May 24th, 2009


Cynthia Janak
Research Journalist
Founder & President
International Coalition of Advocates for the People

Leslie Botha
Researcher and Broadcast Journalist
Vice-President
International Coalition of Advocates for the People

Treatise on Gardasil from the United States

This paper will focus on five areas: (1) Compromised immune systems in adolescents and potential vaccine reaction; (2) Exposure of HPV to infants and children prior to inoculation; raising concern that the vaccine will be rendered ineffective (Botha); (3) Examination of FDA documents regarding adverse events and efficacy. Neurological affects of Aluminum (Janak); (4) The fast tracking of Gardasil through the FDA without due scientific process and adequate research (Janak); (5) The pharmaceutical industry in the United States has systematically influenced the regulatory agencies and research facilities to fast track drug trials and manipulated their outcome. (Chevalier-Batik) Link to document.

United States Concern for Europe with regards to Cervarix HPV vaccine.

This paper will focus on four areas: (1) European Public Assessment Report, (26/11/2008 Cervarix-H-C-721-II-04), (2) Cervarix© Product Information (PI_Cervarix.pdf.), (3) MHRA (Medicines and Healthcare products Regulatory Agency) March, 2009 and May, 2009.  (4) Media reports. (brackets my emphasis) Link to document.

United Kingdom Concerns Regarding HPV-GM Vaccines

The following points are the serious concerns of the above authors from the United Kingdom (representing Scotland and England) who have researched the Cervarix vaccine in depth. They have noted media concern over many young girls adversely affected by serious illnesses, such as several forms of paralysis including Bells palsy, hemiparesis, hypoaesthesis and Guillaine-Barre Syndrome.   Convulsions, seizures and epileptic fits, along with diminished vision have also been cited. The UK Health Minister, Dawn Primaralo and Scottish Health Minister Shona Robison, deny that these illnesses are connected to the vaccine and that they are coincidental in nature.

The Dutch Cervarix Concerns

We probably speak a different language than you do. Not only because we’re Dutch, but also because we’re not scientists, medical specialists or journalists. We consider ourselves professors in everyday life and even more, we’re mothers. It was September 2008 when we first read an article about Gardasil. Meanwhile it has become a daily routine to read all the    news (good and bad) about HPV, Gardasil and Cervarix. Although we had read enough about what was going on in the US we never expected to come in the middle of the same scenario in Holland. Link to document.

One Mother’s Plea

Karen Maynor of New Mexico lost her daughter, Megan Hild to the Gardasil vaccine on November 15, 2008.  Megan was a healthy, vital 20-year-old young woman with great aspirations –and no history of previous medical problems. Megan had just finished the second in the series of the Gardasil vaccination in September of 2008.

Cervarix Safety Analysis – Dated: March 5th, 2009

Cervarix Safety Analysis – Dated: May 21st, 2009

UK General Medical Council Told Docs “Commit Fraud for MMR Vaccine Bonuses”

The UK’s General Medical Council issued formal written advice to UK medical doctors to commit fraud on the UK’s National Health Service for personal financial gain: Target Payments for Preventive Health Measures” which asked and answered the question “Can GPs remove some children from their lists, temporarily, for the purpose of calculating the MMR target payment?” [full quotes below].

If UK doctors met target levels for vaccinations they qualified for bonus payments.  One way of claiming was to make a false return.  The GMC’s advice was for doctors to file false returns of the numbers of patients who had received the MMR vaccine.  Doctors were advised to take unvaccinated child patients off the patient list temporarily to claim the bonuses but also to ensure the parent agreed, [thereby implicating parents in the fraud].

The GMC is the UK statutory body established to protect, promote and maintain the health and safety of the public by ensuring proper standards in the practice of medicine by medical doctors.  Dishonesty, financial impropriety and fraud fall within its purview [in more ways than one it would seem].

This is the same organisation which recently found Professors Walker-Smith, Simon Murch and Dr Andrew Wakefield guilty of numerous charges filed by Sunday Times’ journalist Brian Deer.  No parent complained and the doctors enjoy wide support amongst parents of many autistic children they did their best to help.  Other doctors who have refused to toe the UK’s Department of Health line on medical practice have found themselves facing or threatened with proceedings by the GMC including amongst many others these four cases: UK’s GMC, Dr Jayne Donegan’s Story, Vaccines & MMR – – Dr Sarah Myhill – – Dr Peter Mansfield – –  Dr. Barry Durrant-Peatfield.

So if it concerns getting MMR vaccine uptake up to help the drug industry, fraud is fine.  But make sure you implicate the parents and what better way to do that than to pressure them into agreeing their children become temporary patients possibly for emergency treatment only or else be dumped from the patient roster completely. But if you raise valid concerns about the safety of vaccinations watch out.

