Autism – Why Autism Research Goes Nowhere – The Researchers Who Take Us Down All The Blind Alleys

Have you ever wondered why supposedly no one knows where “all the autism” is coming from?  Here we set out a blatant example of a misdirection of research results taking the medical professions and the public down a blind alley. 

In the case of the paper “Advancing Paternal Age and Autism” Arch Gen Psychiatry. 2006;63:1026-1032 the authors had and published data which was and remains fundamental to proving the increase in autistic conditions since the expansion in the vaccine programmes in the mid to late 1980s is real and substantial.

For the best part of two decades health officials around the world have insisted untruthfully that the increases in autistic conditions since the 1980s are attributable to “better diagnosis” and “greater awareness”.  They also used to insist that autistic conditions are caused by genetics [have "internal" causes] until it started to be established that the huge increases could not be accounted for on such a basis – because if it was all genetic then the numbers should have been the same all along over centuries.

What the data from “Advancing Paternal Age and Autism” showed and shows was that prior to the introduction of vaccines to Israel the figure for cases of childhood [ie typical or Kanner] autism was 8.4 in 10,0000 children and there were even fewer cases of Asperger’s syndrome so the increase in cases of Aspergers is even more dramatic and serious than even that of childhood autism cases.

The data the authors obtained when compared to current data shows that not only has the incidence and prevalence of childhood autism increased dramatically but also that the incidence and prevalence of Asperger’s syndrome has been even more dramatic since the mid 1980s and dwarfs the increase in autism.  The data was obtained using current diagnostic criteria so was and is comparable to current data for current cases. So what the data and results of this paper really show is that the allegation the increase in autistic conditions is “better diagnosis” and “greater awareness” is false. You can read more about this here:

Autism Figures – Existing Studies Show Shocking Real Increase Since 1988

The authors not only ignored what seems a very obvious finding from their data and results but also misdirected the medical profession and the public away from that finding and down an obscure and blind alley.

Medicine in general is the best example of misdirection of research efforts where commercial and conflicting interests – ie pure greed for making money – seem to ensure that research in many areas is directed down all the blindest of blind alleys and the obvious avenues are either ignored or the research is suppressed or prevented.  The research funds are spent on research guaranteed not to find causes or cures, but at the very best only for drug treatments to be paid for over a lifetime of non cure treatments with drug adverse effects of the drugs aplenty. 

There is a great deal of money to be made that way over many decades.  “Genetic” research is a great general example where billions of US tax dollars have been spent and there is little to show for it – and especially where autistic conditions are concerned. 

Good old medieval serfdom and feudalism never died they have just been refined and redefined.  The majority, the 21st century “serfs”, pay their feudal “tithe” to their new feudal Lords in different ways.  In the 21st Century this means paying with their health and sometimes their lives – not much change there then.

Instead of focussing on an important result the authors of Advancing Paternal Age and Autism made a very different and obscure claim.   The claim was that fathers aged over 40 had a higher probability of having autistic children.  The authors made that the focus of their paper.  The claim was made on the basis of scant data.  The paper was a statistical study [ie this was tobacco science not clinical investigations] and this claim was based on a very small sample with a poor confidence interval.  Fathers aged over 40 involved in the sample accounted for 3 per cent of the children concerned and the confidence in the figures was very wide and thus of extremely low reliability.

Misdirection from studies like this one must obviously be holding back the uncovering of fundamental information regarding autistic conditions and supports and enables government health officials to continue to make over far too many years the kinds of false claims they have been making about the causes of autistic conditions.

The authors and the institutions for which they work need to explain themselves.  Israeli parents who performed their military service deserve better than this – which looks like it is mostly by Americans exploiting their connections with Israel.

Here are the details of the institutions and of the authors:

  • Department of Psychiatry, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1230, New York, NY 10029 (Drs Reichenberg, Silverman, and Davidson),
  • Seaver Center for Autism Research (Dr Silverman), Mount Sinai School of Medicine;
  • Department of Epidemiology, Mailman School of Public Health, Columbia University (Drs Gross, Bresnahan, Harlap, Malaspina, and Susser);
  • New York State Psychiatric Institute (Drs Gross, Bresnahan, Malaspina, and Susser), New York;
  • Institute of Psychiatry, King’s College, London, England (Dr Reichenberg);
  • Department of Psychiatry, Chaim Sheba Medical Center, Tel Hashomer (Drs Weiser and Davidson);
  • School of Social Work, Bar Ilan University, Ramat-Gan (Dr Rabinowitz);
  • School of Social Work, Hebrew University, Jerusalem (Dr Shulman);
  • Medical Corps, Israel Defense Forces, Tel Aviv (Drs Lubin and Knobler), Israel.

Whooping Cough Vaccine – Doesn’t Work – GSK Says “We Never Bothered to Check”

STOP PRESS 21/5/12:

See update: Major Whooping Cough Epidemics – Vaccine Not Working

ORIGINAL ARTICLE CONTINUES BELOW

___________________________

According to a recently published paper not only does whooping cough vaccine “wear off” within as little as three years of administration [assuming it ever "wore on" in the first place] but [according to Reuters] the original manufacturer GlaxoSmithKline never bothered to check whether it worked.  And 81 percent of recent whooping cough cases in California were in children fully vaccinated and teenagers and adults are now put at risk when they would have had lifelong immunity contracting the disease naturally:

Witt MA, Katz PH, Witt MJ, Unexpectedly Limited Durability of Immunity Following Acellular Pertussis Vaccination in Pre-Adolescents in a North American Outbreak.

Whooping cough vaccine fades in pre-teens: study – By Kerry Grens Thompson/Reuters NEW YORK | Tue Apr 3, 2012 2:13pm EDT

The Reuters report states:

A spokesperson for GSK, one of the pertussis vaccine makers, …  GSK has never studied the duration of the vaccine’s protection after the shot given to four- to six-year-olds, the spokesperson said.  ……

“We have a real belief that the durability (of the vaccine) is not what was imagined,” said Dr. David Witt, an infectious disease specialist at Kaiser Permanente Medical Center in San Rafael, California, and senior author of the study.  …….

In early 2010, a spike in cases appeared at Kaiser Permanente in San Rafael, and it was soon determined to be an outbreak of whooping cough — the largest seen in California in more than 50 years.  …..

Witt ….. What was very surprising was the majority of cases were in fully vaccinated children. ….. Of the 132 patients under age 18, 81 percent were up to date on recommended whooping cough shots …. “

Isn’t that fraud?  And if so by whom?  Isn’t it at the very least unethical and illegal to promote and sell a medical product, especially for children, making health claims that it will protect them from disease and [of course the much touted] death which are false and no one bothered to check in the first place?  Who in the US where this study was done is responsible for suing GlaxoSmithKline and/or the US Centers for Disease Control over this?

In the rare event that a child dies from something like whooping cough the people to blame are clearly identifiable.  They are doctors and drug companies and government health officials.  Instead of the US National Institutes of Health spending its US$30 billion annual budget on treatments for those rare cases, they pretend vaccines are OK.  Well it is now time parents who want to avoid their children being harmed by vaccines fought back and put the blame squarely where it deserves to rest.

In the 21st Century there is no effective treatment for measles – difficult to believe.  We must demand that effective treatments be developed for these basic childhood diseases and within the next three years.  US presidential hopeful Senator “Newt” Gingrich wants to spend billions of dollars on a moonbase and ridiculous excursions into space.  Well “Newt”, why not spend money on something useful and save all those third world children who die from measles and other basic childhood diseases because they have malnutrition.  No?  Ah, so presidentially, might you always be “hopeful” but never President?  Odd that.