What should the GMC have said?  The GMC should have given a clear lead to doctors and should have said [but did not] that temporary removals of child patients from a GP’s roster is never an option because it is neither ethical nor honest  and that such bonus payments created a conflict of interest between the doctor’s financial gain and the welfare of the child patient.

The GMC is independent (allegedly) of the NHS and of Government but in practice is run and controlled by the UK medical heirarchy and paid for by the medical profession.  Where the GMC finds that a doctor is not fit to practise, it has legal power to erase that doctor’s name from the medical register, to suspend the doctor from the register or to place conditions on the doctor’s practice. These restrictions apply to practice in any sector of employment in any part of the UK.

The GMC has a great notoriety in the UK with frequent calls for it to be abolished, suggested legislative threats: “Minister to look again at NHS bill’s threat to GMC” British Medical Journal: 1999 February 20; 318(7182): 482 and has attracted critical analysis of its decisions including in peer reviewed journal papers:

The Intimidation of British Pediatricians” Carole Jenny Pediatrics, Apr 2007; 119: 797 – 799.

United Kingdom General Medical Council Fails Child Protection” Catherine Williams Pediatrics, Apr 2007; 119: 800 – 802;

Meadow, Southall, and the General Medical Council of the United Kingdom” David L. Chadwick, Henry F. Krous, and Desmond K. Runyan Pediatrics, Jun 2006; 117: 2247 – 2251;

It is a criminal offence in England to aid abet, counsel or procure the commission of a criminal offence – such as obtaining pecuniary advantage by deception.

The GMC Formal Advice to Doctors to Commit Fraud

The GMC posed the question “Can GPs remove some children from their lists, temporarily, for the purpose of calculating the MMR target payment?” in an article entitled “Target Payments for Preventive Health Measures” first published in GMC News in June 2003.

And the GMC’s answer was effectively “it’s OK provided you have patient consent“.  It seems it also happens to be OK if it helps to increase the MMR uptake figures.  The advice was not offered for other vaccinations.

The GMC also failed to make mention of the financial and moral impropriety of doing so in their answer to the question they themselves posed:-

This must not be done without the parents’ agreement. Parents must be given a full explanation of what was proposed and why, their child’s rights as an NHS patient, and the implications for their child’s future care. Doctors working within the NHS must treat all patients entitled to NHS services on an equal footing. So temporarily removing a child from a GPs list must not adversely affect their care, for example in accessing secondary care and out-of-hours services, or in providing relevant information to ensure continuity of care and allow effective working with other agencies. Doctors must act honestly in their financial dealings. So GPs must ensure that any arrangement to remove a child from their list and re-register them for ‘immediately necessary treatment’, or on some other basis, would be in line with their contractual obligations to the NHS.

So provided the doctor does what the GMC advises and ensures “that any arrangement … would be in line with their contractual obligations to the NHS” it is fine as “Doctors must act honestly in their financial dealings“.

All this is of course barking mad.

The GMC also advised that if the evidence is available this is not contrary to GMC guidance on good medical practice:-

Are temporary removals from a GPs list acceptable to the GMC? In the absence of evidence that ‘temporary removals’ satisfy the concerns outlined at Q5, we cannot give any reassurance that such arrangements would be seen as consistent with our guidance on good practice.

The conflict with the GMC’s other advice is clear.  The GMC advised UK doctors “must not ask for or accept any inducement, gift or hospitality which may affect or be seen to affect the way you prescribe for, treat or refer patients.“: Conflicts of interest – guidance for doctors

But it seems the GMC do not mind when it comes to MMR, even where the inducement is so strong it encourages fraud on the NHS.  But then, the GMC did not seem to mind about that either.

Ironically  “GMC Today” newsletter carried a story titled “Is the NHS immune to fraud?” [Oct 2005] about reducing and reporting fraud in the National Health Service, stating:-

Most people who work in and use the NHS are honest, but there is a minority that tries to defraud it of its valuable resources. By working to reduce fraud and corruption to an absolute minimum and hold it there permanently, the NHS CFSMS can release these resources for better patient care. In the largest organisation in Europe, even a small proportion of fraudulent staff and patients has a huge impact. Fraud is committed by a range of NHS professionals, who might claim for work not undertaken, alter prescriptions, create ghost patients or make fraudulent claims for out of hours visits, advice not given or treatment not provided. In some areas, claims by NHS professionals fell by between 43% and 54% after processes were fraud-proofed.

It is now accepted that even the NHS is not immune to fraud.