The study authors wrote:

This first detailed analysis of a recent North American pertussis outbreak found widespread disease among fully vaccinated older children. Starting approximately three years after prior vaccine dose, attack rates markedly increased, suggesting inadequate protection or durability from the acellular vaccine.  Witt MA, Katz PH, Witt MJ, Unexpectedly Limited Durability of Immunity Following Acellular Pertussis Vaccination in Pre-Adolescents in a North American Outbreak.

But what do they conclude – that with our sophisticated 21st Century medical “science” we should protect you and your children by developing effective treatments for the minority of cases where symptoms might be problematic rather than pursue the approach of vaccination?  No chance.  Here are the conclusions – yep – give em more vaccines more often – so we will all end up getting loads of vaccines every few years even as adults – good news for the drug companies – but then the authors are all employed by Kaiser Permante [so what else can you expect]:-

Conclusions Our data suggests that the current schedule of acellular pertussis vaccine doses is insufficient to prevent outbreaks of pertussis. We noted a markedly increased rate of disease from age 8 through 12, proportionate to the interval since the last scheduled vaccine. Stable rates of testing ruled out selection bias. The possibility of earlier or more numerous booster doses of acellular pertussis vaccine either as part of routine immunization or for outbreak control should be entertained.

Now if GSK was a supplier of herbal medicines and alternative medicine remedies, it might be panned across the internet by the so-called “skeptics” or even subject to legal action.  Is this a new thing for GSK?  No.  Not at all:  

Glaxo chief: Our drugs do not work on most patients The Independent [UK] By Steve Connor , Science Editor, Monday 08 December 2003

But what of the US CDC?  It is officially a “waste of space” and money. According to the US Senate the CDC “cannot demonstrate it is controlling disease“.  “CDC Off Center” is an extraordinary 115 page review published in June 2007 by the US Senate on the US Centers for Disease Control:-

A review of how an agency tasked with fighting and preventing disease has spent hundreds of millions of tax dollars for failed prevention efforts, international junkets, and lavish facilities, but cannot demonstrate it is controlling disease.” 

CDC OFF CENTER“- The United States Senate Subcommittee on Federal Financial Management, Government Information and International Security, Minority Office, Under the Direction of Senator Tom Coburn, Ranking Minority Member, June 2007.

And if you want to know some really interesting “stuff” about whooping cough [pertussis] and its vaccines you should go over to Inside Vaccines and read up:

An InsideVaccines blog entry about pertussis

Click here to read all about what the pertussis vaccine does (or doesn’t, as the case may be) do in terms of herd immunity.

What does pertussis “look like” in unvaccinated infants and children?

Manufacturer’s Inserts and efficacy statements:

Daptacel- Efficacy of the DTap ranged from 59-89%.

The Tetanus portion of the vaccine has never been tested for efficacy.

Interestingly, the CDC’s Reported Cases and Deaths from Vaccine Preventable Diseases,United States, 1950-2005 shows Pertussis cases at the highest reported rates since 1959. (Vaccine became available in the 1940s).

In the Journal of Theoretical Biology they discuss the failure rate of the pertussis vaccine in New Zealand.

The obtained figures indicate that in New Zealand the effective vaccination rate against pertussis is lower than 50%, and perhaps even as low as 33% of the population. These figures contradict the medical statistics which claim that more than 80% of the newborns in New Zealand are vaccinated against pertussis (Turner et al., 2000). This contradiction is due to the mentioned unreliability of the available vaccine. The fact that the fraction of immune population obtained here is considerably lower than the fraction of vaccinated population implies a high level of vaccination failure.

The Official Journal of the American Academy of Pediatrics addresses the issue of investigator bias affecting efficacy trials.

In the course of a large pertussis vaccine efficacy trial we realized that investigator compliance could have a major impact on calculated vaccine efficacy.

Conclusions. Our data suggest that observer compliance (observer bias), can significantly inflate calculated vaccine efficacy. It is likely that all recently completed efficacy trials have been effected by this type of observer bias and all vaccines have considerably less efficacy against mild disease than published data suggest.