The GMC has an agreement on cooperating and coordinating with the NHS Counter Fraud service.  The story gave a number to call the confidential NHS Fraud and Corruption Reporting Line and an email address too.  It reports:-

If you have a concern about a fraud taking place within the NHS, please call the confidential NHS Fraud and Corruption Reporting Line on 0800 028 40 60. All calls will be dealt with by trained staff and professionally investigated. Lines are open Monday to Friday 8 am–6 pm. You can also email us at nhsfraud@cfsms.nhs.uk at any time.Memorandum of Understanding between the General Medical Council (GMC) and the National Health Service Counter Fraud Service (NHS CFS)

We had not got the heart to tell ’em.  Would you?

When Was This?

When this news was published by The OneClickGroup in October 2007 the GMC’s response was to claim the advice was withdrawn in 2006.  But the fact the advice was published at all is damning.  Not only that, the advice continued to be published on the GMC website as late as 7th October 2007 with no indication to doctors it had been withdrawn.

After The OneClickGroup’s exposée the GMC removed the page containing the advice from its website and republished the advice but with a banner across it claiming “Withdrawn November 2006”: Target Payments for Preventive Health Measures.

Additionally, the advice was published for over 4 years from June 2003 until October 2007 [just about the time the GMC was ready to attack Wakefield, Walker-Smith and Murch].

Who Ran The GMC Then?

The President when the advice was first published until 2009 was Sir Graeme Catto – also incumbent when the GMC started the proceedings against Walker-Smith, Murch and Wakefield.

So it just goes to show, you cannot trust anyone in “authority” these days.

Anyone wanting to make a complaint to the GMC?  Here is where you do it:-

Making a complaint

But don’t hold your breath waiting.

Sir Graeme’s email address and contact details at The University of Aberdeen are found here:-

http://vcs.abdn.ac.uk/medicine_therapeutics/staff/SirGraemeCatto.shtml

[But probably not for much longer!]

 

UK “Faked” National Autism Data To Declare MMR Vaccine “Safe”

UK children are nearly 5 times more likely to have autistic conditions than adults according to the results of the first ever UK government survey to assess the numbers of adults with the condition: [“Autism Spectrum Disorders in adults living in households throughout England – Report from the Adult Psychiatric Morbidity Survey 2007The NHS Information Centre.]

But the British public were told instead that the survey shows rates in adults and children have always been the same so that that vaccines like MMR cannot be to blame for the increasing rates in children. The UK National Health Service funded the survey and made these claims.

Survey Authors Couldn’t Find Enough Adult Autistics

There were early rumours in 2008 the authors could not find numbers of adult autistic spectrum condition [ASC] cases matching numbers in children.

The survey failed to find a single case of an adult with “typical” or “classic” autism, found in approximately 30%  of  ASC children. “Typical” or “classic” autism is a type of ASC controversially claimed in 1998 might be associated with the MMR vaccine.

The authors also failed to find sufficient adult ASC cases overall – just 19 in 7,451 adults, being “higher functioning” ASCs – mainly Asperger’s Syndrome. This represents an overall rate of just under 1 in 300 potential adult cases and not the officially claimed 1 in 100 for children.

The authors say that if they had carried out the survey differently they might have found four times as many adults a further 46 or 47 ASC cases to come up with the same figure as for children.   Using already estimated data they claimed to be able estimate-on-the-estimate that the adult autism rate for the entire UK is the same as in children [1 in 100].

The survey’s original design meant it was highly unlikely any cases would be “missed” and instead that cases would be over-estimated.   This calls into question the authors’ claims to be able to estimate such a large number of “missed” cases.   The survey design was broadly based.  An unlikely 72% of the adult  participants were selected as potentially having one of four mental illnesses [rather than just ASC]. The study was also designed so that those most likely to have an ASC were interviewed and those unlikely to were excluded.

Whilst designed to estimate the maximum number, the survey as published was also based solely on data for Asperger’s Syndrome from the Adult Psychiatric Morbidity Survey 2007 and not other ASCs.  That is not what the NHS has been telling the media and public. The study authors stated in their prior May 2008 news release that there were to be two surveys in their study, the second to cover other ASCs: University of Leicester to lead audit of adults with autism Eurekalert 9-May-2008. But neither the media nor the public were told by the NHS that the second survey had not been carried out and that no data from it was included in the final survey report.

It is not credible that for none of the other psychiatric conditions in the Adult Psychiatric Morbidity Survey 2007 it seems was it considered necessary to “estimate” “missed” cases – and particularly not an unusually high 3 out of four cases.  The data used is the identical data collected from the identical subjects by the same people at the same time as part of and using the identical study design.