A study completed on vaccinated children in Israel concluded that the pertussis vaccine does not prevent transmission, it merely prevents the subjects from getting or feeling ill and makes them a source of infection – ie no herd immunity – the disease propagation is not prevented by vaccination – it just makes the carriers of the disease invisible (ie. the vaccine makes the pertussis infection subclinical) and therefore just as much a threat to those children who cannot be vaccinated as if they had the disease naturally [thereby defeating the big argument put up by health officials about parents' duty to protect other children by having their children vaccinated]:-

We tested 46 fully vaccinated children in two day-care centers in Israel who were exposed to a fatal case of pertussis infection. Only two of five children who tested positive for Bordetella pertussis met the World Health Organization’s case definition for pertussis. Vaccinated children may be asymptomatic reservoirs for infection.   ………….

Vaccinated adolescents and adults may serve as reservoirs for silent infection and become potential transmitters to unprotected infants (3-11). The whole-cell vaccine for pertussis is protective only against clinical disease, not against infection (15-17). Therefore, even young, recently vaccinated children may serve as reservoirs and potential transmitters of infection:

Srugo I, Benilevi D, Madeb R, et al Pertussis infection in fully vaccinated children in day-care centers, Israel.  Emerg Infect Dis. 2000 Sep-Oct;6(5):526-9. [Department of Clinical Microbiology, Bnai Zion Medical Center, Haifa, Israel]

Granted, we are using the acellular pertussis now in the US, but it’s widely acknowledged that the whole-cell was in fact more efficacious (but more reactive). So, even this vaccine which “worked better” than what we are currently using, didn’t prevent transmission/infection. It prevented the symptoms.

Interesting discussion of how the pertussis toxin prevents/delays appropriate antibody response, thus allowing infection of immune hosts: Kirimanjeswara GS, Agosto LM, Kennett MJ, Bjornstad ON, Harvill ET: Pertussis toxin inhibits neutrophil recruitment to delay antibody-mediated clearance of Bordetella pertussis Research article, The Journal of Clinical Investigation 2005: 115:12, 3494 December 2005 [Department of Veterinary and Biomedical Sciences and Department of Entomology, The Pennsylvania State University, University Park, Pennsylvania, USA.]

New Paper – Polio Vaccine – Disease Caused by Vaccine Twice As Fatal – Third World Duped – Scarce Money Wasted – Polio Eradication Impossible

According to a new paper published today in the April issue of Indian Journal of Medical Ethics, polio vaccine appears to cause a clinically identical disease which is twice as deadly as polio and the WHO polio eradication programme should be halted: ‘Polio programme – let us declare victory and move on [click title for full .pdf download] by Neetu Vashisht and  Jacob Puliyel of the Department of Pediatrics at St Stephens Hospital in Delhi [for online web version click here and for PubMed abstract click here].

The paper records a failure to investigate NPAFP [non polio acute flacid paralysis] which is clinically indistinguishable from polio paralysis but twice as deadly.  Data from India’s National Polio Surveillance Project shows the NPAFP rate increased in proportion to the number of polio vaccine doses administered.  Independent studies show that children  identified with NPAFP “were at more than twice the risk of dying than those with wild polio infection”.

India was polio-free in 2011, but that year there were 47500 cases of NPAFP.  NPAFP has increased in incidence  in areas where many doses of polio vaccine were used.  

The authors report that, nationally, the NPAFP rate is now twelve times higher than expected.  In the states of Uttar Pradesh  and Bihar — which have pulse polio rounds nearly every month–the NPAFP rate is 25 and 35 fold higher than the international norms.

 ….. while India has been polio-free for a year, there has been a huge increase in non-polio acute flaccid paralysis (NPAFP).  In 2011, there were an extra 47500 new cases of NPAFP. Clinically indistinguishable from polio paralysis but twice as deadly, the incidence of NPAFP was directly proportional to doses of oral polio received. Though this data was collected within the polio surveillance system, it was not investigated. The principle of primum-non-nocere was violated.”