And therefore also the prevalence of ASCs in adults cannot be 1% in any event and also cannot be the same as in children [also contrary to the public claims made by the NHS].

On the basis of the results so far the NHS would have had to claim the prevalence of ASCs in adults is substantially greater than in children and it would have to explain how that could be.

Details of how the missed Aspergers cases were estimated were not provided.  None appear in the survey report to show how the authors calculated this to arrive at an estimated overall adult ASC prevalence figure of 1 in 100.

The NHS also needs to explain of how it came to issue a news release claiming this survey was of the prevalence of adults with ASCs when it is not.  This appears to show that the NHS funded a survey report, assured the Statistics Authority of its validity as “national statistics” when even the title of the report is not accurate and then used it in the media and in public to bolster a policy position when not justified in doing so.

The explanation given of the calculation of “missed cases” appears to be that of all potential cases of adults with ASCs identified by telephone interview only 630 were selected for interview.  The researchers then estimated what they thought they would have found if they interviewed all “potential cases” and multiplied up the 19 cases found to arrive at 73.

Difficulties with this include the remarkably high numbers of adults identified as “potential” ASC cases – more than one in every two adults – or half [ie. 2,854 adults out of a possible 5,329 eligible for consideration].  This demonstrates the inaccuracy of the probabilities the researchers assigned to potential ASC cases and in particular the bias to substantially over estimating the potential numbers of ASC cases.

This is compounded by only 19 cases being found in those deemed most likely to have an ASC and selected for interview.

The estimate of 1 in 100 is also based on what appear  the very same and remarkably inaccurate “probabilities” for selection devised by the researchers.

This does not appear scientific.  It is also compounded by the same researchers claiming wrongfully that their results are for all adults with ASCs when the documented facts  show the data was collected for potential Asperger Syndrome cases only. [Added 16/Feb/2010]

Autism In Children Already Higher Than 1 in 100

A further problem with the survey is that two recent formal peer reviewed journal published studies have found the rate in children is  not 1 in 100 but much higher.  A 2006 study [Baird] found a rate in children of 1 in 85 and a recently published study by Baron-Cohen et al of 2005 data found a  rate of ASC’s in children of 1 in 64 when children not yet diagnosed were taken into account.  This gives a rate of ASC in children 5 times higher than the 1 in 300 indicated by the survey’s results.  Neither of these studies are mentioned in the survey although members of the same team were involved in the Baron-Cohen study, and Professor Baron-Cohen was a consultant to the survey.

Impossible for Adult ASC Rate to Be Same as Childrens’

The authors inexplicably also fail to explain how their estimate of ASC rates in adults is the same as in children when their results show ASC rates in adults and children are significantly different:-

  • Aspergers Syndrome rates in adults on these results are 40% higher than in children;
  • correspondingly Aspergers Syndrome cases in children compared to adults would have to have substantially decreased for this to be so;
  • the rate of “classic” autism has leapt from zero in adults to 30% of ASC cases in children;
  • adults with “classic” autism do not exist.

Identical Figures – A Remarkable Coincidence

The addition of the authors’ hypothetical “estimated” cases provides exactly the same rate of 1 in 100 previously accepted for children.  This is despite the authors themselves warning the results should be approached with caution because of the inaccuracies.  In such circumstances if rates were the same then a similar figure might be expected but not exactly the same one.

The 1% figure for children was stated in pre publicity announcing the start of survey: University of Leicester to lead audit of adults with autism Eurekalert 9-May-2008. “Author bias” in favour of finding a pre-determined figure favourable to the study funder is a well-known phenomenon in formal medical literature.

Breaching the codes of practice prohibiting the release of national statistics for government policy purposes the UK National Health Service’s publicity put out to the media on publication of the survey focussed on claiming ASC rates in adults and children were identical and that therefore the MMR vaccine did not cause ASCs.  This was not the stated purpose of the survey and the authors make no mention of the vaccine-autism issue.  Media stories included: Autism rates back MMR jab safety Michelle Roberts BBC Tuesday, 22 September 2009 and Autism just as common in adults, so MMR is in the clear Sarah Boseley The Guardian Tuesday 22 September 2009.

Survey Does Not Live Up To Its Title

The survey was originally announced to establish the UK adult autism rate for the first time by finding what were then being claimed to be “missed” adult cases of autism.

The publicity claimed “The new prevalence study now underway will give the first ever accurate picture of how many adults have the condition.” [Emphasis added]University of Leicester to lead audit of adults with autism Eurekalert 9-May-2008. The purpose was to inform UK authorities in planning service provision for adults autistics.