[ED:  Does this paper appear to confirm that the claimed eradication of polio has been achieved by redefining cases of paralytic polio as something else in order to remove from the statistics cases of paralytic polio caused by polio vaccines?  See Inside Vaccines: Polio and Acute Flaccid Paralysis which suggests that the "polio" eradication campaign by WHO appears to have always been a "fools errand" and the unsuspecting world  (third and all else) has been duped.]

Additionally, WHO’s polio eradication campaign will never end because it will never eradicate polio:

The long promised monetary benefits from ceasing to vaccinate against poliovirus will never be achieved,

India was taken off the list of polio-endemic countries by the World Health Organisation (WHO) two months ago but will now have to continue spending scarce health funds on the programme forever.  They argue that the huge costs of repeated rounds of OPV and the parallel rise alongside the use of the vaccine of the more deadly non-polio acute flaccid paralysis (NPAFP) shows that monthly administration of OPV must cease.  

Our resources are perhaps better spent on controlling poliomyelitis to a locally acceptable level  rather than trying to eradicate the disease.”

The authors point out that while the anti-polio campaign in India was mostly self-financed it started with a token donation of two million dollars from abroad.

The Indian government finally had to fund this hugely expensive programme, which cost the country 100 times more than the value of the initial grant.”

The doctors note that it was long known to the scientific community that eradication of polio was impossible because scientists had synthesized poliovirus in a test-tube as early as in 2002.  “The sequence of its genome is known and modern biotechnology allows it to be resurrected at any time in the lab,” they report.  “Man can thus never let down his guard against poliovirus.

According to the authors it was unethical for WHO and Bill Gates to promote this programme when they knew 10 years ago that it was never to succeed.

Getting poor countries to expend their scarce resources on an impossible dream over the last 10 years was unethical.  This is a startling reminder of how initial funding and grants from abroad distort local priorities, ”the authors note.  “From India’s perspective the exercise has been an extremely costly both in terms of human suffering and in monetary terms. It is tempting to speculate what could have been achieved if the $ 2.5 billion spent on attempting to eradicate polio, were spent on water and sanitation and routine immunization.

In conclusion they say that:

the polio eradication programme epitomizes nearly everything that is wrong with donor funded ‘disease specific’ vertical projects at the cost of investments in community-oriented primary health care (horizontal programs).

The WHO’s current policy calls for stopping oral polio vaccine (OPV) vaccination  three  years after the last case of poliovirus-caused poliomyelitis.  Injectable polio vaccine (IPV), which is expensive, will replace OPV in countries which can afford it.

The risks inherent in this strategy are immense, ”Puliyel and Vashisht warn. “Herd immunity against poliomyelitis will rapidly decline as new children are born and not vaccinated. Thus, any outbreak of poliomyelitis will be disastrous, whether it is caused by residual samples of virus stored in laboratories, by vaccine-derived polioviruses or by poliovirus that is chemically synthesized with malignant intent.

[ED: This article includes quotes from the authors' news release.]

Shocking New US Official Autism Figures – Kids With Autistic Conditions At Record High 1 in 88, 1 in 54 Boys

The new figures in the US Centers for Disease Control report, released on March 29 and published in last week’s Morbidity and Mortality Weekly Report (MMWR), states that more than 1 percent, or 1 in every 88 US children, is diagnosed with autism today, including 1 in 54 boys. This is a 78 percent increase in 6 years (2002-2008) and a 10-fold (1000 percent) increase in reported prevalence over the last 40 years. The report uses the same methodology that produced the CDC’s 2009 prevalence findings of 1 in 110 children with autism.

And despite a US$11.5 Bn annual budget the CDC still has no answers except that it has nothing to do with the vast number of vaccines they are responsible for pumping into US children every year

But if you want confirmation from US government officials that vaccines can cause autistic conditions you just have to read the quotes from them here made on US broadcast TV news back in 2008 when they were caught flatfooted with the breaking of the Hannah Poling story [Hannah got a secret settlement of US$20 for her autistic condition caused by 9 vaccines in one day - as conceded by Uncle Sam's health officials and medical expert advisors]:

Vaccination Causes Autism – Say US Government & Merck’s Director of Vaccines

Chile First Developing Country to Stop Use of Mercury in Vaccines

Decision Comes as WHO Meets to Discuss Global Treaty on Mercury Use

WASHINGTON, April 3, 2012 /PRNewswire-USNewswire/ — Chile has become the first developing country to stop the use of mercury in vaccines.

In meetings with the Coalition for Mercury-Free Drugs (CoMeD) held last week in Santiago, Chile, the current Vice President of the Chilean Senate, Alejandro Navarro Brain, committed to adopting legislation in the Senate that would prohibit the mercury-based preservative Thimerosal from vaccines.

Thimerosal, which is 49% mercury by weight, continues to be used as a preservative in vaccines and other drugs worldwide, despite the fact that it is a human neurotoxin and that safer, less toxic alternatives are readily available.

Chile’s decision comes as the World Health Organization (WHO) meets today in Geneva, Switzerland, to discuss a global, legally binding treaty on mercury use. That meeting will examine alternative vaccine preservatives, as well as the economic, programmatic, and manufacturing implications of moving to single-dose, preservative-free vaccines.

While applauding the WHO for giving the issue of mercury use in vaccines the urgent attention it merits, CoMeD expressed serious reservations about WHO’s decision to meet in closed-door session.

Noting that past closed-door sessions have led to “repeated and, we believe, untrue declarations that there is no evidence of harm from the use of Thimerosal in vaccines,” the Reverend Lisa K. Sykes, President of CoMeD, states, “Such unfounded assertions have led to the establishment of two standards of vaccine safety, one which is predominately mercury-free for developed, western countries and one that is mercury-preserved for developing countries.”

As a result, Rev. Sykes continues, “The most vulnerable among us continue to be intentionally exposed to mercury from Thimerosal in childhood vaccines. This exposure is entirely avoidable, and must be stopped.”
Dr. Mark R. Geier, a CoMeD Director, agrees, adding, “Recent statements by those holding national and global responsibility for vaccine safety are difficult to reconcile with the known and published toxicity of Thimerosal.”

According to CoMeD, numerous scientific studies and extensive peer-reviewed scientific and medical papers have all concluded that Thimerosal poses a significant health risk. Thimerosal manufacturers also acknowledge that the preservative can cause mild to severe mental retardation in children.

For additional information about CoMeD and its work to ban mercury from drugs, including vaccines, worldwide, visit http://www.mercury-freedrugs.org.

World Autism “Awareness” Day 2012 and We Are Not Buying It Any More

Here is a good post on The Thinking Mom’s Revolution posted today April 2, 2012

Did you hear the crashing thud last week when the CDC announced that 1 out of every 88 children has Autism? That was the sound of the medical establishment losing its moral authority in the Autism conversation.   Despite Tom Insel, head of the IACC, spinning the message again as “better diagnosing”, the sharp reality of the rise of the Autism numbers cut through his assurances.

We are at a watershed moment much like a point in the television news coverage of the Vietnam War immediately following the Tet Offensive in January 1968. The horrific images caught on camera and the number of reported casualties was so grim they didn’t match the cheery sound bites fed to the media from the American military leadership.

In the Autism Crisis, you could see the beginning of a palpable shift last week. In the news coverage you glimpsed a bit of skepticism in the eyes of the reporters being fed the same lines, by the parade of frequent denialists, that were the mainstay of the conversation several years ago when the new number was 1 out of 150 children. Perhaps this is because Autistic children aren’t just statistics anymore; they belong to every one of us.  There isn’t anyone left who doesn’t have a connection to an Autistic child. The party line “better diagnostics” doesn’t fit with what every single one of us, including the camera man and reporter, is experiencing on the ground. We see Autistic children everywhere. And the second equally clear reality; we didn’t grow up with Autistic children.

Read on for more:

World Autism “Awareness” Day 2012 and We Are Not Buying It Any More

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