The authors used “second-hand” data collected in 2007 which covered only potential adult cases of Asperger’s Syndrome unsuitable for the claimed purpose. The authors planned an additional part of the survey to collect data on adults with other ASCs such as “typical” or “classic” autism but failed to mention this or any resulting data or results in their recently published survey report.  They stated in 2008:-

The prevalence study will make use of new data collected in 2007 by NatCen and Professor Brugha’s team to record the number of adults with Asperger’s syndrome and high functioning autism. There will also be an additional part to the study on the number of people with autism who have more complex needs and learning disabilities. The aim of the combined research will provide good epidemiological information in terms of prevalence and the characteristics and problems of this group.”

University of Leicester to lead audit of adults with autism Eurekalert 9-May-2008.

Many Anomalies

The standard approach under what is called “DSM IV” to diagnose ASC’s was applied but the authors based their assessments on a broader test for ASCs used in a manner neither accepted or relied by other professionals nor scientifically validated. Inexplicably the survey’s results of the DSM IV diagnoses were neither used nor published.

The 1 in 100 figure for children is based on formal diagnoses using accepted methods and published in formal peer reviewed medical literature.  The authors’ survey has not been independently reviewed nor has it been assessed for compliance with accepted statistical standards.

The 19 potential adult ASC cases in 7,451 participants included 17 male and 2 female, a rate of 1 in 8.5 whereas 1 in 5 cases in children are girls.

Other problems with the survey include:-

  • Inclusion in the study was based on the ability of selected members of the public to answer questions on the telephone followed by cooperation with a complex psychiatric assessment. The participants were therefore self-selecting and appear unrepresentative of the general population
  • The 19 cases claimed included no one from an ethnic minority, and a very low rate in females (the ratio of females with ASD is known to be 1 in 5 cases in children, but the survey results indicate it is half that in adults at 1 in 10)
  • Cooperation of more than half the 14,000 households approached is a remarkable and unexplained achievement. The questionnaire screened for psychotic disorder, Asperger syndrome, borderline personality disorder, and anti-social personality disorder.  Were the participants told this and would they have participated had they known?
  • The survey authors give a 95% “confidence interval” to their claim their estimate of adult ASC rate is the same as in children.  A confidence interval is a measure of trust in the reliability of the results but despite being the broadly based the survey failed to find the “missing” cases.

  • The survey results were published despite not having been through peer review nor verified for conformance to accepted standards for government statistics

  • Adults with “typical” autism [associated with the MMR vaccine] remain missing despite being a category claimed in the prior publicity to be part of the survey.

Dr Carol Stott commented on the methodology in Age of Autism:-

Whatever claims are made to the contrary this report tells us very little about the number of adults with ASDs – in England or anywhere else. The main problems with the study are with (a) case-definition, (b) ascertainment (c) diagnostic instruments (d) case identification and (e) statistical power.

There is no clearly stated case-definition anywhere in the report. The cases reported are defined loosely in terms of an initial score on a shortened unstandardised non-peer reviewed version of ascreening tool together with a semi-structured clinical interview – the Autism Diagnostic Observation Schedule (ADOS) – that was not designed to act as a stand-alone diagnostic instrument.

The sample selected is not representative of the ASD population. All participants were verbally fluent, living in ordinary households, and able to complete a self-report questionnaire.

The choice of measurement tools is inadequately justified and badly referenced. No details are provided, nor are any sources referenced, on the psychometric properties of the initial screening instrument (AQ-20). The standardized scoring criteria for the ADOS were not followed (using a total cut-off of 10 for Communication + Social Reciprocity, rather than three cut-offs (respectively) of 3, 6 and 10 for Communication, Social Reciprocity and the two combined). Additionally the authors over state the validity of the ADOS as a tool for use in adult populations. Module Four (used in the study) was standardized on a sample of only 70 adults aged between 16 and 44. Ages in the study sample range from 16 – 75.

The technical appendix, which is intended to provide information about the derivation of the AQ-20 is statistically naïve, unclear and potentially inaccurate. It is not clear for example, what is meant by the phrase on pg 16 of Appendix C “….once the final set of predictors had been selected, a regression equation was available for predicting the prevalence of ADOS.” Neither is it clear whether General Linear Modelling, Linear Regression or both were used to derive final items.

Finally, inferences are made about the lack of a significant association between age-groups and ASD prevalence without reference to statistical power. In a study of this size, with only 19 identified (unweighted) cases, the likelihood is that the study was underpowered to detect such differences.A valid and reliable study of the population frequency of a disorder requires clear and robust case definition, validated instruments, standardized procedures and adequate statistical power. An initial evaluation of this report suggests it fails on all counts.